公开(公告)号：US09217795B2

公开(公告)日：2015-12-22

申请号：US13556331

申请日：2012-07-24

申请人： Peter Hansen ,  Michael E. Casey ,  Stefan B. Siegel

发明人： Peter Hansen ,  Michael E. Casey ,  Stefan B. Siegel

IPC分类号： G01F15/06 ,  G01T1/24

CPC分类号： G01J1/44 ,  G01T1/248 ,  G01T1/2985 ,  H03K3/037 ,  H03K5/135 ,  H03K2005/00078

摘要： Apparatuses and methods are provided that minimize the effects of dark-current pulses. For example, in one embodiment of the invention, a method is provided where a first pixel is struck (i.e., a primary pixel). Pixels struck within a fixed time frame after the primary pixel is struck are referred to as secondary pixels. After a short fixed time frame has expired, the number of primary and secondary pixels is added. If the count exceeds a threshold, the primary pixel was activated by the first (or early) photon from a true gamma event. If the threshold is not met then it is likely the primary pixel generated a dark pulse that should be ignored.

摘要翻译： 提供了使暗电流脉冲的影响最小化的装置和方法。 例如，在本发明的一个实施例中，提供了一种方法，其中第一像素被撞击（即，主像素）。 在主要像素被击打之后的固定时间帧内撞击的像素被称为次要像素。 在短的固定时间段到期后，添加主要和次要像素的数量。 如果计数超过阈值，则主像素由来自真实伽马事件的第一（或早）光子激活。 如果阈值不满足，则主要像素可能产生应忽略的暗脉冲。

公开(公告)号：US08913810B2

公开(公告)日：2014-12-16

申请号：US13555308

申请日：2012-07-23

申请人： Vladimir Y. Panin ,  Michael E. Casey

发明人： Vladimir Y. Panin ,  Michael E. Casey

IPC分类号： G06K9/00 ,  G06T11/00

CPC分类号： G06T11/003 ,  G06T11/006 ,  G06T2211/424

摘要： Methods, and systems therefrom, for generating images from time of flight (TOF) data associated with a scan of at least one object using a positron emission tomography system are provided. The method includes providing initial values for an activity image to yield a current activity image. The method also includes estimating initial values for an attenuation map (μ-map) image based on the TOF data to yield a current μ-map image. The method further includes repeating, until at least one termination condition is met, the steps of updating the current activity image based on at least the current μ-map and a first update algorithm and updating the current μ-map image based on at least on the updated activity image and a second update algorithm. The method also includes outputting an image of the at least one object based on the current μ-map and the current activity image.

摘要翻译： 提供了用于使用正电子发射断层摄影系统从与至少一个物体的扫描有关的飞行时间（TOF）数据生成图像的方法和系统。 该方法包括提供活动图像的初始值以产生当前活动图像。 该方法还包括基于TOF数据估计衰减映射（μ映射）图像的初始值以产生当前的μ映射图像。 该方法还包括重复直到至少一个终止条件被满足为基于至少基于当前μ映射和第一更新算法来更新当前活动图像的步骤，并且至少基于上述步骤更新当前的μ映射图像 更新的活动图像和第二更新算法。 该方法还包括基于当前μ图和当前活动图像输出至少一个对象的图像。

公开(公告)号：US08352811B2

公开(公告)日：2013-01-08

申请号：US12560048

申请日：2009-09-15

申请人： Michael E. Casey ,  Andrew P. Moor ,  Kenneth Puterbaugh

发明人： Michael E. Casey ,  Andrew P. Moor ,  Kenneth Puterbaugh

IPC分类号： G06F11/07 ,  G06F11/25

CPC分类号： G01T1/00

摘要： An event data transmission scheme is provided for reducing positron emission tomography event losses. The event data transmission scheme employs a more effective use of available data bandwidth. Each of a plurality of detector data slots is connected directly to a data aggregation control interface, and the control interface is connected to a coincidence processor.

