-
11.发明授权Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use 有权取代的苯甲酰脲基吡啶基哌啶和吡咯烷羧酸衍生物，其制备方法及其应用公开(公告)号：US07501440B2
公开(公告)日：2009-03-10
申请号：US10795863
申请日：2004-03-08
IPC分类号： A61K31/4545 , C07D401/04
CPC分类号： C07D401/04
摘要： The invention relates to compounds of the formula I where the radicals are as defined, and their physiologically tolerated salts. The compounds are suitable, for example, as medicaments for preventing and treating type 2 diabetes.
摘要翻译： 本发明涉及式Ⅰ化合物，其中基团如所定义，及其生理上耐受的盐。 该化合物例如可用作预防和治疗2型糖尿病的药物。
-
12.发明申请CARBOXYALKOXY-SUBSTITUTED ACYL-CARBOXYPHENYLUREA DERIVATIVES AND THEIR USE AS MEDICAMENTS 有权羧氧基取代的乙酰氧基苯甲醛衍生物及其作为药物的用途公开(公告)号：US20070088083A1
公开(公告)日：2007-04-19
申请号：US11613433
申请日：2006-12-20
申请人： Elisabeth DeFossa , Dieter Kadereit , Thomas Klabunde , Hans-Joerg Burger , Andreas Herling , Karl-Ulrich Wendt , Erich Von Roedern , Karl Schoenafinger , Alfons Enhsen
发明人： Elisabeth DeFossa , Dieter Kadereit , Thomas Klabunde , Hans-Joerg Burger , Andreas Herling , Karl-Ulrich Wendt , Erich Von Roedern , Karl Schoenafinger , Alfons Enhsen
IPC分类号： A61K31/277 , A61K31/24 , A61K31/195 , C07C275/46
CPC分类号： C07C275/54
摘要： The invention relates to acyl-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I, in which the radicals have the stated meanings, and the physiological tolerated salts thereof and processes for preparing them are described. The compounds are suitable for example for the treatment of type II diabetes.
摘要翻译： 本发明涉及酰基羧基苯基脲衍生物及其生理上耐受的盐和生理功能衍生物。 描述了其中基团具有所述含义的式I化合物及其生理耐受盐及其制备方法。 该化合物适用于例如治疗II型糖尿病。
-
13.发明授权Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use 有权羰基氨基取代的酰基苯基脲衍生物，其制备方法及其应用公开(公告)号：US07179941B2
公开(公告)日：2007-02-20
申请号：US10763877
申请日：2004-01-23
申请人： Elisabeth Defossa , Dieter Kadereit , Thomas Klabunde , Hans-Joerg Burger , Andreas Herling , Karl-Ulrich Wendt , Erich Von Roedern , Karl Schoenafinger , Alfons Enhsen
发明人： Elisabeth Defossa , Dieter Kadereit , Thomas Klabunde , Hans-Joerg Burger , Andreas Herling , Karl-Ulrich Wendt , Erich Von Roedern , Karl Schoenafinger , Alfons Enhsen
IPC分类号： C07C273/00 , C07C53/00 , C07C59/00 , C07C229/00 , A61K31/00
CPC分类号： C07D213/82 , C07C275/54 , C07C2601/04 , C07D209/12 , C07D295/033 , C07D307/68 , C07D307/85 , C07D333/38
摘要： The invention relates to compounds of the formula I in which the radicals are defined as specified, and also to their physiologically tolerated salts. The compounds are suitable, for example, as medicaments for preventing and treating type 2 diabetes.
