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公开(公告)号：US10806760B2
公开(公告)日：2020-10-20
申请号：US15995393
申请日：2018-06-01
IPC分类号： A61K35/742 , A61P1/14 , C12N1/20 , C12R1/07
摘要： Disclosed are the methods and compositions for the reduction of intestinal gas/flatulence. Specifically a method for reducing flatulence using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856 is disclosed. More specifically, the invention discloses a method for inhibiting the growth of microorganisms that facilitate the production of intestinal gas, using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856.
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公开(公告)号：US10792295B2
公开(公告)日：2020-10-06
申请号：US16001096
申请日：2018-06-06
IPC分类号： A61K31/7024 , A61P31/04 , A61K35/742
摘要： Disclosed are compositions containing at least 10% w/w or above of 1-O-galloyl-β-D-glucose (β-glucogallin) which additionally comprising of about 10% w/w to greater than 60% w/w total mucic acid gallates including mucic acid 1,4-lactone 5-O-gallate, mucic acid 2-O-gallate, mucic acid 6-Methyl ester 2-O-gallate, mucic acid 1-Methyl ester 2-O-gallate and ellagic acid, and a probiotic bacteria Bacillus coagulans MTCC 5856, individually or in combination for inhibiting the growth and managing infections of Helicobacter pylori.
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公开(公告)号：US20190328798A1
公开(公告)日：2019-10-31
申请号：US16396876
申请日：2019-04-29
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
IPC分类号： A61K35/742 , C12N1/20
摘要： The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.
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公开(公告)号：US20190060216A1
公开(公告)日：2019-02-28
申请号：US16117146
申请日：2018-08-30
IPC分类号： A61K8/99 , A61Q19/08 , A61Q17/04 , A61K35/742 , A61P39/06
摘要： Disclosed are the anti-pollution effects of probiotic bacteria Bacillus coagulans MTCC 5856. More specifically the invention discloses the use of probiotic bacteria Bacillus coagulans MTCC 5856 in protecting mammalian skin against the harmful effects of UV and different environmental pollutants. The use of Bacillus coagulans MTCC 5856, as an antioxidant, skin rejuvenating and cleansing agent is also disclosed.
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公开(公告)号：US20180353555A1
公开(公告)日：2018-12-13
申请号：US15995393
申请日：2018-06-01
IPC分类号： A61K35/742 , C12N1/20 , A61P1/14
摘要： Disclosed are the methods and compositions for the reduction of intestinal gas/flatulence. Specifically a method for reducing flatulence using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856 is disclosed. More specifically, the invention discloses a method for inhibiting the growth of microorganisms that facilitate the production of intestinal gas, using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856.
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公开(公告)号：US20180344754A1
公开(公告)日：2018-12-06
申请号：US16001096
申请日：2018-06-06
IPC分类号： A61K31/7024 , A61K35/742 , A61P31/04
摘要： Disclosed are compositions containing at least 10% w/w or above of 1-O-galloyl-β-D-glucose (β-glucogallin) which additionally comprising of about 10% w/w to greater than 60% w/w total mucic acid gallates including mucic acid 1,4-lactone 5-O-gallate, mucic acid 2-O-gallate, mucic acid 6-Methyl ester 2-O-gallate, mucic acid 1-Methyl ester 2-O-gallate and ellagic acid, and a probiotic bacteria Bacillus coagulans MTCC 5856, individually or in combination for inhibiting the growth and managing infections of Helicobacter pylori.
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17.发明授权公开(公告)号：US10966919B2
公开(公告)日：2021-04-06
申请号：US15996791
申请日：2018-06-04
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Lakshmi Mundkur , Shaheen Majeed
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Lakshmi Mundkur , Shaheen Majeed
摘要： Disclosed is the use of partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to prevent skin aging. More specifically the invention discloses the anti-collagenase, anti-elastase, anti-glycation activity and enhancement of TGF-β, epidermal growth factor and hyaluronic acid expression in human dermal fibroblasts, of extracellular metabolites isolated from Bacillus coagulans MTCC 5856.
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公开(公告)号：US20180353553A1
公开(公告)日：2018-12-13
申请号：US15901962
申请日：2018-02-22
IPC分类号： A61K35/742 , A61P1/14 , A61K9/00 , A61K9/48 , A61K9/20 , A23L33/135
CPC分类号： A61K35/742 , A23L33/135 , A23V2002/00 , A61K9/0053 , A61K9/0056 , A61K9/2009 , A61K9/2013 , A61K9/2054 , A61K9/4866 , A61K2035/115 , A61P1/14
摘要： Disclosed is the hypolipidemic potential of Bacillus coagulans. More specifically the invention discloses the cholesterol lowering potential of Bacillus coagulans MTCC 5856 and therapeutic/biological indications thereof.
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19.发明申请公开(公告)号：US20180344781A1
公开(公告)日：2018-12-06
申请号：US15995454
申请日：2018-06-01
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
摘要： Disclosed are hair care compositions containing partially purified extracellular metabolite preparation from strains of Bacillus coagulans. Specifically, the uses of compositions containing extracellular metabolite preparation from a strain of Bacillus coagulans for increasing hair growth, inhibition of 5α-reductase and proliferation of follicle dermal papilla cells and in the management of androgenic alopecia, are disclosed.
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公开(公告)号：US20180339025A1
公开(公告)日：2018-11-29
申请号：US15986854
申请日：2018-05-23
摘要： The present invention discloses compositions containing digestive enzymes for the management and maintenance of metabolic health. Specifically, the invention discloses the use of digestive enzymes comprising α-amylase, lactase, lipase, cellulase and Neutral protease or Acid protease in weight management, reducing cholesterol levels, maintaining healthy gut and improving quality of life.
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