公开(公告)号：US20100265252A1

公开(公告)日：2010-10-21

申请号：US12808398

申请日：2008-12-16

申请人： Helko Lehmann ,  Juergen Weese ,  Dieter Geller

发明人： Helko Lehmann ,  Juergen Weese ,  Dieter Geller

IPC分类号： G06T17/00

CPC分类号： G06T15/08

摘要： The invention relates to a system (100) for visualizing an image data set comprising a plurality of voxels, using a ray casting method, each voxel of the plurality of voxels belonging to at least one class, each class of the at least one class being associated with an intensity redistribution function for computing a redefined voxel value of a voxel from a measured voxel value of said voxel, the system comprising a sampling unit (120) for computing a sample value at a sample location on a projection ray cast from an image pixel, based on a redefined voxel value of at least one voxel proximal to the sample location on the projection ray, wherein the redefined voxel value of the at least one voxel is computed from a measured voxel value of the at least one voxel, using the intensity redistribution function associated with the at least one class of the at least one voxel.

摘要翻译： 本发明涉及一种用于使用射线投射方法来可视化包括多个体素的图像数据集的系统（100），所述多个体素的每个体素属于至少一个类，所述至少一个类的每个类别 与用于从所述体素的测量的体素值计算体素的重新定义的体素值的强度再分布函数相关联，所述体素包括用于计算从图像投射的投影光线上的样本位置处的样本值的采样单元（120） 基于近似于投影射线上的样本位置的至少一个体素的重新定义的体素值，其中根据所述至少一个体素的测量体素值计算所述至少一个体素的重新定义的体素值，其使用 强度再分配功能与至少一个类别的至少一个体素相关联。

公开(公告)号：US09750465B2

公开(公告)日：2017-09-05

申请号：US13514312

申请日：2010-12-08

申请人： Klaus Juergen Engel ,  Dieter Geller ,  Gereon Vogtmeier ,  Thomas Koehler

发明人： Klaus Juergen Engel ,  Dieter Geller ,  Gereon Vogtmeier ,  Thomas Koehler

IPC分类号： A61B6/00 ,  A61B6/03

CPC分类号： A61B6/00 ,  A61B6/032 ,  A61B6/4291 ,  A61B6/484 ,  A61B6/488 ,  A61B6/5241

摘要： The invention relates to the field of X-ray differential phase contrast imaging. For scanning large objects and for an improved contrast to noise ratio, an X-ray device (10) for imaging an object (18) is provided. The X-ray device (10) comprises an X-ray emitter arrangement (12) and an X-ray detector arrangement (14), wherein the X-ray emitter arrangement (14) is adapted to emit an X-ray beam (16) through the object (18) onto the X-ray detector arrangement (14). The X-ray beam (16) is at least partial spatial coherent and fan-shaped. The X-ray detector arrangement (14) comprises a phase grating (50) and an absorber grating (52). The X-ray detector arrangement (14) comprises an area detector (54) for detecting X-rays, wherein the X-ray device is adapted to generate image data from the detected X-rays and to extract phase information from the X-ray image data, the phase information relating to a phase shift of X-rays caused by the object (18). The object (18) has a region of interest (32) which is larger than a detection area of the X-ray detector (18) and the X-ray device (10) is adapted to generate image data of the region of interest (32) by moving the object (18) and the X-ray detector arrangement (14) relative to each other.

公开(公告)号：US09084528B2

公开(公告)日：2015-07-21

申请号：US13514682

申请日：2010-12-03

申请人： Dieter Geller ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Thomas Koehler ,  Ewald Roessl

发明人： Dieter Geller ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Thomas Koehler ,  Ewald Roessl

IPC分类号： G01N23/04 ,  A61B6/00

CPC分类号： A61B6/00 ,  A61B6/4291 ,  A61B6/4441 ,  A61B6/484

摘要： X-ray devices for Phase Contrast Imaging (PCI) are often built up with the help of gratings. For large field-of-views (FOV), production cost and complexity of these gratings could increase significantly as they need to have a focused geometry. Instead of a pure PCI with a large FOV, this invention suggests to combine a traditional absorption X-ray-imaging system with large-FOV with an insertable low-cost PCI system with small-FOV, The invention supports the user to direct the PCI system with reduced FOV to a region that he regards as most interesting for performing a PCI scan thus eliminating X-ray dose exposure for scanning regions not interesting for a radiologist. The PCI scan may be generated on the basis of local tomography.