摘要翻译： 提供一种用于减少正电子发射断层摄影事件损失的事件数据传输方案。 事件数据传输方案更有效地利用可用的数据带宽。 多个检测器数据时隙中的每一个直接连接到数据聚合控制接口，并且控制接口连接到重合处理器。

公开(公告)号：US07851763B2

公开(公告)日：2010-12-14

申请号：US12622623

申请日：2009-11-20

申请人： Bernard Bendriem ,  Michael E. Casey ,  Charles C. Watson

发明人： Bernard Bendriem ,  Michael E. Casey ,  Charles C. Watson

IPC分类号： G01T1/164

CPC分类号： G01T1/2985 ,  G01T7/005

摘要： A method for improving clinical data quality in Positron Emission Tomography (PET). The method provides for the processing of PET data to accurately and efficiently determine a data single-to-noise ratio (SNR) corresponding to each individual clinical patient scan, as a function of a singles rate in a PET scanner. The method relates an injected dose to the singles rate to determine SNR(Dinj),and provides an accurate estimate of a quantity proportional to SNR, similar in function to the SNR(Dinj). Knowledge of SNR(Dinj) permits determination of peak SNR, optimal dose, SNR deficit, dose deficit, and differential dose benefit. The patient dose is fractionated, with a small calibration dose given initially. After a short uptake, the patient is pre-scanned to determine T, S, and R. An optimal does is then determined and the remainder injected.

摘要翻译： 一种改善正电子发射断层扫描（PET）临床数据质量的方法。 该方法提供PET数据的处理，以准确且有效地确定与每个单独的临床患者扫描相对应的数据单一噪声比（SNR），作为PET扫描仪中单打率的函数。 该方法将注射剂量与单次速率相关联以确定SNR（Dinj），并且提供与SNR成比例的量的精确估计，其功能类似于SNR（Dinj）。 SNR（Dinj）的知识允许确定峰值SNR，最佳剂量，SNR赤字，剂量缺陷和差异剂量效益。 对患者剂量进行分级，最初给予较小的校准剂量。 经过短暂摄取后，患者被预先扫描以确定T，S和R.然后确定最佳确定并且剩余部分注射。

公开(公告)号：US20100070808A1

公开(公告)日：2010-03-18

申请号：US12560048

申请日：2009-09-15

申请人： Michael E. Casey ,  Andrew P. Moor ,  Kenneth PUTERBAUGH

发明人： Michael E. Casey ,  Andrew P. Moor ,  Kenneth PUTERBAUGH

IPC分类号： G06F11/00

CPC分类号： G01T1/00

摘要： An event data transmission scheme is provided for reducing positron emission tomography event losses. The event data transmission scheme employs a more effective use of available data bandwidth. Each of a plurality of detector data slots is connected directly to a data aggregation control interface, and the control interface is connected to a coincidence processor.

摘要翻译： 提供一种用于减少正电子发射断层摄影事件损失的事件数据传输方案。 事件数据传输方案更有效地利用可用的数据带宽。 多个检测器数据时隙中的每一个直接连接到数据聚合控制接口，并且控制接口连接到重合处理器。

公开(公告)号：US20090076379A1

公开(公告)日：2009-03-19

申请号：US12125329

申请日：2008-05-22

申请人： James J. Hamill ,  Gunther Platsch ,  Michael E. Casey

发明人： James J. Hamill ,  Gunther Platsch ,  Michael E. Casey

IPC分类号： A61B8/14 ,  A61B5/05

CPC分类号： A61B8/08 ,  A61B5/7285 ,  A61B6/032 ,  A61B6/5247 ,  A61B6/541 ,  A61B8/4245 ,  A61B8/5238 ,  A61B8/543 ,  G01T1/1603

摘要： A medical imaging device has an emission tomograph, at least one ultrasonic (US) probe for providing images giving real-time information about the location of the internal organs of a subject, a tracking system for spatially locating the at least one ultrasonic probe in relation to the medical imaging device, and an image processing unit in which the location information obtained by the ultrasonic probe is used for attenuation correction of image information obtained by the emission tomograph.

摘要翻译： 一种医疗成像装置具有发射断层摄影机，至少一个超声波（US）探头，用于提供给出关于被检体的内部器官的位置的实时信息的图像，用于相对于空间定位至少一个超声波探头的跟踪系统 以及图像处理单元，其中由超声波探头获得的位置信息用于由发射断层摄影机获得的图像信息的衰减校正。

公开(公告)号：US20090072131A1

公开(公告)日：2009-03-19

申请号：US12212457

申请日：2008-09-17

申请人： Mu Chen ,  Vladimir Panin ,  Michael E. Casey

发明人： Mu Chen ,  Vladimir Panin ,  Michael E. Casey

IPC分类号： G01D18/00

CPC分类号： G01T1/2985 ,  A61B6/037 ,  G01T7/005

摘要： The present invention provides a method for estimating crystal efficiency in a PET detector that takes axial compression into account. It does so via an iterative methodology in which a μ-map is first generated and then is used to obtain a solution for the equation L  ( ɛ i ) = ∑ n ∈ N   y n  log  ∑ i , j ∈ span   g ij  ɛ i  ɛ j  x ij - ∑ i , j ∈ span   g ij  ɛ i  ɛ j  x ij , wherein gij is a geometric factor for LOR(i,j), εi and εj are the efficiencies for crystal i and crystal j, and xij is the line integral of the source distribution along LOR(i,j). Once efficiencies are determined, they are used to calibrate the PET detector.

