公开(公告)号：US20240341835A1

公开(公告)日：2024-10-17

申请号：US18757589

申请日：2024-06-28

申请人： HANGZHOU DEKE MEDTECH CO., LTD.

发明人： Nan Shao ,  Yang Li ,  Zhenping Zhuang ,  Fanbo Hu

IPC分类号： A61B18/14 ,  A61B18/00 ,  A61M25/00 ,  A61M25/06

CPC分类号： A61B18/1477 ,  A61B2018/00029 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61M2025/0079 ,  A61M25/0084 ,  A61M25/0097 ,  A61M25/0662

摘要： A sleeve includes a main body, the main body defines a first channel passing through the main body in an axial direction, and a side wall of the main body defines at least one second channel which is communicated with the first channel. When the sleeve abuts against the ventricular tissue wall, the fluid can only flow out from the second channel in the side wall of the sleeve, which means that the needle can be advanced for treatment of the ventricular tissue.

公开(公告)号：US12108982B2

公开(公告)日：2024-10-08

申请号：US17101729

申请日：2020-11-23

申请人： Ablative Solutions, Inc.

发明人： Andy Edward Denison ,  David R. Fischell ,  Tim A. Fischell ,  Darrin James Kent ,  Nicole Haratani

IPC分类号： A61B18/14 ,  A61B18/06 ,  A61B90/00 ,  A61B18/00 ,  A61B18/04 ,  A61M25/00 ,  A61M25/06

CPC分类号： A61B18/1492 ,  A61B18/06 ,  A61B18/1477 ,  A61B90/39 ,  A61B2018/00011 ,  A61B2018/00214 ,  A61B2018/00351 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00517 ,  A61B2018/00577 ,  A61B2018/046 ,  A61B2018/143 ,  A61B2018/1475 ,  A61B2090/376 ,  A61M25/0068 ,  A61M25/0074 ,  A61M25/0084 ,  A61M25/0662

摘要： An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple penetrators advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, nerve sensing, nerve stimulation, or ablation by application of energy. The catheter can include a proximal handle for the advancement of guide tubes and penetrators.

公开(公告)号：US20240307657A1

公开(公告)日：2024-09-19

申请号：US18615759

申请日：2024-03-25

申请人： Ablative Solutions, Inc.

发明人： David R. Fischell ,  Tim A. Fischell

IPC分类号： A61M25/00 ,  A61B5/283 ,  A61B17/22 ,  A61B18/00 ,  A61B18/06 ,  A61B18/14 ,  A61B90/00

CPC分类号： A61M25/0084 ,  A61B5/283 ,  A61B18/1492 ,  A61B90/39 ,  A61B2017/22038 ,  A61B2017/22068 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00285 ,  A61B2018/00375 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B18/06 ,  A61B2018/143 ,  A61B2018/1475 ,  A61B18/1477 ,  A61B2090/3966 ,  A61M2025/0087

摘要： At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium, or the aortic wall. The present invention also has an important application to ablate tissue around the ostium of one or both renal arteries, for the ablation of the sympathetic nerve fibers and/or other afferent or efferent nerves going to or from each kidney in order to treat hypertension.

公开(公告)号：US12090286B2

公开(公告)日：2024-09-17

申请号：US17454041

申请日：2021-11-08

申请人： Encompass Vascular, Inc.

发明人： Jean C. Orth ,  Richard S. Lilly ,  Eliot T. Kim ,  Zaya Tun ,  Robert G. Quintos

IPC分类号： A61M25/01 ,  A61F2/82 ,  A61F2/958 ,  A61L27/54 ,  A61M25/00 ,  A61M25/06 ,  A61M25/10

CPC分类号： A61M25/0155 ,  A61F2/82 ,  A61F2/958 ,  A61L27/54 ,  A61M25/005 ,  A61M25/0068 ,  A61M25/0082 ,  A61M25/0084 ,  A61M25/06 ,  A61F2250/0067 ,  A61M2025/0057 ,  A61M2025/0087 ,  A61M2025/018 ,  A61M2025/105 ,  A61M2025/1086 ,  A61M2205/0266

摘要： Medical devices and methods for delivering fluid. The medical devices include one or more needles for delivering fluid. The methods may include expanding an expandable member such as an inflatable member to expand an expandable scaffold outward toward a lumen wall.

