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公开(公告)号:US08513239B2
公开(公告)日:2013-08-20
申请号:US12248095
申请日:2008-10-09
申请人: David Joseph Bartkovitz , Jianping Cai , Xin-Jie Chu , Hongju Li , Allen John Lovey , Binh Thanh Vu , Chunlin Zhao
发明人: David Joseph Bartkovitz , Jianping Cai , Xin-Jie Chu , Hongju Li , Allen John Lovey , Binh Thanh Vu , Chunlin Zhao
IPC分类号: A61K31/55 , A61K31/03 , A61K31/44 , A61K31/535 , A61K31/505 , C07D243/06 , C07D243/14 , C07D279/10 , C07D413/08 , C07D403/08 , C07D239/02 , C07D215/02
CPC分类号: C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14 , C07D471/10
摘要: There are provided compounds of the formula or the pharmaceutically acceptable salts thereof, wherein X, Y, Z, V1, V2, R1, R2, R3, R4 and R5 are herein described. These compounds are useful as anticancer agents.
摘要翻译: 提供下式的化合物或其药学上可接受的盐,其中本文描述了X,Y,Z,V1,V2,R 1,R 2,R 3,R 4和R 5。 这些化合物可用作抗癌药。
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公开(公告)号:US20110225735A1
公开(公告)日:2011-09-22
申请号:US12725963
申请日:2010-03-17
申请人: Steve Heroux , Jianping Cai
发明人: Steve Heroux , Jianping Cai
IPC分类号: A47G9/10
摘要: A pillow that can be manipulated into a variety of bent/folded/twisted configurations and can retain each of those configurations until manipulated into a different configuration. The pillow has a segmented toroidal shape and includes an envelope and a flowable fill filling the envelope so that the fill is under positive pressure throughout. The pillow has a plurality of constrictions that, in conjunction with the pressurized fill, provides the pillow with soft hinges that facilitate bending/folding/twisting of the pillow.
摘要翻译: 枕头可以被操纵成各种弯曲/折叠/扭转配置,并且可以保持这些配置中的每一个,直到被操纵成不同的配置。 枕头具有分段的环形形状,并且包括封套和填充信封的可流动填充物,使得填充物处于正压下。 枕头具有多个收缩,其与加压填充物一起为枕头提供有利于枕头弯曲/折叠/扭转的柔性铰链。
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公开(公告)号:US20090076275A1
公开(公告)日:2009-03-19
申请号:US12207674
申请日:2008-09-10
申请人: David Robert Bolin , Jianping Cai , Adrian Wai-Hing Cheung , Robert Alan Goodnow, JR. , Matthew Michael Hamilton , Shiming Li , Lee Apostle McDermott , Weiya Yun
发明人: David Robert Bolin , Jianping Cai , Adrian Wai-Hing Cheung , Robert Alan Goodnow, JR. , Matthew Michael Hamilton , Shiming Li , Lee Apostle McDermott , Weiya Yun
IPC分类号: C07D413/12 , C07D417/12 , C07D471/04
CPC分类号: C07D413/12 , C07D401/14 , C07D403/12 , C07D407/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04
摘要: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
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公开(公告)号:US07504513B2
公开(公告)日:2009-03-17
申请号:US11703306
申请日:2007-02-07
申请人: John Frederick Boylan , Jianping Cai , Nader Fotouhi , Paul Gillespie , Robert Alan Goodnow, Jr. , Kang Le , Christophe Michoud
发明人: John Frederick Boylan , Jianping Cai , Nader Fotouhi , Paul Gillespie , Robert Alan Goodnow, Jr. , Kang Le , Christophe Michoud
IPC分类号: A61K31/427 , C07D417/04 , C07D417/14
CPC分类号: C07D417/04
摘要: The invention is directed to compounds of formula (1) and pharmaceutically acceptable salts thereof, methods for the preparation thereof, and methods of use thereof.
摘要翻译: 本发明涉及式(1)的化合物及其药学上可接受的盐,其制备方法及其使用方法。
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公开(公告)号:US20070203210A1
公开(公告)日:2007-08-30
申请号:US11703306
申请日:2007-02-07
申请人: John Frederick Boylan , Jianping Cai , Nader Fotouhi , Paul Gillespie , Robert Alan Goodnow , Kang Le , Christophe Michoud
发明人: John Frederick Boylan , Jianping Cai , Nader Fotouhi , Paul Gillespie , Robert Alan Goodnow , Kang Le , Christophe Michoud
IPC分类号: A61K31/427 , C07D417/04
CPC分类号: C07D417/04
摘要: The invention is directed to compounds of formula (1) and pharmaceutically acceptable salts thereof, methods for the preparation thereof, and methods of use thereof.