公开(公告)号：US07465927B2

公开(公告)日：2008-12-16

申请号：US11387263

申请日：2006-03-23

申请人： Vladimir Panin ,  Maurizio Conti ,  Michael E. Casey

发明人： Vladimir Panin ,  Maurizio Conti ,  Michael E. Casey

IPC分类号： G01T1/164

CPC分类号： G01T1/1617

摘要： For patient transmission data acquired simultaneously with patient emission data, blank transmission data are acquired in the absence of the patient emission and therefore under count rate conditions different from the count rate conditions of the patient transmission data. To prevent the different count rate conditions from causing artifacts in reconstructed tomographic images, a correction is made for spatially varying count rate effects on the attenuation correction. For example, the blank scan data are adjusted according to the count rate at which the patient emission data are acquired, and the adjusted blank scan data and the patient transmission data are used for attenuation correction of the patient emission data used for reconstructing a tomographic image.

摘要翻译： 对于与患者发射数据同时获得的患者传输数据，在不存在患者发射的情况下获取空白传输数据，因此在与患者传输数据的计数速率条件不同的计数速率条件下获取。 为了防止不同的计数率条件在重建的断层图像中造成伪像，对空间变化的计数率对衰减校正的影响进行了校正。 例如，根据获取患者发射数据的计数率来调整空白扫描数据，并且将经调整的空白扫描数据和患者传输数据用于用于重建断层图像的患者排放数据的衰减校正 。

公开(公告)号：US06565489B2

公开(公告)日：2003-05-20

申请号：US09956378

申请日：2001-09-18

申请人： Sung-Cho Ho ,  Michael E. Casey

发明人： Sung-Cho Ho ,  Michael E. Casey

IPC分类号： A63B21068

CPC分类号： A63B23/0211 ,  A63B21/068 ,  A63B22/0076 ,  A63B22/0089 ,  A63B23/0222 ,  A63B2022/0084 ,  A63B2208/02

摘要： An angle-adjustable rowing exerciser, which includes a wheeled base frame, a fixed mattress and a pivoted mattress supported on the base frame, a transverse frame bar pivotally mounted on the base frame at the bottom, two handlebars respectively adjustably connected to two adjustable ratchet connectors at the ends of the transverse frame bar for turning by hand to rotate the transverse frame bar, and two actuating bars perpendicularly and fixedly connected to the transverse frame bar and forced to tilt the base frame or the movable mattress up and down upon turning of the handlebars.

公开(公告)号：US06413311B2

公开(公告)日：2002-07-02

申请号：US09795174

申请日：2001-02-28

申请人： Charles L. Melcher ,  Ronald Nutt ,  Michael E. Casey

发明人： Charles L. Melcher ,  Ronald Nutt ,  Michael E. Casey

IPC分类号： C30B1520

CPC分类号： C30B15/10 ,  C30B15/00 ,  C30B29/34

摘要： A Cerium-Doped Lutetium Oxyorthosilicate scintillator boule having a graded decay time. The method for manufacturing an LSO:Ce crystal boule having a decay time gradient decreasing from the top end to the bottom end first includes the step selecting an iridium crucible. The crucible is selected based upon its diameter relative to the diameter defined by said crystal boule. The crucible is also selected based upon its volume relative to the volume of the crystal boule to be grown. A Cerium dopant (CeO2) is added to a mixture of Lutetium Oxide (Lu2O3) and Silicon Dioxide (SiO2). The composition is heated until melted to define a melt. A seed crystal is then placed in contact with the melt, is rotated, and slowly withdrawn, thereby yielding an LSO:Ce crystal boule defining a decay time gradient.

摘要翻译： 具有渐变衰减时间的铈掺杂镥氧原硅酸盐闪烁体晶体。 制造具有从顶端到底端衰减的衰减时间梯度的LSO：Ce晶体棒的方法首先包括选择铱坩埚的步骤。 坩埚基于其直径相对于由所述晶体晶粒定义的直径来选择。 坩埚也是根据其相对于待生长的晶体体积的体积来选择的。 将铈掺杂剂（CeO 2）加入到氧化镥（Lu 2 O 3）和二氧化硅（SiO 2）的混合物中。 将组合物加热直到熔化以限定熔体。 然后将晶种与熔体接触，旋转并缓慢抽出，从而产生限定衰减时间梯度的LSO：Ce晶体棒。