公开(公告)号：US20070106251A1

公开(公告)日：2007-05-10

申请号：US11607172

申请日：2006-12-01

申请人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

发明人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

IPC分类号： A61M31/00

CPC分类号： A61L29/16 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/422 ,  A61M25/0084 ,  A61M25/10 ,  A61M37/00 ,  A61M37/0015 ,  A61M2025/0093 ,  A61M2025/0096 ,  A61M2025/1086

摘要： Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally along the blood vessel and in some cases to the adventitia surrounding other blood vessels.

摘要翻译： 用于将药剂递送到血管周围的外膜的方法和试剂盒利用具有微针的导管。 微针定位在血管周围空间中并且递送足够的周围渗透到血管周围的药剂的量，并且在许多情况下沿着血管纵向延伸，并且在一些情况下延伸到围绕其他血管的外膜。

公开(公告)号：US20070106250A1

公开(公告)日：2007-05-10

申请号：US11607169

申请日：2006-12-01

申请人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

发明人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

IPC分类号： A61M31/00

CPC分类号： A61L29/16 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/422 ,  A61M25/0084 ,  A61M25/10 ,  A61M37/00 ,  A61M37/0015 ,  A61M2025/0093 ,  A61M2025/0096 ,  A61M2025/1086

摘要： Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally along the blood vessel and in some cases to the adventitia surrounding other blood vessels.

公开(公告)号：US20070100320A1

公开(公告)日：2007-05-03

申请号：US11607170

申请日：2006-12-01

申请人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

发明人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

IPC分类号： A61M31/00 ,  A61M5/178 ,  B65D83/10

CPC分类号： A61L29/16 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/422 ,  A61M25/0084 ,  A61M25/10 ,  A61M37/00 ,  A61M37/0015 ,  A61M2025/0093 ,  A61M2025/0096 ,  A61M2025/1086

摘要： Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally along the blood vessel and in some cases to the adventitia surrounding other blood vessels.

摘要翻译： 用于将药剂递送到血管周围的外膜的方法和试剂盒利用具有微针的导管。 微针定位在血管周围空间中并且递送足够的周围渗透到血管周围的药剂的量，并且在许多情况下沿着血管纵向延伸，并且在一些情况下延伸到围绕其他血管的外膜。

公开(公告)号：US20070100319A1

公开(公告)日：2007-05-03

申请号：US11607167

申请日：2006-12-01

申请人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

发明人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

IPC分类号： A61M31/00 ,  A61M5/178 ,  B65D83/10

CPC分类号： A61L29/16 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/422 ,  A61M25/0084 ,  A61M25/10 ,  A61M37/00 ,  A61M37/0015 ,  A61M2025/0093 ,  A61M2025/0096 ,  A61M2025/1086

摘要： Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally along the blood vessel and in some cases to the adventitia surrounding other blood vessels.

公开(公告)号：US20070100318A1

公开(公告)日：2007-05-03

申请号：US11601290

申请日：2006-11-17

申请人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

发明人： Kirk Seward ,  Lynn Barr ,  Judith Wilber ,  Robert Cafferata

IPC分类号： A61M31/00

CPC分类号： A61L29/16 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/422 ,  A61M25/0084 ,  A61M25/10 ,  A61M37/00 ,  A61M37/0015 ,  A61M2025/0093 ,  A61M2025/0096 ,  A61M2025/1086

摘要： Methods and kits for delivering pharmaceutical agents to the adventitia surrounding a blood vessel utilize a catheter having a microneedle. The microneedle is positioned in the perivascular space and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally along the blood vessel and in some cases to the adventitia surrounding other blood vessels.