公开(公告)号：US07831296B2

公开(公告)日：2010-11-09

申请号：US10723486

申请日：2003-11-26

申请人： Kenneth F. DeFreitas ,  Baorui Ren ,  Chris Ruth ,  Ian Shaw ,  Andrew P. Smith ,  Jay A. Stein

发明人： Kenneth F. DeFreitas ,  Baorui Ren ,  Chris Ruth ,  Ian Shaw ,  Andrew P. Smith ,  Jay A. Stein

IPC分类号： A61B5/05

CPC分类号： A61B6/502 ,  A61B6/025 ,  A61B6/12 ,  A61B6/464 ,  A61B6/481 ,  A61B6/482

摘要： A method and system for producing tomosynthetic images of a patient's breast. An x-ray source that delivers x-rays through a breast immobilized and compressed between a compression paddle and a breast platform and form an image at a digital x-ray receptor panel. Multiple x-ray images are taken as the x-ray source and the receptor move relative to the immobilized breast. In one preferred embodiment, the x-ray source travels from −15° to +15°. The source can travel in an arc around the breast while the receptor travels linearly while remaining parallel and at the same distance from the breast platform. The sets of x-ray image data taken at different angles are combined to form tomosynthetic images that can be viewed in different formats, alone or as an adjunct to conventional mammograms.

摘要翻译： 一种用于生产患者乳房的合成图像的方法和系统。 x射线源，其通过在压缩桨和乳房平台之间固定和压缩的乳房提供x射线，并在数字X射线受体面板上形成图像。 多个x射线图像作为x射线源，受体相对于固定的乳房移动。 在一个优选实施例中，x射线源从-15°行进到+ 15°。 该源可以沿着乳房周围的弧线行进，同时受体在线性移动的同时保持与乳房平台相同的距离。 组合以不同角度拍摄的X射线图像数据组合以形成可以以不同格式单独或作为常规乳房X线照片附件的辅助视图观察的合成图像。

公开(公告)号：US07792244B2

公开(公告)日：2010-09-07

申请号：US12362275

申请日：2009-01-29

申请人： Kenneth F. DeFreitas ,  Linda Hopponen ,  Ian Shaw ,  Loren Niklason ,  Jay Stein ,  Andrew P. Smith

发明人： Kenneth F. DeFreitas ,  Linda Hopponen ,  Ian Shaw ,  Loren Niklason ,  Jay Stein ,  Andrew P. Smith

IPC分类号： A61B6/04

CPC分类号： A61B6/0414 ,  A61B6/025 ,  A61B6/502

摘要： A breast x-ray imaging method and system that is particularly suited for tomosynthesis imaging but also is useful for conventional mammography. A fluid containing pillow or bag is placed between the breast and a paddle that compresses the breast against a breast platform covering an imaging device, to enhance patient comfort and provide other benefits. Alternatives include a flexible sheet compressing the breast, and a compressible foam, preferably contoured to accommodate a patient's breast.

摘要翻译： 乳房x射线成像方法和系统，其特别适用于断层摄影成像，但也适用于常规乳房X线照相术。 含有枕头或袋的流体放置在乳房和桨之间，该乳房将乳房压靠在覆盖成像装置的乳房平台上，以增强患者的舒适度并提供其它益处。 替代方案包括压缩乳房的柔性片和可压缩的泡沫，优选地轮廓以容纳患者的乳房。

公开(公告)号：US20120150034A1

公开(公告)日：2012-06-14

申请号：US13325495

申请日：2011-12-14

申请人： Kenneth F. DeFreitas ,  Ian Shaw

发明人： Kenneth F. DeFreitas ,  Ian Shaw

IPC分类号： A61B8/00 ,  A61B6/03 ,  G01T1/164 ,  A61B6/04

CPC分类号： A61B8/0825 ,  A61B6/025 ,  A61B6/0414 ,  A61B6/12 ,  A61B6/4417 ,  A61B6/463 ,  A61B6/466 ,  A61B6/469 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B6/566 ,  A61B8/0841 ,  A61B8/0866 ,  A61B8/4245 ,  A61B8/4263 ,  A61B8/4416 ,  A61B8/4438 ,  A61B8/466 ,  A61B8/469 ,  A61B8/483 ,  A61B8/486 ,  A61B8/5261