公开(公告)号：US20240299075A1

公开(公告)日：2024-09-12

申请号：US18615753

申请日：2024-03-25

申请人： Ablative Solutions, Inc.

发明人： David R. Fischell ,  Tim A. Fischell ,  Robert Ryan Ragland ,  Darrin James Kent ,  Andy Edward Denison ,  Eric Thomas Johnson ,  Jeff Alan Burke ,  Christopher Scott Hayden

IPC分类号： A61B18/04 ,  A61B18/00 ,  A61B18/14 ,  A61B90/00 ,  A61M25/00 ,  A61M25/01 ,  A61M25/04 ,  A61M25/10

CPC分类号： A61B18/04 ,  A61B18/00 ,  A61B18/1477 ,  A61B90/37 ,  A61B90/39 ,  A61M25/0084 ,  A61M25/0108 ,  A61M25/04 ,  A61B2018/00166 ,  A61B2018/00285 ,  A61B2018/00351 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00547 ,  A61B2018/00577 ,  A61B2018/046 ,  A61B18/1492 ,  A61B2090/3735 ,  A61B2090/376 ,  A61B2090/3762 ,  A61B2090/378 ,  A61B2090/3782 ,  A61B2090/3966 ,  A61M2025/0087 ,  A61M25/1002

摘要： An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand with open ends around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system also includes means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The preferred embodiment of the catheter includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall.

公开(公告)号：US20240269373A1

公开(公告)日：2024-08-15

申请号：US18075377

申请日：2022-12-05

申请人： CLPH, LLC

发明人： Stephen A. Leeflang ,  Christian S. Eversull

IPC分类号： A61M5/14 ,  A61B34/20 ,  A61B90/00 ,  A61M5/00 ,  A61M5/145 ,  A61M5/158 ,  A61M5/20 ,  A61M25/00

CPC分类号： A61M5/1407 ,  A61B34/20 ,  A61M5/007 ,  A61M5/1452 ,  A61M5/158 ,  A61M25/0026 ,  A61M25/005 ,  A61M25/0084 ,  A61B2090/3966 ,  A61M5/14 ,  A61M2005/2013 ,  A61M2025/0089

摘要： Systems and methods are provided for injecting one or more agents into tissue within a patient's body. In one embodiment, an injection device includes a substantially axially incompressible elongate member including a lumen extending between proximal and distal ends thereof. A distal stop is provided on the distal end and a needle tip extends distally beyond the distal stop, the needle tip having a cross-section smaller than the distal end. The needle tip includes a passage communicating between the lumen and an outlet in the distal tip that has having a cross-section smaller than the lumen. In an exemplary embodiment, the elongate member includes a coil extending between the proximal and distal ends, and a sleeve disposed within an interior region of the coil extending between the proximal and distal ends. The sleeve defines the lumen and may be free-floating within at least a portion of the coil.

公开(公告)号：US20240261540A1

公开(公告)日：2024-08-08

申请号：US18467589

申请日：2023-09-14

申请人： Fractyl Health, Inc.

发明人： Harith Rajagopalan ,  Jay Caplan ,  R. Maxwell Flaherty ,  J. Christopher Flaherty

IPC分类号： A61M25/00 ,  A61F5/00 ,  A61K31/728 ,  A61K33/42 ,  A61K35/33 ,  A61K35/35 ,  A61K45/06 ,  A61L31/04 ,  A61L31/06 ,  A61L31/14 ,  A61L31/16 ,  A61M31/00 ,  A61N1/30

CPC分类号： A61M25/0084 ,  A61F5/0013 ,  A61F5/0076 ,  A61K31/728 ,  A61K33/42 ,  A61K35/33 ,  A61K35/35 ,  A61K45/06 ,  A61L31/043 ,  A61L31/048 ,  A61L31/06 ,  A61L31/145 ,  A61L31/16 ,  A61M25/00 ,  A61M25/0082 ,  A61M31/00 ,  A61F2005/0016 ,  A61M2025/0089 ,  A61M2025/0096 ,  A61N1/306

摘要： A system for treating a patient comprises a delivery device and injectate. The delivery device comprises an elongate shaft with a distal portion and at least one delivery element positioned on the elongate shaft distal portion. The delivery device is constructed and arranged to deliver the injectate through the at least one delivery element and into tissue to create a therapeutic restriction in the gastrointestinal tract. Methods of creating a therapeutic restriction are also provided.