摘要翻译： 用于相位对比成像（PCI）的X射线装置通常在光栅的帮助下构建。 对于大视野（FOV）来说，这些光栅的生产成本和复杂性可能会因为需要聚焦几何而显着增加。 本发明不是采用具有大FOV的纯PCI，而是将传统的吸收X射线成像系统与大型FOV结合，并具有小FOV的可插入低成本PCI系统。本发明支持用户指导PCI 系统将FOV降低到他认为对于执行PCI扫描最有趣的区域，从而消除了用于放射科医生不感兴趣的扫描区域的X射线剂量曝光。 可以基于局部断层摄影产生PCI扫描。

公开(公告)号：US09066649B2

公开(公告)日：2015-06-30

申请号：US13514383

申请日：2010-12-03

申请人： Ewald Roessl ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Dieter Geller ,  Gerhard Martens ,  Sebastian Siegmund Schusser ,  Thomas Koehler

发明人： Ewald Roessl ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Dieter Geller ,  Gerhard Martens ,  Sebastian Siegmund Schusser ,  Thomas Koehler

IPC分类号： A61B6/00 ,  A61B6/03

CPC分类号： A61B6/00 ,  A61B6/032 ,  A61B6/4021 ,  A61B6/4092 ,  A61B6/4291 ,  A61B6/484

摘要： An X-ray image acquisition apparatus employing phase-contrast imaging with enlarged field of view includes an X-ray source, an X-ray detector element having a detector size, a beam splitter grating and an analyzer grating. An object is arrangeable between the X-ray source and detector. The beam splitter grating and the analyzer grating are arrangeable between the X-ray source and detector. The X-ray source, the beam splitter grating, the analyzer grating and the X-ray detector are operatively coupled such that a phase-contrast image of the object is obtainable. The apparatus is configure to acquire a phase-contrast image having a field of view larger than the detector size. The X-ray detector element is displaceable where, by the displacement of the X-ray detector, a phase-contrast image of the enlarged field of view is obtainable.

摘要翻译： 采用具有放大视场的相位对比成像的X射线图像获取装置包括X射线源，具有检测器尺寸的X射线检测器元件，分束器光栅和分析器光栅。 X射线源和检测器之间可以配置一个物体。 分束器光栅和分析器光栅可以在X射线源和检测器之间布置。 X射线源，分束器光栅，分析器光栅和X射线检测器可操作地耦合，使得可以获得物体的相差图像。 该装置被配置为获取具有大于检测器尺寸的视场的相位对比度图像。 X射线检测器元件可移动，其中通过X射线检测器的位移可以获得放大视场的相位对比图像。

公开(公告)号：US20080208578A1

公开(公告)日：2008-08-28

申请号：US11575703

申请日：2005-09-13

申请人： Dieter Geller

发明人： Dieter Geller

IPC分类号： G10L15/06

CPC分类号： G10L15/07 ,  G10L15/063 ,  G10L15/144 ,  G10L15/20

摘要： The present invention provides a method of incorporating speaker-dependent expressions into a speaker-independent speech recognition system providing training data for a plurality of environmental conditions and for a plurality of speakers. The speakerdependent expression is transformed in a sequence of feature vectors and a mixture density of the set of speaker-independent training data is determined that has a minimum distance to the generated sequence of feature vectors. The determined mixture density is then assigned to a Hidden-Markov-Model (HMM) state of the speaker-dependent expression. Therefore, speaker-dependent training data and references no longer have to be explicitly stored in the speech recognition system. Moreover, by representing a speaker-dependent expression by speaker-independent training data, an environmental adaptation is inherently provided. Additionally, the invention provides generation of artificial feature vectors on the basis of the speaker-dependent expression providing a substantial improvement for the robustness of the speech recognition system with respect to varying environmental conditions.

摘要翻译： 本发明提供了一种将说话者依赖表达结合到与多个环境条件和多个扬声器提供训练数据的与说话者无关的语音识别系统中。 说话者依赖的表达式被转换成特征向量序列，并且确定与所生成的特征向量序列具有最小距离的与说话者无关的训练数据集合的混合密度。 然后将确定的混合密度分配给说话者依赖表达的隐马尔可夫模型（HMM）状态。 因此，说话者相关的训练数据和参考文献不再必须明确地存储在语音识别系统中。 此外，通过用与说话者无关的训练数据表示说话者依赖表达，固有地提供了环境适应。 此外，本发明提供了基于说话者依赖表达的人造特征向量的生成，为语音识别系统相对于变化的环境条件的鲁棒性提供了显着的改进。

公开(公告)号：US20070124143A1

公开(公告)日：2007-05-31

申请号：US10574447

申请日：2004-10-05

申请人： Dieter Geller

发明人： Dieter Geller

IPC分类号： G10L15/00

CPC分类号： G10L15/065 ,  G10L15/20

摘要： The present invention relates to a method, a system and a computer program product for speech recognition with environmental adaptation. Feature vectors being descriptive of a power spectrum of incorming speech are transformed in order to eliminate environmental mismatch between the recording conditions of training speech and the recording conditions of the speech being subject to speech recognition. The method is based on a probability whether a received sound interval represents speech or a speech discontinuity. Determining mean values for sound intervals representing speech or speech discontinuity and comparing said values with respective values of the training data, a transformation of generated feature vectors can be performed in order to reduce the environmental mismatch.

