公开(公告)号：US20240261742A1

公开(公告)日：2024-08-08

申请号：US18106282

申请日：2023-02-06

Applicant: Parker-Hannifin Corporation

Inventor： Brendan J. Schuler

IPC: B01F27/1152 ,  B01F27/1151 ,  B01F27/191 ,  B01F27/2111 ,  B01F27/2124

CPC classification number: B01F27/1152 ,  B01F27/1151 ,  B01F27/191 ,  B01F27/2111 ,  B01F27/2124

Abstract: A modular mixing impeller assembly that includes one or more connection tubes, and one or more impellers configured for assembly to the one or more connection tubes. Each of the one or more impellers has a plurality of mixing blades. Each of the one or more impellers is assembled onto at least one connection tube via a friction fit such that each of the one or more impellers is configured to rotate with its attached connection tube, and wherein the assembly between impeller and connection tube creates an airtight and water-tight seal.

公开(公告)号：US12226743B2

公开(公告)日：2025-02-18

申请号：US18060728

申请日：2022-12-01

Applicant: Life Technologies Corporation

Inventor： Clinton C. Staheli ,  Brandon M. Knudsen ,  Trevor G. Williams ,  Steven R. Kjar

IPC: B01F27/054 ,  B01F27/07 ,  B01F27/072 ,  B01F27/1125 ,  B01F27/191 ,  B01F27/21 ,  B01F27/2111 ,  B01F27/88 ,  B01F27/906 ,  B01F35/41 ,  B01F35/513 ,  C12M1/00 ,  C12M1/06

Abstract: A method of mixing a fluid includes at least partially unfolding a collapsible bag bounding a compartment, the collapsible bag containing in the compartment at least a portion of an elongated drive line or drive shaft and an impeller secured to the drive line or drive shaft, the impeller including a plurality of impeller blades that are pivotable relative to the drive line or drive shaft, at least one of the plurality of impeller blades being in a collapsed position. A fluid is delivered into the compartment of the collapsible bag. The drive line or drive shaft is then rotated so as to rotate the impeller within the compartment and mix the fluid therein, the at least one of the plurality of impeller blades pivoting from the collapsed position to an expanded position as the impeller is rotated within the compartment.

公开(公告)号：US12214324B2

公开(公告)日：2025-02-04

申请号：US18353754

申请日：2023-07-17

Applicant: Life Technologies Corporation

Inventor： Jeffery C. Hurd ,  Nephi D. Jones ,  Jacob D. Lee

IPC: B01F27/231 ,  B01F23/231 ,  B01F27/07 ,  B01F27/113 ,  B01F27/2111 ,  B01F27/2121 ,  B01F27/2122 ,  B01F27/213 ,  B01F33/00 ,  B01F35/513 ,  C12M1/00 ,  C12M1/06 ,  C12M1/34 ,  B01F101/22 ,  B01F101/44

Abstract: A liquid mixing system includes a support housing at least partially bounding a compartment. A mount is secured to the support housing. A drive motor assembly is configured to engage a drive shaft for moving the drive shaft within the compartment of the support housing. A four bar linkage system extends between the mount and the drive motor assembly, the four bar linkage system being movable between a first position wherein the drive motor assembly is disposed at a first elevation and a second position wherein the drive motor assembly is disposed at a second elevation that is different from the first elevation.

公开(公告)号：US12128371B2

公开(公告)日：2024-10-29

申请号：US16358263

申请日：2019-03-19

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Clinton C. Staheli ,  Brandon M. Knudsen ,  Trevor G. Williams ,  Steven R. Kjar

IPC: B01F27/054 ,  B01F27/07 ,  B01F27/072 ,  B01F27/1125 ,  B01F27/191 ,  B01F27/21 ,  B01F27/2111 ,  B01F27/88 ,  B01F27/906 ,  B01F35/41 ,  B01F35/513 ,  C12M1/00 ,  C12M1/06

CPC classification number: B01F27/212 ,  B01F27/0541 ,  B01F27/071 ,  B01F27/0726 ,  B01F27/1125 ,  B01F27/11253 ,  B01F27/191 ,  B01F27/2111 ,  B01F27/88 ,  B01F27/906 ,  B01F35/41 ,  B01F35/4111 ,  B01F35/4121 ,  B01F35/513 ,  C12M23/14 ,  C12M23/52 ,  C12M27/02

Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, can be coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.

公开(公告)号：US20230356158A1

公开(公告)日：2023-11-09

申请号：US18353754

申请日：2023-07-17

Applicant: Life Technologies Corporation

Inventor： Jeffery C. HURD ,  Nephi D. Jones ,  Jacob D. Lee

IPC: B01F27/231 ,  C12M1/34 ,  C12M1/00 ,  B01F23/231 ,  B01F27/07 ,  B01F27/113 ,  B01F27/213 ,  B01F27/2111 ,  B01F27/2121 ,  B01F27/2122 ,  B01F33/00 ,  B01F35/513 ,  C12M1/06

CPC classification number: B01F27/2312 ,  C12M41/44 ,  C12M23/26 ,  B01F23/2311 ,  B01F27/071 ,  B01F27/113 ,  B01F27/213 ,  B01F27/2111 ,  B01F27/2121 ,  B01F27/2122 ,  B01F33/86 ,  B01F35/513 ,  C12M23/14 ,  C12M27/02 ,  B01F23/231151 ,  B01F2101/22

Abstract: A liquid mixing system includes a support housing at least partially bounding a compartment. A mount is secured to the support housing. A drive motor assembly is configured to engage a drive shaft for moving the drive shaft within the compartment of the support housing. A four bar linkage system extends between the mount and the drive motor assembly, the four bar linkage system being movable between a first position wherein the drive motor assembly is disposed at a first elevation and a second position wherein the drive motor assembly is disposed at a second elevation that is different from the first elevation.

