公开(公告)号：US20240359407A1

公开(公告)日：2024-10-31

申请号：US18643669

申请日：2024-04-23

Applicant: Northwestern University

Inventor： Pengpeng ZHANG ,  Raymond S. FANG ,  Cheng SUN ,  Hao F. ZHANG

IPC: B29C64/386 ,  B29C64/124 ,  B29C64/20 ,  B29D11/00 ,  B29L11/00 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y50/00 ,  B33Y80/00 ,  G02C7/02 ,  G02C7/04

CPC classification number: B29C64/386 ,  B29C64/124 ,  B29C64/20 ,  B29D11/00038 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y50/00 ,  B33Y80/00 ,  G02C7/027 ,  G02C7/04 ,  B29L2011/0041

Abstract: Provided herein are systems and methods for additive manufacture of a customized ocular contact lens for a subject in a fast and convenient manner. In various aspects disclosed herein, methods disclosed herein provide for the imaging of the outer surface of a subject's cornea, designing a customized ocular contact lens based on the data from the imaging of the cornea, including determining anterior and posterior surfaces of the ocular contact lens, manufacturing the ocular contact lens using additive manufacturing, verifying the fit of the customized ocular contact lens on the subject's cornea, and verifying the optical power of the customized ocular contact lens. These features allow for the fast and convenient production of an ocular contact lens customized to a subject's cornea and manufactured to a specified optical power.

公开(公告)号：US20240197963A1

公开(公告)日：2024-06-20

申请号：US18556311

申请日：2022-04-19

Applicant: Northwestern University

Inventor： Yonghui DING ,  Cheng SUN ,  Guillermo AMEER

IPC: A61L27/52 ,  A61L27/26 ,  A61L27/38 ,  A61L27/54 ,  A61N5/06

CPC classification number: A61L27/52 ,  A61L27/26 ,  A61L27/3804 ,  A61L27/54 ,  A61N5/062 ,  A61L2300/414 ,  A61L2300/62 ,  A61L2300/802 ,  A61N2005/0661

Abstract: Provided herein are compositions and methods for 3D bioprinting of mechanically strong and biologically active scaffolds using emulsion bioink for the regeneration of a wide variety of tissues with biochemical functions (e.g., bone, tendon, ligament, cartilage, etc.).

公开(公告)号：US20210396982A1

公开(公告)日：2021-12-23

申请号：US17323302

申请日：2021-05-18

Applicant: Northwestern University

Inventor： Ki-Hee SONG ,  Cheng SUN ,  Hao F. ZHANG

IPC: G02B21/16 ,  G01N21/64 ,  G02B21/36 ,  G02B27/14 ,  G02B5/04

Abstract: A method of microscopy comprises collecting an emission light; symmetrically dispersing the collected emission light into a first order (“1st”) light and a negative first order (“−1st”) light using a grating; wherein the 1st light comprises spectral information and the −1st light comprises spectral information; capturing the 1st light and the −1st light using a camera, localizing the one or more light-emitting materials using localization information determined from both the first spectral image and the second spectral image; and determining spectral information from the one or more light-emitting materials using the first spectral image and/or the second spectral image; wherein the steps of localizing and obtaining are performed simultaneously. A spectrometer for a microscope comprises a dual-wedge prism (“DWP”) for receiving and spectrally dispersing a light beam, wherein the DWP comprises a first dispersive optical device and a second dispersive optical device adhered to each other.