摘要翻译： 本发明涉及一种用于具有环境适应性的语音识别的方法，系统和计算机程序产品。 对描述发音语音的功率谱的特征向量进行变换，以消除训练语音的记录条件与正在进行语音识别的语音的记录条件之间的环境不匹配。 该方法基于接收到的声音间隔是表示语音还是语音不连续性的概率。 确定表示语音或语音不连续性的声音间隔的平均值，并将所述值与训练数据的相应值进行比较，可以执行生成的特征向量的变换，以减少环境不匹配。

公开(公告)号：US09754411B2

公开(公告)日：2017-09-05

申请号：US12676641

申请日：2008-09-11

申请人： Dieter Geller ,  Helko Lehmann

发明人： Dieter Geller ,  Helko Lehmann

IPC分类号： G06T15/08 ,  G06T19/00 ,  G06T11/00

CPC分类号： G06T19/00 ,  G06T11/003 ,  G06T15/08

摘要： The invention relates to a system (100) for visualizing an object of interest comprised in a volume of an image dataset, the system comprising a path unit (110) for specifying a path in the volume of the image dataset on the basis of the object of interest, a location unit (120) for determining a location on a projection ray through the volume of the image dataset on the basis of the specified path, and a value unit (130) for computing a projected gray value corresponding to the projection rayon the basis of the determined location on the projection ray. Because the locations on the projection ray are determined based on the specified path for indicating the object of interest, the actual computation of the projection gray values may be designed and constructed to show gray values describing the object of interest while hiding gray values describing other objects, in particular occluding objects. Thus, the system of the invention is arranged for visualizing the object of interest at different viewing angles without occluding the object of interest.

公开(公告)号：US20120307966A1

公开(公告)日：2012-12-06

申请号：US13514383

申请日：2010-12-03

申请人： Ewald Roessl ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Dieter Geller ,  Gerhard Martens ,  Sabastian Siegmund Schusser ,  Thomas Koehler

发明人： Ewald Roessl ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Dieter Geller ,  Gerhard Martens ,  Sabastian Siegmund Schusser ,  Thomas Koehler

IPC分类号： G01N23/04

CPC分类号： A61B6/00 ,  A61B6/032 ,  A61B6/4021 ,  A61B6/4092 ,  A61B6/4291 ,  A61B6/484

摘要： The present invention relates to X-ray image acquisition technology in general. Employing phase-contrast imaging for X-ray image acquisition may significantly enhance the quality and information content of images acquired. However, phase-contrast information may only be obtainable in a small detector region, possibly being too small for a sufficient field of rotation view for specialized X-ray imaging applications. Accordingly, an apparatus for phase-contrast imaging is provided that may allow the acquisition of an enlarged field of view. According to the present invention an apparatus (1) for phase-contrast imaging is provided, comprising an X-ray source (2), an X-ray detector (12) element having a detector size, a beam splitter grating (8) and an analyzer grating (10). An object (6) is arrangeable between the X-ray source (2) and the X-ray detector (12). The beam splitter grating (8) and the analyzer grating (10) are arrangeable between the X-ray source (2) and the X-ray detector (12). X-ray source (2), the beam splitter grating (8), the analyzer grating (10) and the X-ray detector (12) are operatively coupled such that a phase-contrast image of the object (6) is obtainable. The apparatus (1) is adapted for acquiring a phase-contrast image having a field of view larger than the detector size. The X-ray detector element (12) is displaceable and by the displacement of the X-ray detector (12) a phase-contrast image of the field of view is obtainable.

摘要翻译： 本发明一般涉及X射线图像获取技术。 采用X射线图像获取的相位对比成像可显着提高获取图像的质量和信息内容。 然而，相位对比度信息只能在小的检测器区域中获得，对于专门的X射线成像应用，可能对于足够的旋转视场来说太小。 因此，提供了一种用于相位对比成像的装置，其可以允许获取放大的视场。 根据本发明，提供了一种用于相位对比成像的装置（1），包括具有检测器尺寸的X射线源（2），X射线检测器（12）元件，分束器光栅（8）和 分析器光栅（10）。 物体（6）可布置在X射线源（2）和X射线检测器（12）之间。 分束器光栅（8）和分析器光栅（10）可布置在X射线源（2）和X射线检测器（12）之间。 X射线源（2），分束器光栅（8），分析器光栅（10）和X射线检测器（12）可操作地耦合，使得可以获得物体（6）的相位对比度图像。 装置（1）适于获取具有大于检测器尺寸的视场的相位对比度图像。 X射线检测器元件（12）可移动，并且通过X射线检测器（12）的移位，可以获得视场的相位对比图像。