公开(公告)号：US20230294054A1

公开(公告)日：2023-09-21

申请号：US18297504

申请日：2023-04-07

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Trevor G. WILLIAMS

IPC: B01F35/41 ,  C12M1/02 ,  C12M1/00 ,  C12M1/10 ,  B01F27/07 ,  B01F27/2111 ,  B01F27/2121 ,  B01F35/513

CPC classification number: B01F35/4111 ,  C12M1/02 ,  C12M1/007 ,  C12M1/10 ,  B01F27/071 ,  B01F27/2111 ,  B01F27/2121 ,  B01F35/513 ,  B01F2101/44

Abstract: A method for operating a bioreactor includes passing a drive shaft into a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within a container, the first tubular connector being more flexible than the second tubular connector, the second tubular connector having a length that comprises at least 20% of a combined length of the first tubular connector and the second tubular connector. Rotating the drive shaft so as to rotate the first tubular connector and the second tubular connector within the container.

公开(公告)号：US11745151B2

公开(公告)日：2023-09-05

申请号：US17125556

申请日：2020-12-17

Applicant: Life Technologies Corporation

Inventor： Jeffery C. Hurd ,  Nephi D. Jones ,  Jacob D. Lee

IPC: B01F7/00 ,  C12M1/34 ,  C12M1/00 ,  B01F3/04 ,  B01F15/00 ,  B01F27/231 ,  B01F23/231 ,  B01F27/07 ,  B01F27/113 ,  B01F27/213 ,  B01F27/2111 ,  B01F27/2121 ,  B01F27/2122 ,  B01F33/00 ,  B01F35/513 ,  C12M1/06 ,  B01F101/22 ,  B01F101/44

CPC classification number: B01F27/2312 ,  B01F23/2311 ,  B01F27/071 ,  B01F27/113 ,  B01F27/213 ,  B01F27/2111 ,  B01F27/2121 ,  B01F27/2122 ,  B01F33/86 ,  B01F35/513 ,  C12M23/14 ,  C12M23/26 ,  C12M27/02 ,  C12M41/44 ,  B01F23/231151 ,  B01F2101/22 ,  B01F2101/44

Abstract: A liquid mixing system includes a support housing at least partially bounding a compartment. A mount is secured to the support housing. A drive motor assembly is configured to engage a drive shaft for moving the drive shaft within the compartment of the support housing. A four bar linkage system extends between the mount and the drive motor assembly, the four bar linkage system being movable between a first position wherein the drive motor assembly is disposed at a first elevation and a second position wherein the drive motor assembly is disposed at a second elevation that is different from the first elevation.

公开(公告)号：US20240376418A1

公开(公告)日：2024-11-14

申请号：US18780337

申请日：2024-07-22

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Nephi D. Jones ,  Christopher D. Brau

IPC: C12M1/06 ,  B01F27/1111 ,  B01F27/191 ,  B01F27/2111 ,  B01F35/41 ,  B01F35/513 ,  B01F101/44 ,  C12M1/00 ,  C12M1/02 ,  C12N1/00

Abstract: A fluid mixing system includes a collapsible container bounding a compartment and extending between a first end and an opposing second end. An elongated continuous drive line is at least partially disposed within the compartment of the container. A first portion of the drive line is laterally spaced apart from a second portion of the drive line, and the first portion of the drive line and the second portion of the drive line are rotatable within the compartment of the container.

公开(公告)号：US12077742B2

公开(公告)日：2024-09-03

申请号：US16853865

申请日：2020-04-21

Applicant: Life Technologies Corporation

Inventor： Nephi D. Jones ,  Christopher D. Brau

IPC: C12M1/06 ,  B01F27/1111 ,  B01F27/191 ,  B01F27/2111 ,  B01F35/41 ,  B01F35/513 ,  B01F101/44 ,  C12M1/00 ,  C12M1/02 ,  C12N1/00

CPC classification number: C12M27/02 ,  B01F27/1111 ,  B01F27/191 ,  B01F27/2111 ,  B01F35/4121 ,  B01F35/513 ,  C12M1/007 ,  C12M1/02 ,  C12M23/14 ,  C12N1/00 ,  B01F2101/44

Abstract: A method for mixing a biological suspension includes disposing a biological suspension within a compartment of a container, the biological suspension comprising cells or microorganisms suspended within a nutrient growth medium; and rotating a first drive line and laterally spaced apart second drive line within the compartment of the container so as to cause the drive lines to twist into a helical configuration and mix the biological suspension.

公开(公告)号：US11654408B2

公开(公告)日：2023-05-23

申请号：US16421168

申请日：2019-05-23

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Trevor G. Williams

IPC: B01F27/2111 ,  B01F35/513 ,  B01F35/41 ,  C12M1/02 ,  C12M1/00 ,  C12M1/10 ,  B01F27/07 ,  B01F27/2121 ,  B01F101/44

CPC classification number: B01F35/4111 ,  B01F27/071 ,  B01F27/2111 ,  B01F27/2121 ,  B01F35/513 ,  C12M1/007 ,  C12M1/02 ,  C12M1/10 ,  B01F2101/44

Abstract: A method for operating a bioreactor includes passing a drive shaft into a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within a container, the first tubular connector being more flexible than the second tubular connector, the second tubular connector having a length that comprises at least 20% of a combined length of the first tubular connector and the second tubular connector. Rotating the drive shaft so as to rotate the first tubular connector and the second tubular connector within the container.