-
公开(公告)号：US11998748B2
公开(公告)日：2024-06-04
申请号：US17364609
申请日：2021-06-30
Applicant: MEDTRONIC, INC.
Inventor： Jonathon E. Giftakis , Timothy J. Denison , Paul H. Stypulkowski , Scott R. Stanslaski , Robert S. Raike , Mae Eng , David E. Linde , Thomas Adamski
CPC classification number: A61N1/3614 , A61N1/36142 , A61N1/0531 , A61N1/0534 , A61N2001/083 , A61N1/36082 , A61N1/36185
Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.
-
公开(公告)号：US11529518B2
公开(公告)日：2022-12-20
申请号：US16848595
申请日：2020-04-14
Applicant: Medtronic, Inc.
Abstract: Various embodiments concern delivering electrical stimulation to the brain at a plurality of different levels of a stimulation parameter and sensing a bioelectrical response of the brain to delivery of the electrical stimulation for each of the plurality of different levels of the stimulation parameter. A suppression window of the stimulation parameter can be identified as having a suppression threshold as a lower boundary and an after-discharge threshold as an upper boundary based on the sensed bioelectrical responses. A therapy level of the stimulation parameter can be set for therapy delivery based on the suppression window. The therapy level of the stimulation parameter may be set closer to the suppression threshold than the after-discharge threshold within the suppression window. Data for hippocampal stimulation demonstrating a suppression window is presented.
-
公开(公告)号：US20200306542A1
公开(公告)日：2020-10-01
申请号：US16848595
申请日：2020-04-14
Applicant: Medtronic, Inc.
Abstract: Various embodiments concern delivering electrical stimulation to the brain at a plurality of different levels of a stimulation parameter and sensing a bioelectrical response of the brain to delivery of the electrical stimulation for each of the plurality of different levels of the stimulation parameter. A suppression window of the stimulation parameter can be identified as having a suppression threshold as a lower boundary and an after-discharge threshold as an upper boundary based on the sensed bioelectrical responses. A therapy level of the stimulation parameter can be set for therapy delivery based on the suppression window. The therapy level of the stimulation parameter may be set closer to the suppression threshold than the after-discharge threshold within the suppression window. Data for hippocampal stimulation demonstrating a suppression window is presented.
-
公开(公告)号：US10052485B2
公开(公告)日：2018-08-21
申请号：US14920468
申请日：2015-10-22
Applicant: Medtronic, Inc.
Inventor： Jonathon E. Giftakis , Paul H. Stypulkowski
CPC classification number: A61N1/36139 , A61N1/0534 , A61N1/36082 , A61N1/36096 , A61N1/36171
Abstract: Deep Brain Stimulation (DBS) electrodes are positioned within (or adjacent to) white matter fiber tracts in a brain of patient. The DBS electrodes may be positioned near one or more stimulation sites within the white matter fiber tracts. The stimulation sites may be selected based on the disorder of the patient. In some examples, the stimulation sites may be selected based on one or more symptoms of the patient. In some examples, additional electrodes may be positioned in another area to collect bioelectrical brain signals. The area in which the additional electrodes are placed is an area that is different from the stimulation site but is targeted by stimulation therapy provided at the stimulation site.
-
公开(公告)号：US20170113048A1
公开(公告)日：2017-04-27
申请号：US14920468
申请日：2015-10-22
Applicant: Medtronic, Inc.
Inventor： Jonathon E. Giftakis , Paul H. Stypulkowski
CPC classification number: A61N1/36139 , A61N1/0534 , A61N1/36082 , A61N1/36096 , A61N1/36171
Abstract: Deep Brain Stimulation (DBS) electrodes are positioned within (or adjacent to) white matter fiber tracts in a brain of patient. The DBS electrodes may be positioned near one or more stimulation sites within the white matter fiber tracts. The stimulation sites may be selected based on the disorder of the patient. In some examples, the stimulation sites may be selected based on one or more symptoms of the patient. In some examples, additional electrodes may be positioned in another area to collect bioelectrical brain signals. The area in which the additional electrodes are placed is an area that is different from the stimulation site but is targeted by stimulation therapy provided at the stimulation site.
-
Patent Agency Ranking
16.发明公开公开(公告)号：US20230347152A1
公开(公告)日：2023-11-02
申请号：US18307585
申请日：2023-04-26
Applicant: Medtronic, Inc.
Inventor： Kristin N. Hageman , Scott R. Stanslaski , Erik J. Peterson , Rene A. Molina , Paul H. Stypulkowski , David A. Dinsmoor , Leonid M. Litvak
CPC classification number: A61N1/36139 , A61N1/025
Abstract: A system for closed-loop therapy includes memory configured to store a first set of one or more parameters for a first set of therapeutic electrical stimulation signals. The system includes processing circuitry configured to determine one or more local field potential (LFP) measurements of an LFP that is intrinsically generated, cause stimulation generation circuitry to deliver one or more electrical stimulation signals, determine one or more evoked resonant neural activity (ERNA) signals that are evoked by delivery of respective ones of the electrical stimulation signals, determine a second set of one or more parameters for a second set of therapeutic electrical stimulation signals based on the one or more evoked signals and the one or more LFP measurements, and cause the stimulation generation circuitry to deliver the second set of the one or more therapeutic electrical stimulation signals.
-
公开(公告)号：US20210322770A1
公开(公告)日：2021-10-21
申请号：US17364609
申请日：2021-06-30
Applicant: MEDTRONIC, INC.
Inventor： Jonathon E. Giftakis , Timothy J. Denison , Paul H. Stypulkowski , Scott R. Stanslaski , Robert S. Raike , Mae Eng , David E. Linde , Thomas Adamski
IPC: A61N1/36
Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.
-
公开(公告)号：US20190290912A1
公开(公告)日：2019-09-26
申请号：US15926113
申请日：2018-03-20
Applicant: Medtronic, Inc.
Inventor： Robert S. Raike , Timothy J. Denison , Steven M. Goetz , William J. George , Jonathon E. Giftakis , Lothar Krinke , Gregory F. Molnar , Paul H. Stypulkowski , Scott R. Stanslaski
Abstract: Techniques, systems, and devices are disclosed for delivering stimulation therapy to a patient. In one example, a medical device senses, via one or more electrodes, one or more oscillations of a bioelectrical signal of a brain of a patient. In response to sensing the one or more oscillations, the medical device generates a plurality of bursts of stimulation therapy pulses, the plurality of bursts comprising an inter-burst frequency selected based on a frequency of the one or more oscillations of the bioelectrical signal. Further, the medical device delivers the plurality of bursts of stimulation therapy pulses to the patient to modulate a state of the patient associated with the one or more oscillations of the bioelectrical signal.
-
公开(公告)号：US10252055B2
公开(公告)日：2019-04-09
申请号：US14207926
申请日：2014-03-13
Applicant: Medtronic, Inc.
Inventor： Paul H. Stypulkowski , Jonathon E. Giftakis
Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.
-
公开(公告)号：US20180071530A1
公开(公告)日：2018-03-15
申请号：US15699873
申请日：2017-09-08
Applicant: MEDTRONIC, INC.
Inventor： Jonathon E. Giftakis , Timothy J. Denison , Paul H. Stypulkowski , Scott R. Stanslaski , Robert S. Raike , Mae Eng , David E. Linde , Thomas Adamski
CPC classification number: A61N1/3614 , A61N1/0531 , A61N1/0534 , A61N1/36082 , A61N1/36142 , A61N1/36185 , A61N2001/083
Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.
-
-
-
-
-
-
-
-
-
Search Results
21
records
(took 0.023 seconds)