公开(公告)号：US20120250823A1

公开(公告)日：2012-10-04

申请号：US13514166

申请日：2010-12-08

申请人： Gereon Vogtmeier ,  Klaus Juergen Engel ,  Dieter Geller ,  Thomas Koehler ,  Ewald Roessl

发明人： Gereon Vogtmeier ,  Klaus Juergen Engel ,  Dieter Geller ,  Thomas Koehler ,  Ewald Roessl

IPC分类号： A61B6/02

CPC分类号： A61B6/4291 ,  A61B6/4092 ,  A61B6/484 ,  A61B6/583 ,  G21K2207/005

摘要： The present invention relates to an X-ray imaging system and a method for differential phase—contrast imaging of an object. To improve calibration of differential phase—contrast imaging systems and the alignment of the gratings an X-ray imaging system is provided that comprises an X-ray emitting arrangement providing at least partially coherent X-ray radiation and an X-ray detection arrangement comprising a phase-shift diffraction grating, a phase analyzer grating, and an X-ray image detector, all arranged along an optical axis. For stepping, the gratings and/or the X-ray emitting arrangement are provided with at least two actuators arranged opposite to each other with reference to the optical axis. For calibration, calibration projections are acquired without an object, wherein, the emitted X-ray radiation or one of the gratings is stepwise displaced with a calibration displacement value. For examination, measurement projections are acquired with an object, wherein the emitted X-ray radiation or one of the gratings is stepwise displaced with a measurement, a calibration projection is associated to each of the measurement projections by registering the latter with the calibration projections.

摘要翻译： 本发明涉及一种用于物体的差分相位对比成像的X射线成像系统和方法。 为了改进差分相位对比成像系统的校准和光栅的对准，提供了一种X射线成像系统，其包括提供至少部分相干X射线辐射的X射线发射装置和包括 相移衍射光栅，相位分析器光栅和X射线图像检测器，均沿着光轴排列。 对于步进，光栅和/或X射线发射装置设置有相对于光轴彼此相对布置的至少两个致动器。 对于校准，在没有物体的情况下获取校准投影，其中，所发射的X射线辐射或其中一个光栅以校准位移值逐步位移。 为了进行检查，用物体获取测量投影，其中所发射的X射线辐射或其中一个光栅通过测量逐步移位，通过将校准投影与校准投影配准，将校准投影与每个测量投影相关联。

公开(公告)号：US20120099702A1

公开(公告)日：2012-04-26

申请号：US13319527

申请日：2010-06-10

申请人： Klaus Juergen Engel ,  Dieter Geller ,  Gereon Vogtmeier

发明人： Klaus Juergen Engel ,  Dieter Geller ,  Gereon Vogtmeier

IPC分类号： G01N23/04

CPC分类号： A61B6/00 ,  A61B6/4092 ,  A61B6/4291 ,  A61B6/484 ,  G01N23/04 ,  G21K1/06 ,  G21K2207/005

摘要： The present invention generally refers to a correction method for grating-based X-ray differential phase contrast imaging (DPCI) as well as to an apparatus which can advantageously be applied in X-ray radiography and tomography for hard X-ray DPCI of a sample object or an anatomical region of interest to be scanned. More precisely, the proposed invention provides a suitable approach that helps to enhance the image quality of an acquired X-ray image which is affected by phase wrapping, e.g. in the resulting Moiré interference pattern of an emitted X-ray beam in the detector plane of a Talbot-Lau type interferometer after diffracting said X-ray beam at a phase-shifting beam splitter grating. This problem, which is further aggravated by noise in the obtained DPCI images, occurs if the phase between two adjacent pixels in the detected X-ray image varies by more than π radians and is effected by a line integration over the object's local phase gradient, which induces a phase offset error of π radians that leads to prominent line artifacts parallel to the direction of said line integration.

摘要翻译： 本发明总体上涉及一种用于基于光栅的X射线差分相位对比成像（DPCI）的校正方法以及可以有利地应用于X射线照相术和X射线成像的装置，用于样本的硬X射线DPCI 对象或要扫描的感兴趣的解剖区域。 更精确地，所提出的发明提供了一种合适的方法，其有助于增强受到相位包裹影响的获得的X射线图像的图像质量，例如， 在衍射在相移分束器光栅上的所述X射线束之后，在Talbot-Lau型干涉仪的检测器平面中产生的发射的X射线束的莫尔干涉图。 如果所检测的X射线图像中的两个相邻像素之间的相位变化多于＆pgr，则发生由获得的DPCI图像中的噪声进一步恶化的问题。 弧度并且通过对象的局部相位梯度上的线积分实现，其引起相位偏移误差＆pgr; 导致与所述线集成方向平行的突出的线条伪影的弧度。