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公开(公告)号：US11654408B2
公开(公告)日：2023-05-23
申请号：US16421168
申请日：2019-05-23
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Trevor G. Williams
IPC: B01F27/2111 , B01F35/513 , B01F35/41 , C12M1/02 , C12M1/00 , C12M1/10 , B01F27/07 , B01F27/2121 , B01F101/44
CPC classification number: B01F35/4111 , B01F27/071 , B01F27/2111 , B01F27/2121 , B01F35/513 , C12M1/007 , C12M1/02 , C12M1/10 , B01F2101/44
Abstract: A method for operating a bioreactor includes passing a drive shaft into a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within a container, the first tubular connector being more flexible than the second tubular connector, the second tubular connector having a length that comprises at least 20% of a combined length of the first tubular connector and the second tubular connector. Rotating the drive shaft so as to rotate the first tubular connector and the second tubular connector within the container.
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公开(公告)号：US20230093549A1
公开(公告)日：2023-03-23
申请号：US18060728
申请日：2022-12-01
Applicant: Life Technologies Corporation
Inventor： Clinton C. Staheli , Brandon M. Knudsen , Trevor G. Williams , Steven R. Kjar
IPC: B01F27/21 , C12M1/00 , C12M1/06 , B01F27/07 , B01F27/88 , B01F27/191 , B01F27/054 , B01F27/072 , B01F27/906 , B01F27/1125 , B01F27/2111 , B01F35/41 , B01F35/513
Abstract: A method of mixing a fluid includes at least partially unfolding a collapsible bag bounding a compartment, the collapsible bag containing in the compartment at least a portion of an elongated drive line or drive shaft and an impeller secured to the drive line or drive shaft, the impeller including a plurality of impeller blades that are pivotable relative to the drive line or drive shaft, at least one of the plurality of impeller blades being in a collapsed position. A fluid is delivered into the compartment of the collapsible bag. The drive line or drive shaft is then rotated so as to rotate the impeller within the compartment and mix the fluid therein, the at least one of the plurality of impeller blades pivoting from the collapsed position to an expanded position as the impeller is rotated within the compartment.
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公开(公告)号：US20180071700A1
公开(公告)日：2018-03-15
申请号：US15803327
申请日：2017-11-03
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Clinton C. Staheli , Brandon M. Knudsen , Trevor G. Williams , Steven R. Kjar
CPC classification number: B01F7/00683 , B01F7/00058 , B01F7/001 , B01F7/00158 , B01F7/00291 , B01F7/00316 , B01F7/00633 , B01F7/00675 , B01F7/1695 , B01F7/20 , B01F15/00668 , B01F15/00681 , B01F15/00707 , B01F15/0085 , C12M23/14 , C12M23/52 , C12M27/02
Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, can be coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.
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公开(公告)号：US10335751B2
公开(公告)日：2019-07-02
申请号：US15829379
申请日：2017-12-01
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Trevor G. Williams
Abstract: A bioreactor includes a flexible container and an impeller assembly having a hollow tube. The impeller assembly is coupled to the flexible container. At least one mixing element is removably disposed on the hollow tube. A drive shaft is adapted to engage the hollow tube of the impeller assembly and facilitate rotational movement of the hollow tube.
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公开(公告)号：US20180078915A1
公开(公告)日：2018-03-22
申请号：US15829379
申请日：2017-12-01
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Trevor G. Williams
CPC classification number: B01F15/00681 , B01F7/001 , B01F7/00675 , B01F7/00691 , B01F15/0085 , B01F2215/0073
Abstract: A bioreactor includes a flexible container and an impeller assembly having a hollow tube. The impeller assembly is coupled to the flexible container. At least one mixing element is removably disposed on the hollow tube. A drive shaft is adapted to engage the hollow tube of the impeller assembly and facilitate rotational movement of the hollow tube.
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Patent Agency Ranking
公开(公告)号：US20150117142A1
公开(公告)日：2015-04-30
申请号：US14390956
申请日：2013-03-14
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Clinton C. Staheli , Brandon M. Knudsen , Trevor G. Williams , Steven R. Kjar
CPC classification number: B01F7/00683 , B01F7/00058 , B01F7/001 , B01F7/00158 , B01F7/00291 , B01F7/00316 , B01F7/00633 , B01F7/00675 , B01F7/1695 , B01F7/20 , B01F15/00668 , B01F15/00681 , B01F15/00707 , B01F15/0085 , C12M23/14 , C12M23/52 , C12M27/02
Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, is coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.
Abstract translation: 流体混合系统包括围绕隔室的容器，例如柔性袋。 柔性驱动线设置在隔室内，驱动线具有可旋转地连接到容器的第一端的第一端和可旋转地连接到容器的第二端的相对的第二端。 至少一个混合元件，例如叶轮，与柔性驱动线连接。 驱动线的旋转有利于在容器内旋转叶轮。
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公开(公告)号：US12128371B2
公开(公告)日：2024-10-29
申请号：US16358263
申请日：2019-03-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Clinton C. Staheli , Brandon M. Knudsen , Trevor G. Williams , Steven R. Kjar
IPC: B01F27/054 , B01F27/07 , B01F27/072 , B01F27/1125 , B01F27/191 , B01F27/21 , B01F27/2111 , B01F27/88 , B01F27/906 , B01F35/41 , B01F35/513 , C12M1/00 , C12M1/06
CPC classification number: B01F27/212 , B01F27/0541 , B01F27/071 , B01F27/0726 , B01F27/1125 , B01F27/11253 , B01F27/191 , B01F27/2111 , B01F27/88 , B01F27/906 , B01F35/41 , B01F35/4111 , B01F35/4121 , B01F35/513 , C12M23/14 , C12M23/52 , C12M27/02
Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, can be coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.
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公开(公告)号：US20190209981A1
公开(公告)日：2019-07-11
申请号：US16358263
申请日：2019-03-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Clinton C. Staheli , Brandon M. Knudsen , Trevor G. Williams , Steven R. Kjar
CPC classification number: B01F7/00683 , B01F7/00058 , B01F7/001 , B01F7/00158 , B01F7/00291 , B01F7/00316 , B01F7/00633 , B01F7/00675 , B01F7/1695 , B01F7/20 , B01F15/00668 , B01F15/00681 , B01F15/00707 , B01F15/0085 , C12M23/14 , C12M23/52 , C12M27/02
Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, can be coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.
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公开(公告)号：US10272400B2
公开(公告)日：2019-04-30
申请号：US15803327
申请日：2017-11-03
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Clinton C. Staheli , Brandon M. Knudsen , Trevor G. Williams , Steven R. Kjar
Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, can be coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.
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公开(公告)号：US09839886B2
公开(公告)日：2017-12-12
申请号：US14390956
申请日：2013-03-14
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Clinton C. Staheli , Brandon M. Knudsen , Trevor G. Williams , Steven R. Kjar
CPC classification number: B01F7/00683 , B01F7/00058 , B01F7/001 , B01F7/00158 , B01F7/00291 , B01F7/00316 , B01F7/00633 , B01F7/00675 , B01F7/1695 , B01F7/20 , B01F15/00668 , B01F15/00681 , B01F15/00707 , B01F15/0085 , C12M23/14 , C12M23/52 , C12M27/02
Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, is coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.
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