公开(公告)号：US20090054849A1

公开(公告)日：2009-02-26

申请号：US11579546

申请日：2005-05-27

申请人： Rosemary Burnell ,  Tim Barrow-Williams ,  Matthew Brady ,  Nigel Harrison

发明人： Rosemary Burnell ,  Tim Barrow-Williams ,  Matthew Brady ,  Nigel Harrison

IPC分类号： A61M5/32

CPC分类号： A61M5/2033 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/3213 ,  A61M2005/206 ,  A61M2005/3109

摘要： An injection device 110 is described having a housing 112 and a housing closure means 130. The injection device 110 houses a syringe 114 having a needle 118 which is sealed by a boot 120. The housing closure means 130 is arranged so that the boot 120 can be connected to the housing closure means 130 simply, but cannot be removed from the housing closure means 130. The housing 112 and housing closure means 130 are arranged so that upon rotation of the housing closure means 130, the housing closure means 130 is moved axially away from the housing 112 and the boot 120 is removed from the syringe 114. The injection device is simple to use and manufacture.

摘要翻译： 注射装置110被描述为具有壳体112和壳体封闭装置130.注射装置110容纳注射器114，注射器114具有由引导件120密封的针118.壳体封闭装置130被布置成使得护套120可以 只能简单地连接到壳体封闭装置130，但是不能从壳体封闭装置130移除。壳体112和壳体闭合装置130被布置成使得在壳体闭合装置130旋转时，壳体闭合装置130轴向移动 远离壳体112并且引导件120从注射器114移除。注射装置易于使用和制造。

公开(公告)号：US20090012471A1

公开(公告)日：2009-01-08

申请号：US11579564

申请日：2005-05-27

申请人： Nigel Harrison

发明人： Nigel Harrison

IPC分类号： A61M5/20

CPC分类号： A61M5/2033 ,  A61M5/326 ,  A61M2005/206 ,  A61M2005/208 ,  A61M2005/2086

摘要： An injection device 110 is described having a housing 112 that receives a syringe 114 having a needle 118, wherein the syringe is supported in a syringe carrier 150. The syringe 114 and syringe carrier 150 are biased by a return spring 126 from an extended position in which the needle 118 extends from the housing 112 through an exit aperture 128 to a retracted position in which it does not. A drive spring 130 acts via a drive to advance the syringe 114 from its retracted position to its extended position and discharge its contents through the needle 118 and a return spring 126, brought into play when the drive has reached a nominal return position, restores the syringe 114 to its retracted position. The injection device is less prone to failure than prior art devices and is safer should failure occur.

摘要翻译： 注射装置110被描述为具有容纳具有针118的注射器114的壳体112，其中注射器被支撑在注射器载体150中。注射器114和注射器载体150由复位弹簧126从延伸位置偏置 针118从壳体112通过出口孔128延伸到缩回位置。 驱动弹簧130通过驱动器作用，以将注射器114从其缩回位置推进到其延伸位置，并且通过针头118将其内容物排出，并且当驱动器达到标称返回位置时使复原弹簧126起作用，恢复弹簧 注射器114到其缩回位置。 注射装置比现有技术的装置不容易发生故障，并且更安全地应当发生故障。

公开(公告)号：US20050273055A1

公开(公告)日：2005-12-08

申请号：US11150788

申请日：2005-06-10

申请人： Nigel Harrison ,  Matthew Brady ,  Gregory Berman ,  David Johnston ,  Rosemary Habeshaw

发明人： Nigel Harrison ,  Matthew Brady ,  Gregory Berman ,  David Johnston ,  Rosemary Habeshaw

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/32

CPC分类号： A61M5/326 ,  A61M5/2033 ,  A61M2005/206 ,  A61M2005/3143 ,  A61M2005/31516

摘要： An injection device including a housing for containing a syringe having a bore extending from an end surface, a needle communicating with the bore through the end surface and a dispensing piston movable in said bore towards said end surface so as to expel the contents of the syringe through the needle, the housing having an opening at one end through which the needle may extend, a resilient member for biassing the syringe and the needle inwardly off the housing, a first coupling element moveable towards said one end so as to move the needle of the syringe out of the opening and to move the dispensing piston of the syringe towards the end surface, a mechanism operable to release the syringe such that the needle moves inwardly off the housing, a drive coupling for extending from said first coupling element to the dispensing piston of the syringe so as to transfer movement of said first coupling element to the dispensing piston wherein the mechanism is triggered to release the syringe and includes components to delay release of the syringe until a predetermined period after being triggered such that it can be ensured that the dispensing piston reaches the end surface before the syringe is released and/or the mechanism includes an inertial mass moveable with the first coupling element and drive coupling and a release member actuable by the inertial mass to release the syringe such that when the dispensing piston releases the end surface of the syringe and the first coupling element and drive coupling stop moving, the inertial mass continues to move so as to actuate the release member to release the syringe.