摘要翻译: 本发明涉及式(1)的化合物及其药学上可接受的盐,其制备方法及其使用方法。
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公开(公告)号:USD523984S1
公开(公告)日:2006-06-27
申请号:US29225613
申请日:2005-03-18
申请人: Jianping Cai
设计人: Jianping Cai
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公开(公告)号:US20060069269A1
公开(公告)日:2006-03-30
申请号:US11235375
申请日:2005-09-26
申请人: Kurt Amrein , Jianping Cai , Robert Goodnow , Daniel Hunziker , Bernd Kuhn , Alexander Mayweg , Werner Neidhart
发明人: Kurt Amrein , Jianping Cai , Robert Goodnow , Daniel Hunziker , Bernd Kuhn , Alexander Mayweg , Werner Neidhart
IPC分类号: C07D231/56
CPC分类号: C07D231/56 , C07D401/06 , C07D405/12 , C07D413/12
摘要: Compounds of formula (I) as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R7 have the significances given in the description and claims can be used in the form of pharmaceutical compositions.
摘要翻译: 式(I)化合物
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公开(公告)号:US20050152135A1
公开(公告)日:2005-07-14
申请号:US11034574
申请日:2005-01-13
申请人: Jianping Cai
发明人: Jianping Cai
CPC分类号: F21S6/003 , F21S9/02 , F21Y2115/10 , Y10S362/80
摘要: A portable reading lamp of the invention comprises a base, a head portion and a beanpole to connect the base with the head portion. The head portion is provided with the luminant, which is semiconductor LED. A battery box is provided on the base, the head portion or the beanpole for supplying direct current. The semiconductor LED is used as the luminant in the invention, so the reading lamp of the invention can save energy in high-efficiency (10% electricity consumption of the traditional reading lamp), which also has the following strongpoint: saturated color and ray, infinite motley, switching rapidly, unpolluted, shock-resistant, dampness-resistant, long usage life (100,000 hours), radiation-free and less maintenance. The invention also provides a battery box in the base for supplying direct current, which is very convenient to be used in the field when no external power source can be used.
摘要翻译: 本发明的便携式阅读灯包括底座,头部和豆杆,以将底座与头部连接。 头部设置有作为半导体LED的发光体。 电池盒设置在基座,头部或豆杆上,用于提供直流电流。 在本发明中使用半导体LED作为发光体,因此本发明的阅读灯能够节省高效率(传统阅读灯的10%耗电量)的能量,这也具有以下优点:饱和的颜色和光线, 无污染,无污染,耐冲击,耐潮湿,使用寿命长(100,000小时),无辐射,维护少。 本发明还提供一种用于提供直流电的基座中的电池盒,当不使用外部电源时,这在现场非常方便。
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公开(公告)号:US10335427B2
公开(公告)日:2019-07-02
申请号:US16060412
申请日:2017-05-16
申请人: Jianping Cai
发明人: Jianping Cai , Zhenhe Wang , Jin Li , Yunxuan Li , Ping Jiang , Ju Cui
IPC分类号: A61K31/708 , A61P35/04 , A61P35/00 , A61P35/02
摘要: The present invention discloses a medicament for the prevention and treatment of tumors, in particular relating to the use of 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) in the manufacturing of a medicament for the prevention and treatment of tumors, and a medicament comprising 8-oxo-dGTP for the prevention and treatment of tumors, and falls within the pharmaceutical field. The 8-oxo-dGTP can be used in the manufacturing of a medicament for at least one of the treatment, prevention and control of tumors. The 8-oxo-dGTP has a significant inhibitory effect on tumorigenesis and tumor cell proliferation for many types of tumors, and can serve as a new candidate medicament for the prevention and treatment of tumors. Animal experiments show that the 8-oxo-dGTP is significantly superior to 5-FU in terms of tumor inhibition, therefore has a good industrial availability and great business and social values.
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公开(公告)号:US20090163546A1
公开(公告)日:2009-06-25
申请号:US12325322
申请日:2008-12-01
IPC分类号: A61K31/4709 , C07D231/56 , C07D401/12 , A61K31/454 , A61K31/416 , A61P3/04 , A61P3/10
CPC分类号: C07D231/56 , C07D401/12
摘要: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
摘要翻译: 本文提供式(I)的化合物及其药学上可接受的盐,其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗疾病,例如肥胖症,II型糖尿病和代谢综合征。
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