公开(公告)号：US12226743B2

公开(公告)日：2025-02-18

申请号：US18060728

申请日：2022-12-01

Applicant: Life Technologies Corporation

Inventor： Clinton C. Staheli ,  Brandon M. Knudsen ,  Trevor G. Williams ,  Steven R. Kjar

IPC: B01F27/054 ,  B01F27/07 ,  B01F27/072 ,  B01F27/1125 ,  B01F27/191 ,  B01F27/21 ,  B01F27/2111 ,  B01F27/88 ,  B01F27/906 ,  B01F35/41 ,  B01F35/513 ,  C12M1/00 ,  C12M1/06

Abstract: A method of mixing a fluid includes at least partially unfolding a collapsible bag bounding a compartment, the collapsible bag containing in the compartment at least a portion of an elongated drive line or drive shaft and an impeller secured to the drive line or drive shaft, the impeller including a plurality of impeller blades that are pivotable relative to the drive line or drive shaft, at least one of the plurality of impeller blades being in a collapsed position. A fluid is delivered into the compartment of the collapsible bag. The drive line or drive shaft is then rotated so as to rotate the impeller within the compartment and mix the fluid therein, the at least one of the plurality of impeller blades pivoting from the collapsed position to an expanded position as the impeller is rotated within the compartment.

公开(公告)号：US20190282983A1

公开(公告)日：2019-09-19

申请号：US16421168

申请日：2019-05-23

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Trevor G. Williams

IPC: B01F15/00 ,  B01F7/00

Abstract: A method for operating a bioreactor includes passing a drive shaft into a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within a container, the first tubular connector being more flexible than the second tubular connector, the second tubular connector having a length that comprises at least 20% of a combined length of the first tubular connector and the second tubular connector. Rotating the drive shaft so as to rotate the first tubular connector and the second tubular connector within the container.

公开(公告)号：US09855537B2

公开(公告)日：2018-01-02

申请号：US14660405

申请日：2015-03-17

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Trevor G. Williams

IPC: B01F7/00 ,  B01F15/00

CPC classification number: B01F15/00681 ,  B01F7/001 ,  B01F7/00675 ,  B01F7/00691 ,  B01F15/0085 ,  B01F2215/0073

Abstract: A fluid mixing system includes a flexible bag having an interior surface bounding a compartment. An elongated first tubular connector is disposed within the compartment of the flexible bag, the first tubular connector having a first end and an opposing second end, the first end of the first tubular connector being coupled with the flexible bag. An elongated second tubular connector is disposed within the compartment of the flexible bag, the second tubular connector being more rigid than the first tubular connector and having a first end coupled to the second end of the first tubular connector. A plurality of impeller are disposed on the elongated second tubular connector at spaced apart locations.

公开(公告)号：US20150265988A1

公开(公告)日：2015-09-24

申请号：US14660405

申请日：2015-03-17

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Trevor G. Williams

IPC: B01F15/00

CPC classification number: B01F15/00681 ,  B01F7/001 ,  B01F7/00675 ,  B01F7/00691 ,  B01F15/0085 ,  B01F2215/0073

Abstract: A fluid mixing system includes a flexible bag having an interior surface bounding a compartment. An elongated first tubular connector is disposed within the compartment of the flexible bag, the first tubular connector having a first end and an opposing second end, the first end of the first tubular connector being coupled with the flexible bag. An elongated second tubular connector is disposed within the compartment of the flexible bag, the second tubular connector being more rigid than the first tubular connector and having a first end coupled to the second end of the first tubular connector. A plurality of impeller are disposed on the elongated second tubular connector at spaced apart locations.

Abstract translation: 流体混合系统包括具有包围隔室的内表面的柔性袋。 细长的第一管状连接器设置在柔性袋的隔室内，第一管状连接器具有第一端和相对的第二端，第一管状连接器的第一端与柔性袋结合。 细长的第二管状连接器设置在柔性袋的隔室内，第二管状连接器比第一管状连接器更刚性，并且具有联接到第一管状连接器的第二端的第一端。 多个叶轮在间隔开的位置设置在细长的第二管状连接器上。