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公开(公告)号：US20220125333A1
公开(公告)日：2022-04-28
申请号：US17511487
申请日：2021-10-26
Applicant: INNOVAPREP LLC
Inventor： David S. Alburty , Andew E. Page , John D. Birkenholz , Kathleen Ruegsegger , Ann K. Packingham , Zachary A. Packingham , Alec D. Adolphson , Pamela S. Murowchick , Hugh Olsen , Bryan C. Long , Steven D. Graham
Abstract: Devices and methods are described for using normal human breath to separately capture particles from inhaled and exhaled breath for analysis. This device can be constructed as a wearable device worn as a mask with separately removable filters on the inside and the outside of an efficient collection material.
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公开(公告)号：US20230146816A1
公开(公告)日：2023-05-11
申请号：US17984204
申请日：2022-11-09
Applicant: INNOVAPREP LLC
Inventor： Michael Fischer , Bryan Long , Steven D. Graham , Sidney J. Spry , Alec Adolphson , John D. Birkenholz , Andrew E. Page , David S. Alburty
IPC: B01L3/00
CPC classification number: B01L3/505
Abstract: Devices, systems, and methods are disclosed which relate to using a use large area surface sampler with invertible bag for collection of biological and non-biological particles prior to subsequent analysis. The large area surface sampler with invertible bag uses an inverted bag with bonded sampling material to first serve as a sampling device followed by the bag being turned right side out and the captured particles being extracted inside of the bag. The device includes measures for sealing liquid in the sampling material using a protective cup at time of manufacture. This enables users to simply remove the protective cup and perform wet surface sampling prior to turning the bag right side out and removing captured particles from the sampling material with repeated compressions. The described device, systems and methods allow users to capture and elute surface samples for human clinical, veterinary, food safety, pharmaceutical, outbreak investigations, forensics, biodefense and bioterrorism response, environmental monitoring, and other applications where collection of samples from surfaces and humans or animals is required.
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公开(公告)号：US20160302776A1
公开(公告)日：2016-10-20
申请号：US15132046
申请日：2016-04-18
Applicant: InnovaPrep LLC
Inventor： Alec D. Adolphson , Ann K. Packingham , Andrew E. Page , David S. Alburty , Zachary A. Packingham , John D. Birkenholz , Michael F. Fischer
CPC classification number: A61B10/02 , A61B10/0096 , A61B2010/0216
Abstract: Devices, systems and methods are disclosed which relate to using wet foam elution for removal of particles from swabs and wipes. This allow users to capture particles from surfaces and recover them by elution into small sample volumes for subsequent detection for human clinical, veterinary, food safety, pharmaceutical, outbreak investigations, forensics, biodefense and bioterrorism response, environmental monitoring, and other applications where collection of samples from surfaces and humans or animals is required. More specifically, the swabs or wipes are used to collect samples in the standard ways that commercially available swabs and wipes are in use today; from, for instance, food preparation surfaces in food plants, from production equipment in pharmaceutical facilities, for collection of dry powders during bioterrorism event response, and for collection of clinical samples such as nasal, throat, nasopharyngeal, and wounds.
Abstract translation: 公开了涉及使用湿泡沫洗脱来从拭子和擦拭物去除颗粒的装置，系统和方法。 这允许用户从表面捕获颗粒，并通过洗脱到小样本体积中进行回收，以便随后检测人类临床，兽医，食品安全，制药，疫情调查，取证，生物识别和生物恐怖反应，环境监测和其他应用，其中收集 需要表面和人体或动物的样品。 更具体地，拭子或擦拭物用于以目前市售的拭子和擦拭巾的标准方式收集样品; 例如食品工厂中的食物制备表面，制药设备中的生产设备，用于在生物恐怖事件应答期间收集干粉，以及用于收集诸如鼻，喉，鼻咽和伤口的临床样品。
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公开(公告)号：US20250025834A1
公开(公告)日：2025-01-23
申请号：US18778834
申请日：2024-07-19
Applicant: INNOVAPREP LLC
Inventor： Andrew E. Page , David Goad , David S. Alburty
IPC: B01D61/14
Abstract: Highly efficient and rapid filtration-based methods for isolation and concentration of exosomes and extracellular vesicles from biological fluids, including urine, which utilize pretreatment, prefiltration, wash steps and isolation and concentration using the concentrating pipette are disclosed.
