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公开(公告)号:US09872900B2
公开(公告)日:2018-01-23
申请号:US15091123
申请日:2016-04-05
Applicant: ModernaTX, Inc.
Inventor: Giuseppe Ciaramella , Axel Bouchon , Eric Yi-Chun Huang
IPC: A61K39/145 , A61K48/00 , A61K39/12 , A61K39/39 , C12N7/00 , A61K31/7105 , A61K9/00 , A61K39/155 , A61K9/127 , A61K9/51 , A61K39/00
CPC classification number: A61K39/145 , A61K9/0019 , A61K9/1271 , A61K9/5123 , A61K9/5146 , A61K31/7105 , A61K39/12 , A61K39/155 , A61K39/39 , A61K48/00 , A61K2039/53 , A61K2039/545 , A61K2039/55555 , C12N7/00 , C12N2760/16122 , C12N2760/16134 , C12N2760/16234
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.