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Patent Agency Ranking
11.发明申请公开(公告)号：US20230027988A1
公开(公告)日：2023-01-26
申请号：US17811738
申请日：2022-07-11
IPC: G06T11/00 , A61B5/0515 , A61B5/00
Abstract: The present disclosure includes: transforming a time-domain voltage signal collected by an MPI system device to a frequency domain; calculating a square root of a square sum of a real part and an imaginary part at each frequency point of a frequency domain signal; arranging acquired amplitudes in a descending order, and acquiring a screening threshold by an amplitude ratio method; screening an amplitude through the screening threshold and constructing frequency domain signal data; acquiring a row vector of a system matrix corresponding to each frequency point of the data, so as to construct an update system matrix; and solving, based on the frequency domain signal array and the update system matrix, an inverse problem in a form of a least square based on an L2 constraint to obtain a three-dimensional magnetic particle concentration distribution result, so as to achieve a fast reconstruction of the MPI system.
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公开(公告)号：US10564103B2
公开(公告)日：2020-02-18
申请号：US15534882
申请日：2014-12-10
Inventor： Jie Tian , Yamin Mao , Chongwei Chi , Xin Yang
IPC: A62B1/04 , G01N21/64 , H04N5/33 , H04N5/247 , H04N5/232 , G01N21/25 , G02B23/24 , G01N21/359 , H04N5/372 , H04N5/225 , G02B23/26
Abstract: A dual-mode optical molecular imaging navigation apparatus with a switchable field of view, and an imaging method thereof, are provided in the embodiments of the disclosure, the apparatus including: a camera module configured to perform a color imaging and a fluorescence imaging; a switching module configured to switch between an open imaging mode and an endoscopic imaging mode as per imaging requirements; an open imaging module configured to perform observation and imaging with a large field of view; an endoscopic imaging module configured to perform observation and imaging with a deep field of view; a data processing module configured to provide a camera control software and image capturing, processing and display method; and a support module configured to support and connect the navigation apparatus.
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公开(公告)号：US11816767B1
公开(公告)日：2023-11-14
申请号：US18218115
申请日：2023-07-05
Inventor： Jie Tian , Zechen Wei , Hui Hui , Xin Yang , Huiling Peng
IPC: G06K9/00 , G06T11/00 , G06T5/00 , G06T5/10 , A61B5/0515
CPC classification number: G06T11/006 , A61B5/0515 , G06T5/002 , G06T5/10 , G06T2207/10072 , G06T2207/20081 , G06T2207/20084
Abstract: A method and system for reconstructing a magnetic particle distribution model based on time-frequency spectrum enhancement are provided. The method includes: scanning, by a magnetic particle imaging (MPI) device, a scan target to acquire a one-dimensional time-domain signal of the scan target; performing short-time Fourier transform to acquire a time-frequency spectrum; acquiring, by a deep neural network (DNN) fused with a self-attention mechanism, a denoised time-frequency spectrum; acquiring a high-quality magnetic particle time-domain signal; and reconstructing a magnetic particle distribution model. The method learns global and local information in the time-frequency spectrum through the DNN fused with the self-attention mechanism, thereby learning a relationship between different harmonics to distinguish between a particle signal and a noise signal. The method combines the global and local information to complete denoising of the time-frequency spectrum, thereby acquiring the high-quality magnetic particle time-domain signal.
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14.发明申请公开(公告)号：US20230094291A1
公开(公告)日：2023-03-30
申请号：US17811235
申请日：2022-07-07
Inventor： Jie Tian , Yanjun Liu , Hui Hui , Lin Yin , Xin Feng
IPC: A61B5/0515 , G01R33/54
Abstract: The present disclosure belongs to a field of biomedical imaging technology, and in particularly to a non-uniform excitation field-based method and system for performing a magnetic nanoparticle imaging. The present disclosure includes: separating the non-uniform excitation field into independent space and current time functions by a spatialtemporal separation method; calculating a normalized signal peak through the current time function; constructing a reconstruction mathematical model based on the normalized signal peak and an imaging subunit volume; and quantitatively reconstructing a spatial distribution of a nanoparticle by combining the normalized signal peak, a non-uniform spatial function of the excitation field and the reconstruction mathematical model, so as to achieve the magnetic nanoparticle imaging of a to-be-reconstructed object.
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公开(公告)号：US10524665B2
公开(公告)日：2020-01-07
申请号：US15520928
申请日：2014-10-22
Inventor： Jie Tian , Chongwei Chi , Xin Yang
Abstract: A handheld molecular imaging navigation system comprises a multi-spectral light source module configured to provide light in a plurality of different spectrum bands in a time division control manner according to a control signal sequence to irradiate an inspected object; a time division control module configured to generate the control signal sequence; an optical signal acquisition module configured to acquire a near-infrared fluorescence image and a visible light image of the inspected object in a time division control manner according to the control signal sequence provided by the time division control module; and a processing module configured to perform image processing on the acquired near-infrared fluorescence image and visible light image according to the control signal sequence to fuse the visible light image and the fluorescence image and output the fused image, and output a feedback signal according to the acquired near-infrared fluorescence image and visible light image.
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