公开(公告)号：US20170096385A1

公开(公告)日：2017-04-06

申请号：US15154804

申请日：2016-05-13

Applicant: MICROMIDAS, INC.

Inventor： Ryan L. SMITH ,  John BISSELL ,  Makoto N. MASUNO ,  Douglas CANNON ,  Alex B. WOOD

IPC: C07C67/31 ,  C07C67/30

CPC classification number: C07C67/31 ,  C07C1/24 ,  C07C29/095 ,  C07C29/149 ,  C07C51/16 ,  C07C67/03 ,  C07C67/30 ,  C07C2527/167 ,  C07C69/675 ,  C07C69/533 ,  C07C11/167 ,  C07C57/15 ,  C07C69/56 ,  C07C31/207

Abstract: Provided herein are methods that utilize polyhydroxyalkanoates (PHAs) as a substrate for further conversion to C4 and C5 compounds. Polyhydroxyalkanoates can undergo esterification to yield alkyl hydroxyalkanoates and alkyl alkenoates, which may serve as useful precursors in the production of alkadienes and alkenedioic acids, including for example butadiene and butenedioic acid.

公开(公告)号：US20160207897A1

公开(公告)日：2016-07-21

申请号：US15022882

申请日：2014-09-19

Applicant: MICROMIDAS, INC.

Inventor： Alex B. WOOD ,  Makoto N. MASUNO ,  Ryan L. SMITH ,  John BISSEL ,  Dimitri A. HIRSCH-WEIL ,  Robert Joseph ARAIZA ,  Daniel R. HENTON ,  James H. PLONKA

IPC: C07D307/46

CPC classification number: C07D307/46 ,  B01J27/10 ,  C07D307/50

Abstract: The present disclosure provides methods to produce 5-(halomethyl)furfural, including 5-(chloromethyl)furfural, by acid-catalyzed conversion of C6 saccharides, including isomers thereof, polymers thereof, and certain derivatives thereof. The methods make use of acids with lower concentrations, and allows for conversion of sugars into 5-(halomethyl)furfural at higher temperatures and faster reaction or residence times.

Abstract translation: 本公开内容提供了通过C6糖的酸催化转化，包括其异构体，其聚合物及其某些衍生物来生产5-（卤甲基）糠醛的方法，包括5-（氯甲基）糠醛。 该方法利用较低浓度的酸，并允许在更高的温度和更快的反应或停留时间将糖转化为5-（卤甲基）糠醛。

公开(公告)号：US20160002191A1

公开(公告)日：2016-01-07

申请号：US14852306

申请日：2015-09-11

Applicant: MICROMIDAS, INC.

Inventor： Alex B. WOOD ,  Shawn M. BROWNING ,  Makoto N. MASUNO ,  Ryan L. SMITH ,  John BISSELL, II

IPC: C07D307/46

CPC classification number: C07D307/48 ,  C07D307/46

Abstract: The present disclosure provides methods for purifying a 5-(halomethyl)furfural composition, including 5-(chloromethyl)furfural, at operating conditions that decrease or minimize the decomposition or degradation of 5-(chloromethyl)furfural during the process. The methods may employ certain solvents, operating conditions, and/or techniques (e.g., gas stripping). The gaseous 5-(halomethyl)furfural produced from the process can be condensed or deposited to yield 5-(halomethyl)furfural in liquid or solid form. The solid 5-(halomethyl) furfural may be amorphous or crystalline.

Abstract translation: 本公开提供在操作条件下纯化5-（卤代甲基）糠醛组合物的方法，其包括5-（氯甲基）糠醛，其在该过程中减少或最小化5-（氯甲基）糠醛的分解或降解。 这些方法可以使用某些溶剂，操作条件和/或技术（例如，汽提）。 从该方法产生的气态5-（卤代甲基）糠醛可以冷凝或沉积以产生液体或固体形式的5-（卤甲基）糠醛。 固体5-（卤甲基）糠醛可以是无定形或结晶的。

公开(公告)号：US20160002190A1

公开(公告)日：2016-01-07

申请号：US14852152

申请日：2015-09-11

Applicant: MICROMIDAS, INC.

Inventor： Shawn M. BROWNING ,  Makoto N. MASUNO ,  John BISSELL, II ,  Benjamin F. NICHOLSON

IPC: C07D307/46

CPC classification number: C07D307/46 ,  C07D307/18 ,  C07D307/48

Abstract: Provided are solid forms of 5-(halomethyl)furfural, including a crystalline form of 5-(chloromethyl)furfural. Provided are also methods for preparing solid forms of 5-(halomethyl)furfural by crystallization using certain solvents.

Abstract translation: 提供5-（卤代甲基）糠醛的固体形式，包括5-（氯甲基）糠醛的结晶形式。 还提供了使用某些溶剂通过结晶制备5-（卤代甲基）糠醛的固体形式的方法。