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公开(公告)号：US20200224242A1
公开(公告)日：2020-07-16
申请号：US16775034
申请日：2020-01-28
Applicant: InnovaPrep LLC
Inventor： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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公开(公告)号：US09738918B2
公开(公告)日：2017-08-22
申请号：US14313618
申请日：2014-06-24
Applicant: InnovaPrep LLC
Inventor： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
CPC classification number: C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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公开(公告)号：US20140308659A1
公开(公告)日：2014-10-16
申请号：US14313618
申请日：2014-06-24
Applicant: InnovaPrep LLC
Inventor： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
CPC classification number: C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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