摘要： A multi-modality cancer screening and diagnosis system is provided that allows cancer screening and diagnosis of a patient using at least two different and sequential three-dimensional imaging techniques without patient repositioning. The system includes a first three-dimensional image acquisition device, a second three-dimensional image acquisition device having a probe with a transmitter mounted thereon, and a positioning paddle for positioning and immobilizing an object to be imaged during the cancer screening and diagnosis procedure. The positioning paddle is designed to facilitate visualization of the breast in both three-dimensional modalities without movement of the patient, and preferably is designed to position the patient with comfort during a diagnosis procedure which uses both imaging modalities.

摘要翻译： 提供了一种多模式癌症筛查和诊断系统，其允许使用至少两种不同且顺序的三维成像技术进行癌症筛查和诊断，而无需患者重新定位。 该系统包括第一三维图像采集装置，具有安装有发射器的探针的第二三维图像采集装置，以及用于在癌症筛选和诊断过程期间定位和固定待成像物体的定位桨。 定位桨被设计成便于立体形式的乳房的可视化而无需患者的移动，并且优选地被设计成在使用成像模态的诊断过程期间使患者舒适地定位患者。

公开(公告)号：US5594769A

公开(公告)日：1997-01-14

申请号：US437793

申请日：1995-05-09

申请人： Anthony J. Pellegrino ,  Kenneth F. DeFreitas

发明人： Anthony J. Pellegrino ,  Kenneth F. DeFreitas

IPC分类号： A61B6/00 ,  A61B10/00 ,  A61B10/02 ,  A61B19/00 ,  A61B6/04

CPC分类号： A61B6/502 ,  A61B6/12 ,  A61B90/11 ,  A61B90/17 ,  A61B10/0233 ,  A61B6/4028

摘要： An add-on biopsy apparatus attached to a conventional mammography apparatus permits stereotactic imaging of a breast held in a mammographic position using an image receiver having a plane positioned perpendicular to the X-ray source. The perpendicularly positioned image plane allows the use of conventional moving scatter reducing grids to improve image contrast and quality of a stereotactic image made with an add-on biopsy apparatus. The biopsy apparatus also includes a control system for position a digital image receiver to compensate for image shifting during stereotactic imaging.

摘要翻译： 附着于常规乳房摄影装置的附加活组织检查装置允许使用具有垂直于X射线源的平面的图像接收器对保持在乳房X光照相位置的乳房进行立体定向成像。 垂直定位的图像平面允许使用常规的移动散射减少网格来改善用附加活检装置制成的立体定向图像的图像对比度和质量。 活检装置还包括用于定位数字图像接收器以在立体定向成像期间补偿图像偏移的控制系统。

公开(公告)号：US5289520A

公开(公告)日：1994-02-22

申请号：US957275

申请日：1992-10-06

申请人： Anthony J. Pellegrino ,  Milton Stoller ,  Kenneth F. DeFreitas ,  David D. Camarra ,  Anthony M. Scandura ,  Richard F. Schutz ,  Jeffrey R. Storm

发明人： Anthony J. Pellegrino ,  Milton Stoller ,  Kenneth F. DeFreitas ,  David D. Camarra ,  Anthony M. Scandura ,  Richard F. Schutz ,  Jeffrey R. Storm