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公开(公告)号：US20210077080A1
公开(公告)日：2021-03-18
申请号：US17103912
申请日：2020-11-24
Applicant: InnovaPrep LLC
Inventor： Alec D. Adolphson , Ann K. Packingham , Andrew E. Page , David S. Alburty , Zachary A. Packingham , John D. Birkenholz , Michael F. Fischer
Abstract: Devices, systems and methods are disclosed which relate to using wet foam elution for removal of particles from swabs and wipes. This allow users to capture particles from surfaces and recover them by elution into small sample volumes for subsequent detection for human clinical, veterinary, food safety, pharmaceutical, outbreak investigations, forensics, biodefense and bioterrorism response, environmental monitoring, and other applications where collection of samples from surfaces and humans or animals is required. More specifically, the swabs or wipes are used to collect samples in the standard ways that commercially available swabs and wipes are in use today; from, for instance, food preparation surfaces in food plants, from production equipment in pharmaceutical facilities, for collection of dry powders during bioterrorism event response, and for collection of clinical samples such as nasal, throat, nasopharyngeal, and wounds.
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Patent Agency Ranking
公开(公告)号：US10544445B2
公开(公告)日：2020-01-28
申请号：US15681078
申请日：2017-08-18
Applicant: InnovaPrep LLC
Inventor： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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公开(公告)号：US20170369925A1
公开(公告)日：2017-12-28
申请号：US15681078
申请日：2017-08-18
Applicant: InnovaPrep LLC
Inventor： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
CPC classification number: C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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公开(公告)号：US12060601B2
公开(公告)日：2024-08-13
申请号：US16775034
申请日：2020-01-28
Applicant: InnovaPrep LLC
Inventor： David S. Alburty , Andrew E. Page , Zachary A. Packingham , Daniel B. Marske
CPC classification number: C12Q1/24 , C12Q1/04 , G01N1/4005 , G01N1/4077 , G01N2001/4088
Abstract: A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
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公开(公告)号：US11986168B2
公开(公告)日：2024-05-21
申请号：US17103912
申请日：2020-11-24
Applicant: InnovaPrep LLC
Inventor： Alec D. Adolphson , Ann K. Packingham , Andrew E. Page , David S. Alburty , Zachary A. Packingham , John D. Birkenholz , Michael F. Fischer
CPC classification number: A61B10/02 , A61B10/0096 , A61B2010/0216 , B01L3/5029 , G01N2001/028
Abstract: Devices, systems and methods are disclosed which relate to using wet foam elution for removal of particles from swabs and wipes. This allow users to capture particles from surfaces and recover them by elution into small sample volumes for subsequent detection for human clinical, veterinary, food safety, pharmaceutical, outbreak investigations, forensics, biodefense and bioterrorism response, environmental monitoring, and other applications where collection of samples from surfaces and humans or animals is required. More specifically, the swabs or wipes are used to collect samples in the standard ways that commercially available swabs and wipes are in use today; from, for instance, food preparation surfaces in food plants, from production equipment in pharmaceutical facilities, for collection of dry powders during bioterrorism event response, and for collection of clinical samples such as nasal, throat, nasopharyngeal, and wounds.
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公开(公告)号：US20210308664A1
公开(公告)日：2021-10-07
申请号：US17222951
申请日：2021-04-05
Applicant: INNOVAPREP LLC
Inventor： John D. Birkenholz , Andrew Edward Page , Zachary A. Packingham , David S. Alburty , Alec D. Adolphson , Steven Dale Graham , Michael F. Fischer
Abstract: Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect and identify. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.
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