公开(公告)号：US4161529A

公开(公告)日：1979-07-17

申请号：US877601

申请日：1978-02-14

申请人： Laszlo Beregi ,  Pierre Hugon ,  Jacques Duhault ,  Michelle Boulanger

发明人： Laszlo Beregi ,  Pierre Hugon ,  Jacques Duhault ,  Michelle Boulanger

IPC分类号： C07D207/08 ,  A61K31/40 ,  A61P3/06 ,  A61P3/08 ,  C07D207/09 ,  C07D207/06

CPC分类号： C07D207/09

摘要： Pyrrolidone derivatives of the formula: ##STR1## wherein R is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl,AndY is hydrogen, saturated or unsaturated hydrocarbon radical up to C.sub.4, hydroxyethyl, hydroxypropyl or carboxymethyl.These compounds are used as medicines especially in the treatment of lipid-metabolism disorders.

摘要翻译： 吡咯烷酮衍生物，其结构式如下：其中R为氢，卤素，低级烷基，低级烷氧基或三氟甲基，Y为氢，饱和或不饱和烃基直至C 4，羟乙基，羟丙基或羧甲基。

公开(公告)号：US4032658A

公开(公告)日：1977-06-28

申请号：US570876

申请日：1975-04-23

申请人： Laszlo Beregi ,  Pierre Hugon ,  Jacques Duhault ,  Michelle Boulanger

发明人： Laszlo Beregi ,  Pierre Hugon ,  Jacques Duhault ,  Michelle Boulanger

IPC分类号： C07D295/08 ,  A61K31/215 ,  A61K31/22 ,  A61P1/00 ,  C07C67/00 ,  C07C227/00 ,  C07C227/14 ,  C07C227/16 ,  C07C227/18 ,  C07C229/14 ,  C07C229/36 ,  C07D209/52 ,  C07D295/088 ,  C07C101/04

CPC分类号： C07D295/088 ,  C07D209/52

摘要： Alkanolamine derivatives and their optical isomers of the formula: ##STR1## wherein: N IS 2 OR 3, ANDR.sub.1 and R.sub.2 are lower alkyl or taken together with the nitrogen to which they are bonded, they form pyrrolidinyl, piperidino, dimethyl piperidino, morpholino, 1-thiomorpholino, azabicyclo [3, 3, 0] octyl or azabicyclo [3, 2, 2] nonyl.These compounds are used as medicines especially in the treatment of obesity, atheroma or metabolic diseases requiring weight reduction and regulation.