IPC分类号： A61B6/00 ,  A61B6/04 ,  A61B10/00 ,  A61B10/02 ,  A61B19/00

CPC分类号： A61B6/502 ,  A61B6/0435 ,  A61B90/10 ,  A61B90/11 ,  A61B90/17 ,  A61B10/0233 ,  A61B6/4488

摘要： An elongated prone patient-supporting examining table for X-ray mammography is centrally supported at variable heights by a rear pedestal. The table is provided with a central breast-receiving aperture through which the patient's pendulant breast is exposed to a horizontal beam of X-rays from a tubehead source mounted on an arm angularly movable through an arc of some 210.degree. centered on the patient's breast. The patient's feet may be positioned at either end of the elongated table on an extensible footrest, permitting X-ray projection through more than 360.degree. around the patient's body. Diagnosis of suspect lesions and fine needle biopsy are both facilitated by stereotactic examination. Digital imaging using a CCD camera and image enhancement software provides magnification, contrast enhancement, window and level manipulation and high resolution images, with low exposure levels, short exposure times, and greatly reduced imaging times.

摘要翻译： 用于X射线乳房X线照相术的细长易患者支撑检查台由后基座在可变高度处集中支撑。 该台设置有中央乳房接收孔，通过该中心乳房接收孔，患者的侧枝乳房从安装在可以通过以患者乳房为中心的大约210度的弧的角度移动的臂上的管头源暴露于水平的X射线束。 患者的脚可以定位在可伸展脚凳上的细长台的任一端，允许X射线投射穿过患者身体周围超过360度。 通过立体定向检查有助于诊断疑似病变和细针穿刺活检。 使用CCD相机和图像增强软件的数字成像提供放大，对比度增强，窗口和电平操纵以及高分辨率图像，具有低曝光水平，短曝光时间，并大大缩短成像时间。

公开(公告)号：US20130072816A1

公开(公告)日：2013-03-21

申请号：US13611502

申请日：2012-09-12

申请人： John Girgenti ,  Kenneth F. DeFreitas ,  Thomas W. DeYoung

发明人： John Girgenti ,  Kenneth F. DeFreitas ,  Thomas W. DeYoung

IPC分类号： A61B10/02

CPC分类号： A61B90/17 ,  A61B5/062 ,  A61B5/065 ,  A61B10/0041 ,  A61B10/0275 ,  A61B17/3403 ,  A61B90/50 ,  A61B2010/0208 ,  A61B2017/3405 ,  A61B2090/376

摘要： A biopsy device includes a lateral member; a gun mount configured to support a biopsy gun, the gun mount being connected to the lateral member and movable along a first axis with respect to the lateral member, and a sensor which detects a position of the gun mount along the first axis with respect to the lateral member and generates positional data which is provided to an interface module. The gun mount can also be reconfigured in orientations which are offset in a dimension which is orthogonal to the first axis, orientations rotationally offset about the first axis or an axis parallel to the first axis. The lateral member can be in right hand and left hand orientations. Various sensors detect these reconfigurations and provide corresponding data to the interface module for additional calculations and display.

摘要翻译： 活检装置包括侧向构件; 枪支座，其构造成支撑活检枪，所述枪支座连接到所述侧向构件并且可相对于所述侧向构件沿着第一轴线移动;以及传感器，其相对于所述第二轴线相对于所述第二轴线检测所述枪支座的位置 并且产生提供给接口模块的位置数据。 喷枪安装座还可以以与第一轴正交的尺寸偏移的取向重新配置，取向围绕第一轴线或平行于第一轴线的轴线旋转偏移。 侧向构件可以在右手和左手方向。 各种传感器检测这些重新配置，并将相应的数据提供给接口模块以进行额外的计算和显示。

公开(公告)号：US5609152A

公开(公告)日：1997-03-11

申请号：US388810

申请日：1995-02-15

申请人： Anthony J. Pellegrino ,  Milton Stoller ,  Kenneth F. DeFreitas ,  David D. Camarra ,  Anthony M. Scandura ,  Richard F. Schutz ,  Jeffrey R. Storm

