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公开(公告)号：US20180344627A1
公开(公告)日：2018-12-06
申请号：US15996725
申请日：2018-06-04
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
摘要： Disclosed are the skin care applications of a composition containing the partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856. More specifically, the invention discloses the ability of the partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to confer protection to the skin fibroblasts against UV induced cell damage and apoptosis, oxidative stress and inflammation.
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2.发明授权公开(公告)号：US11123382B2
公开(公告)日：2021-09-21
申请号：US15995454
申请日：2018-06-01
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
IPC分类号： A61K35/742 , A61K9/00 , A61P17/08 , A61P17/14 , A61Q7/00 , A61K8/99 , A61K47/32 , A61K47/18 , A61K47/44
摘要： Disclosed are hair care compositions containing partially purified extracellular metabolite preparation from strains of Bacillus coagulans. Specifically, the uses of compositions containing extracellular metabolite preparation from a strain of Bacillus coagulans for increasing hair growth, inhibition of 5α-reductase and proliferation of follicle dermal papilla cells and in the management of androgenic alopecia, are disclosed.
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公开(公告)号：US20190328798A1
公开(公告)日：2019-10-31
申请号：US16396876
申请日：2019-04-29
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
IPC分类号： A61K35/742 , C12N1/20
摘要： The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.
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4.发明授权公开(公告)号：US10966919B2
公开(公告)日：2021-04-06
申请号：US15996791
申请日：2018-06-04
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Lakshmi Mundkur , Shaheen Majeed
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Lakshmi Mundkur , Shaheen Majeed
摘要： Disclosed is the use of partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to prevent skin aging. More specifically the invention discloses the anti-collagenase, anti-elastase, anti-glycation activity and enhancement of TGF-β, epidermal growth factor and hyaluronic acid expression in human dermal fibroblasts, of extracellular metabolites isolated from Bacillus coagulans MTCC 5856.
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5.发明申请公开(公告)号：US20180344781A1
公开(公告)日：2018-12-06
申请号：US15995454
申请日：2018-06-01
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
摘要： Disclosed are hair care compositions containing partially purified extracellular metabolite preparation from strains of Bacillus coagulans. Specifically, the uses of compositions containing extracellular metabolite preparation from a strain of Bacillus coagulans for increasing hair growth, inhibition of 5α-reductase and proliferation of follicle dermal papilla cells and in the management of androgenic alopecia, are disclosed.
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公开(公告)号：US11298381B2
公开(公告)日：2022-04-12
申请号：US16396876
申请日：2019-04-29
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
IPC分类号： A01N63/00 , A61K35/742 , C12N1/20
摘要： The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.
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7.发明申请公开(公告)号：US20180344628A1
公开(公告)日：2018-12-06
申请号：US15996791
申请日：2018-06-04
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Lakshmi Mundkur , Shaheen Majeed
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Lakshmi Mundkur , Shaheen Majeed
摘要： Disclosed is the use of partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to prevent skin aging. More specifically the invention discloses the anti-collagenase, anti-elastase, anti-glycation activity and enhancement of TGF-β, epidermal growth factor and hyaluronic acid expression in human dermal fibroblasts, of extracellular metabolites isolated from Bacillus coagulans MTCC 5856.
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公开(公告)号：US11202810B2
公开(公告)日：2021-12-21
申请号：US16372635
申请日：2019-04-02
IPC分类号： A61K35/742 , A61P1/00 , A61K38/43 , A61K9/48 , A61K9/00
摘要： The present invention discloses a stable probiotic composition comprising Bacillus coagulans individually and/or in combination with multi-enzyme complex for the utilization of lactose and therapeutic management of lactose intolerance. It also discloses a method for the management of lactose intolerance using composition comprising Bacillus coagulans individually and/or in combination with multi-enzyme complex.
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公开(公告)号：US20200316139A1
公开(公告)日：2020-10-08
申请号：US16372635
申请日：2019-04-02
IPC分类号： A61K35/742 , A61P1/00 , A61K9/00 , A61K9/48 , A61K38/43
摘要： The present invention discloses a stable probiotic composition comprising Bacillus coagulans individually and/or in combination with multi-enzyme complex for the utilization of lactose and therapeutic management of lactose intolerance. It also discloses a method for the management of lactose intolerance using composition comprising Bacillus coagulans individually and/or in combination with multi-enzyme complex.
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公开(公告)号：US20190085277A1
公开(公告)日：2019-03-21
申请号：US16136475
申请日：2018-09-20
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Kirankumar Beede
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Kirankumar Beede
IPC分类号： C12C12/00 , A23L33/135 , A61K35/742 , A61K9/00
摘要： A probiotic-alcoholic beverage composition comprising Bacillus coagulans is disclosed herein wherein the said spore or vegetative cell of Bacillus coagulans exhibited high recovery, tolerability, compatibility and viability of spores and vegetative cells after brewing. Methods for brewing an alcoholic beverage composition comprising Bacillus coagulans wherein said spore or bacterium is added during pre-fermentation, during fermentation and post fermentation stages are also disclosed.
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