公开(公告)号：US12053238B2

公开(公告)日：2024-08-06

申请号：US17127151

申请日：2020-12-18

申请人： Ablative Solutions, Inc.

发明人： David R. Fischell ,  Tim A. Fischell ,  Robert Ryan Ragland ,  Darrin James Kent ,  Andy Edward Denison ,  Eric Thomas Johnson ,  Jeff Alan Burke ,  Christopher Scott Hayden

IPC分类号： A61B18/14 ,  A61B5/0205 ,  A61B5/24 ,  A61B17/22 ,  A61B17/34 ,  A61B18/00 ,  A61B18/04 ,  A61B90/00 ,  A61M5/158 ,  A61M25/00 ,  A61M25/01 ,  A61M25/06

CPC分类号： A61B18/1492 ,  A61B17/3403 ,  A61B17/3478 ,  A61B18/04 ,  A61B18/1477 ,  A61B90/39 ,  A61M25/0084 ,  A61B5/0205 ,  A61B5/24 ,  A61B2017/22071 ,  A61B2018/00267 ,  A61B2018/00285 ,  A61B2018/00351 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00547 ,  A61B2018/00577 ,  A61B2018/046 ,  A61B2018/048 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/376 ,  A61B2090/3966 ,  A61M5/158 ,  A61M2025/0004 ,  A61M2025/0087 ,  A61M2025/0186 ,  A61M25/0662 ,  A61M2205/02 ,  A61M2205/32

摘要： An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

公开(公告)号：US20240225715A1

公开(公告)日：2024-07-11

申请号：US18614481

申请日：2024-03-22

申请人： Crossfire Medical Inc

发明人： Adam Tschida

IPC分类号： A61B18/06 ,  A61B18/00 ,  A61M25/00

CPC分类号： A61B18/06 ,  A61M25/0084 ,  A61B2018/00577 ,  A61B2018/00702

摘要： The disclosure includes a controller and a sheath having an open proximal sheath end coupled to the controller, an open distal sheath end configured for insertion into a vascular system of a patient, and a working lumen extending through the sheath. The system may include a wire extending from the controller through the working lumen, the wire having a distal wire end configured to mechanically treat a vessel wall of a treatment segment, a length of the distal wire end defining a length of the treatment segment. The working lumen may be configured to slidably receive the wire and allow for a passage of a fluid about the wire therethrough to chemically treat the treatment segment. When the system receives a first input the distal wire end may mechanically treat the vessel wall. When the system receives a second input and/or a third input, the system may deliver the fluid.

公开(公告)号：US20240164824A1

公开(公告)日：2024-05-23

申请号：US18427612

申请日：2024-01-30

申请人： Crossfire Medical Inc

发明人： Adam Tschida

IPC分类号： A61B18/06 ,  A61M25/00 ,  A61B18/00

CPC分类号： A61B18/06 ,  A61M25/0084 ,  A61B2018/00577 ,  A61B2018/00702

摘要： The disclosure includes a controller and a sheath having an open proximal sheath end coupled to the controller, an open distal sheath end configured for insertion into a vascular system of a patient, and a working lumen extending through the sheath. The system may include a wire extending from the controller through the working lumen, the wire having a distal wire end configured to mechanically treat a vessel wall of a treatment segment, a length of the distal wire end defining a length of the treatment segment. The working lumen may be configured to slidably receive the wire and allow for a passage of a fluid about the wire therethrough to chemically treat the treatment segment. When the system receives a first input the distal wire end may mechanically treat the vessel wall. When the system receives a second input and/or a third input, the system may deliver the fluid.