发明人： Anthony J. Pellegrino ,  Milton Stoller ,  Kenneth F. DeFreitas ,  David D. Camarra ,  Anthony M. Scandura ,  Richard F. Schutz ,  Jeffrey R. Storm

IPC分类号： A61B6/00 ,  A61B6/04 ,  A61B10/00 ,  A61B10/02 ,  A61B19/00 ,  A61B5/05

CPC分类号： A61B6/502 ,  A61B6/0435 ,  A61B90/10 ,  A61B90/11 ,  A61B90/17 ,  A61B10/0233 ,  A61B6/4488

摘要： A patient-supporting table for performing prone stereotactic mammographic biopsy procedures having a platform with an aperture positioned so as to divide the platform into two supporting portions is disclosed. Each of the supporting portions of the platform are sufficient to support at least a patient's torso and legs. The supporting portions of the platform enable a patient's breast to be pendulantly presented in two different orientations with respect to the aperture which further enables 360.degree. access to a pendulantly presented breast by stereotactic mammography and biopsy apparatus which have rotation ranges substantially less than 360.degree. but more than 180.degree. relative to the aperture.

摘要翻译： 公开了一种用于执行俯卧式立体定向乳房X线摄影活检程序的患者支撑台，具有具有定位成将平台分成两个支撑部分的孔的平台。 平台的每个支撑部分足以支撑至少一个患者的躯干和腿部。 平台的支撑部分使得患者的乳房能够以相对于孔的两个不同取向倾斜地呈现，这进一步使得360°可以通过立体定向乳房X线照相术和活检装置进行垂直乳房X线照相术和活组织检查装置的旋转范围大约小于360度， 相对于孔径大于180度。

公开(公告)号：US08768026B2

公开(公告)日：2014-07-01

申请号：US12150539

申请日：2008-04-28

申请人： Baorui Ren ,  Andrew P. Smith ,  Zhenxue Jing ,  Jay A. Stein ,  Kenneth F. DeFreitas

发明人： Baorui Ren ,  Andrew P. Smith ,  Zhenxue Jing ,  Jay A. Stein ,  Kenneth F. DeFreitas

IPC分类号： A61B6/03 ,  A61B6/00 ,  A61B6/04 ,  A61B5/107

CPC分类号： A61B6/502 ,  A61B5/1075 ,  A61B6/0414 ,  A61B6/544 ,  A61B6/583 ,  G06F19/00

摘要： A method and an apparatus for estimating a geometric thickness of a breast in mammography/tomosynthesis or in other x-ray procedures, by imaging markers that are in the path of x-rays passing through the imaged object. The markings can be selected to be visible or to be invisible when the composite markings/breast image is viewed in clinical settings. If desired, the contribution of the markers to the image can be removed through further processing. The resulting information can be used determining the geometric thickness of the body being x-rayed and thus setting imaging parameters that are thickness-related, and for other purposes. The method and apparatus also have application in other types of x-ray imaging.

摘要翻译： 一种用于通过成像穿过成像对象的x射线路径中的标记来估计乳房X线照相术/断层合成或其他x射线程序中的乳房的几何厚度的方法和装置。 当在临床设置中观看复合标记/乳房图像时，标记可以被选择为可见或不可见。 如果需要，标记对图像的贡献可以通过进一步处理去除。 可以使用所得到的信息来确定被X射线的身体的几何厚度，从而设置与厚度相关的成像参数，并且用于其他目的。 该方法和装置也可用于其他类型的X射线成像。

公开(公告)号：US5426685A

公开(公告)日：1995-06-20

申请号：US185690

申请日：1994-01-24

申请人： Anthony J. Pellegrino ,  Milton Stoller ,  Kenneth F. DeFreitas ,  David D. Camarra ,  Anthony M. Scandura ,  Richard F. Schutz ,  Jeffrey R. Storm

发明人： Anthony J. Pellegrino ,  Milton Stoller ,  Kenneth F. DeFreitas ,  David D. Camarra ,  Anthony M. Scandura ,  Richard F. Schutz ,  Jeffrey R. Storm