摘要翻译： 本发明涉及式Ⅰ化合物，其中基团按照规定定义，也涉及其生理上耐受的盐。 该化合物例如可用作预防和治疗2型糖尿病的药物。
-
14.发明申请Heterocyclically Substituted Benzoylureas, Process For Their Preparation and Their Use as Pharmaceuticals 审中-公开杂环取代苯甲酰脲，其制备方法及其作为药物的用途公开(公告)号：US20070021474A1
公开(公告)日：2007-01-25
申请号：US11464907
申请日：2006-08-16
申请人： Karl Schoenafinger , Elisabeth DeFossa , Dieter Kadereit , Erich Von Roedern , Thomas Klabunde , Hans-Joerg Burger , Andreas Herling , Karl-Ulrich Wendt
发明人： Karl Schoenafinger , Elisabeth DeFossa , Dieter Kadereit , Erich Von Roedern , Thomas Klabunde , Hans-Joerg Burger , Andreas Herling , Karl-Ulrich Wendt
IPC分类号： A61K31/44 , A61K31/40 , A61K31/277 , A61K31/195 , A61K31/17 , C07C275/40
CPC分类号： C07D211/60 , C07D211/62 , C07D231/12 , C07D231/26 , C07D233/56 , C07D235/18 , C07D249/08 , C07D249/12 , C07D253/07 , C07D257/04 , C07D271/10 , C07D271/113 , C07D307/68
摘要： Heterocyclically substituted benzoylureas, process for their preparation and their use as pharmaceuticals The invention relates to heterocyclically substituted benzoylureas and also to their physiologically tolerated salts and physiologically functional derivatives. Compounds are described of the formula I where the radicals are defined as specified, and also their pharmaceutically acceptable salts and processes for their preparation. The compounds are suitable, for example, for treating type 2 diabetes.
摘要翻译： 杂环取代的苯甲酰脲，其制备方法及其作为药物的用途本发明涉及杂环取代的苯甲酰脲以及其生理上耐受的盐和生理功能衍生物。 化合物描述为其中基团被定义为特定的式I，以及它们的药学上可接受的盐及其制备方法。 该化合物适用于例如治疗2型糖尿病。
-
15.发明授权N-benzoylureidocinnamic acid derivatives, processes for preparing them and their use 有权N-苯甲酰基肉豆蔻酸衍生物，其制备方法及其应用公开(公告)号：US07049341B2
公开(公告)日：2006-05-23
申请号：US10456570
申请日：2003-06-06
申请人： Karl Schoenafinger , Elisabeth Defossa , Dieter Kadereit , Erich Von Roedern , Thomas Klabunde , Hans-Joerg Burger , Andreas Herling , Karl-Ulrich Wendt
发明人： Karl Schoenafinger , Elisabeth Defossa , Dieter Kadereit , Erich Von Roedern , Thomas Klabunde , Hans-Joerg Burger , Andreas Herling , Karl-Ulrich Wendt
IPC分类号： A61K31/24 , A61K31/195 , C07C229/00 , C07C275/00
CPC分类号： C07C275/54
摘要： N-Benzoylureidocinnamic acid derivatives, processes for preparing them and their useThe invention relates to N-benzoylureidocinnamic acid derivatives and to their physiologically tolerated salts and physiologically functional derivatives. The invention thus relates to compounds of formula I, in which the radicals have the given meanings, and to their physiologically tolerated salts and processes for preparing them. The compounds are, for example, suitable for use as antidiabetic agents.
摘要翻译： N-苯甲酰脲基肉桂酸衍生物，其制备方法及其用途本发明涉及N-苯甲酰脲基肉桂酸衍生物及其生理上耐受的盐和生理功能衍生物。 因此，本发明涉及其中基团具有给定含义的式I化合物及其生理上耐受的盐及其制备方法。 化合物例如适合用作抗糖尿病药。
-
16.发明授权Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments 有权杂环取代的7-氨基-4-喹诺酮-3-羧酸衍生物，其制备方法及其作为药物的用途公开(公告)号：US07498341B2
公开(公告)日：2009-03-03
申请号：US11042589
申请日：2005-01-25
申请人： Elisabeth Defossa , Dieter Kadereit , Sven Ruf , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt
发明人： Elisabeth Defossa , Dieter Kadereit , Sven Ruf , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt
IPC分类号： A61K31/4375
CPC分类号： C07D215/56 , C07D401/12 , C07D417/12 , C07D471/04
摘要： The invention relates to heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof.The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.
摘要翻译： 本发明涉及杂环取代的7-氨基-4-喹诺酮-3-羧酸衍生物及其生理上耐受的盐和生理功能衍生物。 本发明涉及其中基团具有所述含义的式I化合物及其生理上耐受的盐。 该化合物适用于例如用于预防和治疗2型糖尿病的药物。
-
17.发明申请7-phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments 有权7-苯基氨基-4-喹诺酮-3-羧酸衍生物，其制备方法及其作为药物的用途公开(公告)号：US20050182085A1
公开(公告)日：2005-08-18
申请号：US11042023
申请日：2005-01-25
申请人： Elisabeth Defossa , Dieter Kadereit , Sven Ruf , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt
发明人： Elisabeth Defossa , Dieter Kadereit , Sven Ruf , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt
IPC分类号： A61K31/4709 , A61K31/4745 , C07D215/36 , C07D471/02
CPC分类号： C07D215/56 , C07D401/06 , C07D471/04
摘要： 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments The invention relates to 7-phenylamino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.