IPC分类号： A61B6/00 ,  A61B6/04 ,  A61B10/00 ,  A61B10/02 ,  A61B19/00 ,  G01N23/201

CPC分类号： A61B6/502 ,  A61B6/0435 ,  A61B90/10 ,  A61B90/11 ,  A61B90/17 ,  A61B10/0233 ,  A61B6/4488

摘要： An elongated prone patient-supporting examining table for X-ray mammography is centrally supported at variable heights by a rear pedestal. The table is provided with a central breast-receiving aperture through which the patient's pendulant breast is exposed to a horizontal beam of X-rays from a tubehead source mounted on an arm angularly movable through an arc of some 210.degree. centered on the patient's breast. The patient's feet may be positioned at either end of the elongated table on an extensible footrest, permitting X-ray projection through more than 360.degree. around the patient's body. Diagnosis of suspect lesions and fine needle biopsy are both facilitated by stereotactic examination. Digital imaging using a CCD camera and image enhancement software provides magnification, contrast enhancement, window and level manipulation and high resolution images, with low exposure levels, short exposure times, and greatly reduced imaging times.

摘要翻译： 用于X射线乳房X线照相术的细长易患者支撑检查台由后基座在可变高度处集中支撑。 该台设置有中央乳房接收孔，通过该中心乳房接收孔，患者的侧枝乳房从安装在可以通过位于患者胸部上方的大约210度的弧的角度移动的臂上的管头源暴露于水平的X射线束。 患者的脚可以位于细长台的任一端在可伸展的脚踏板上，允许在患者身体周围超过360度的X射线投射。 通过立体定向检查有助于诊断疑似病变和细针穿刺活检。 使用CCD相机和图像增强软件的数字成像提供放大，对比度增强，窗口和电平操纵以及高分辨率图像，具有低曝光水平，短曝光时间，并大大缩短了成像时间。

公开(公告)号：US09308017B2

公开(公告)日：2016-04-12

申请号：US13611502

申请日：2012-09-12

申请人： John Girgenti ,  Kenneth F. DeFreitas ,  Thomas W. DeYoung

发明人： John Girgenti ,  Kenneth F. DeFreitas ,  Thomas W. DeYoung

IPC分类号： A61B10/00 ,  A61B17/34 ,  A61B10/02 ,  A61B19/00

CPC分类号： A61B90/17 ,  A61B5/062 ,  A61B5/065 ,  A61B10/0041 ,  A61B10/0275 ,  A61B17/3403 ,  A61B90/50 ,  A61B2010/0208 ,  A61B2017/3405 ,  A61B2090/376

摘要： A biopsy device includes a lateral member; a gun mount configured to support a biopsy gun, the gun mount being connected to the lateral member and movable along a first axis with respect to the lateral member, and a sensor which detects a position of the gun mount along the first axis with respect to the lateral member and generates positional data which is provided to an interface module. The gun mount can also be reconfigured in orientations which are offset in a dimension which is orthogonal to the first axis, orientations rotationally offset about the first axis or an axis parallel to the first axis. The lateral member can be in right hand and left hand orientations. Various sensors detect these reconfigurations and provide corresponding data to the interface module for additional calculations and display.

摘要翻译： 活检装置包括侧向构件; 枪支座，其构造成支撑活检枪，所述枪支座连接到所述横向构件并且可相对于所述侧向构件沿着第一轴线移动;以及传感器，其相对于所述第二轴线相对于所述第二轴线检测所述枪支座的位置 并且产生提供给接口模块的位置数据。 喷枪安装座还可以以与第一轴正交的尺寸偏移的取向重新配置，取向围绕第一轴线或平行于第一轴线的轴线旋转偏移。 侧向构件可以在右手和左手方向。 各种传感器检测这些重新配置，并将相应的数据提供给接口模块以进行额外的计算和显示。