摘要翻译： 7-苯基氨基-4-喹诺酮-3-羧酸衍生物，其制备方法及其作为药物的用途本发明涉及7-苯基氨基-4-喹诺酮-3-羧酸衍生物以及生理上耐受的盐和生理功能衍生物 其中。 本发明涉及其中基团具有所述含义的式I化合物及其生理上耐受的盐。 该化合物适用于例如用于预防和治疗2型糖尿病的药物。
-
18.发明授权Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments 有权环烷基取代的7-氨基-4-喹诺酮-3-羧酸衍生物，其制备方法及其作为药物的用途公开(公告)号：US07470706B2
公开(公告)日：2008-12-30
申请号：US11042770
申请日：2005-01-25
申请人： Elisabeth Defossa , Dieter Kadereit , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt , Sven Ruf
发明人： Elisabeth Defossa , Dieter Kadereit , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt , Sven Ruf
IPC分类号： A61K31/4375
CPC分类号： C07D471/04 , C07D215/36
摘要： The invention relates to cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof.The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.
摘要翻译： 本发明涉及环烷基取代的7-氨基-4-喹诺酮-3-羧酸衍生物及其生理上耐受的盐和生理功能衍生物。 本发明涉及其中基团具有所述含义的式I化合物及其生理上可耐受的盐。 该化合物适用于例如用于预防和治疗2型糖尿病的药物。
-
19.发明授权7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments 有权7-苯基氨基-4-喹诺酮-3-羧酸衍生物，其制备方法及其作为药物的用途公开(公告)号：US07402674B2
公开(公告)日：2008-07-22
申请号：US11042023
申请日：2005-01-25
申请人： Elisabeth Defossa , Dieter Kadereit , Sven Ruf , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt
发明人： Elisabeth Defossa , Dieter Kadereit , Sven Ruf , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt
IPC分类号： C07D471/02 , C07D215/38 , A61K31/44 , A61K31/47
CPC分类号： C07D215/56 , C07D401/06 , C07D471/04
摘要： 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicamentsThe invention relates to 7-phenylamino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof.The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.
摘要翻译： 7-苯基氨基-4-喹诺酮-3-羧酸衍生物，其制备方法及其作为药物的用途本发明涉及7-苯基氨基-4-喹诺酮-3-羧酸衍生物以及生理上耐受的盐和生理功能衍生物 其中。 本发明涉及其中基团具有所述含义的式I化合物及其生理上耐受的盐。 该化合物适用于例如用于预防和治疗2型糖尿病的药物。
-
20.发明申请Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments 有权环烷基取代的7-氨基-4-喹诺酮-3-羧酸衍生物，其制备方法及其作为药物的用途公开(公告)号：US20050182087A1
公开(公告)日：2005-08-18
申请号：US11042770
申请日：2005-01-25
申请人： Elisabeth Defossa , Dieter Kadereit , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt , Sven Ruf
发明人： Elisabeth Defossa , Dieter Kadereit , Thomas Klabunde , Dieter Schmoll , Andreas Herling , Karl-Ulrich Wendt , Sven Ruf
IPC分类号： A61K31/47 , A61K31/4745 , C07D215/36 , C07D471/02
CPC分类号： C07D471/04 , C07D215/36
摘要： Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments The invention relates to cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.
摘要翻译： 环烷基取代的7-氨基-4-喹诺酮-3-羧酸衍生物，其制备方法及其作为药物的用途本发明涉及环烷基取代的7-氨基-4-喹诺酮-3-羧酸衍生物和生理学上 耐受的盐及其生理功能衍生物。 本发明涉及其中基团具有所述含义的式I化合物及其生理上耐受的盐。 该化合物适用于例如用于预防和治疗2型糖尿病的药物。
-
-
-
-
-
-
-
-
-
搜索结果
49 条记录 (耗时 0.025 秒)