摘要翻译： 一种注射装置，包括用于容纳具有从端表面延伸的孔的注射器的壳体，通过端表面与孔连通的针以及可在所述孔中朝向所述端表面移动的分配活塞，以便排出注射器的内容物 通过所述针，所述壳体在所述针可以延伸穿过的一端具有开口，用于将所述注射器和所述针向内偏离所述壳体的弹性构件，朝向所述一端可移动的第一联接元件， 所述注射器离开所述开口并且使所述注射器的分配活塞朝向所述端表面移动，所述机构可操作以释放所述注射器，使得所述针向内移出所述壳体;驱动联接器，用于从所述第一联接元件延伸到所述分配 以便将所述第一联接元件的运动传递到所述分配活塞，其中所述机构被触发以释放所述注射器 包括用于延迟注射器释放直到在被触发之后的预定时间段的释放的部件，使得可以确保在注射器被释放之前分配活塞到达端表面，和/或该机构包括可与第一联接元件一起移动的惯性块，以及 驱动联接器和由惯性块致动的释放构件以释放注射器，使得当分配活塞释放注射器的端面并且第一联接元件和驱动联接件停止移动时，惯性质量块继续移动，以便致动 释放构件释放注射器。

公开(公告)号：US09675757B2

公开(公告)日：2017-06-13

申请号：US11579360

申请日：2005-05-27

申请人： Nigel Harrison

发明人： Nigel Harrison

IPC分类号： A61M5/20 ,  A61M5/32 ,  A61M5/24

CPC分类号： A61M5/2033 ,  A61M5/24 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/202 ,  A61M2005/206 ,  A61M2005/3261

摘要： An injection device (210) is described. A housing (212) receives a syringe and includes a return spring (226) for biasing the syringe from an extended position in which its needle (218) extends from the housing (212) to a retracted position in which the it does not. A drive spring (230) acts on a first drive element (232) and a second drive element (234) acts upon the syringe to advance it from its retracted position to its extended position and discharge its contents through the needle. The first drive element (232) is capable of movement relative to the second (234) once a nominal decoupling position has been reached. A release mechanism is activated when the first drive element (234) is further advanced to a nominal release position, to release the syringe (214) from the action of the drive spring (230), whereupon the return spring (226) restores the syringe (214) to its retracted position. Decoupling of the drive elements is achieved with a particular form of releasable drive coupling using two pairs of overlying flexible arms (235, 247). A particular form of release mechanism that also uses flexible arms (233) is also envisaged.

公开(公告)号：US20110005167A1

公开(公告)日：2011-01-13

申请号：US12446593

申请日：2007-10-17

申请人： Gunther Victor Maria Emiel Van Goolen ,  Stefaan Jaak Vanquickenborne ,  Nigel Harrison

发明人： Gunther Victor Maria Emiel Van Goolen ,  Stefaan Jaak Vanquickenborne ,  Nigel Harrison

IPC分类号： B65B1/00 ,  A61J3/07 ,  B65G47/00 ,  B65G37/00

CPC分类号： A61J3/07 ,  A61J3/072 ,  A61J3/074 ,  B65G35/08

摘要： The present invention relates to a transfer line for the transfer of identical filled two-piece capsules between two successive processing stations comprising a and on unloading area, a plurality of identical transfer units each comprising a plurality of cavities each adapted to receive a capsule at the loading area and to let such capsule being unloaded at the unloading area, said plurality of cavities of each transfer unit being designed so as to receive in a first relative configuration the groups of filled two-piece capsules when located at a loading position in the loading area and so as to discharge these groups when located at an unloading position in the unloading area, a conveyor device adapted to temporarily and individually support the transfer units so as to transfer them from the loading position to the unloading position and vice-versa, while keeping them substantially in a same orientation in the loading and unloading positions, and at least from the loading position to the unloading position.

摘要翻译： 本发明涉及一种用于在两个连续的处理站之间传送相同的填充的两件式胶囊的传送管线，包括装载区域和卸载区域，多个相同的传送单元，每个传送单元包括多个腔室，每个腔体适于容纳胶囊 在所述装载区域处，并且使所述胶囊在所述卸载区域被卸载，所述每个传送单元的所述多个空腔被设计成在第一相对构型中接收所述填充的两件式胶囊组，当位于所述装载位置 装载区域，并且当位于卸载区域中的卸载位置时排出这些组;传送装置，适于临时和单独地支撑传送单元，以便将它们从装载位置传送到卸载位置，反之亦然 同时保持它们在装载和卸载位置上基本保持相同的方向，并且至少从装载 位置到卸载位置。

公开(公告)号：US20080312606A1

公开(公告)日：2008-12-18

申请号：US11579359

申请日：2005-05-27

申请人： Nigel Harrison ,  Rosemary Habeshaw

发明人： Nigel Harrison ,  Rosemary Habeshaw

IPC分类号： A61M5/315

CPC分类号： A61M5/2033 ,  A61M5/31511 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/326

摘要： An injection device is described. A syringe 114 is received within a housing, the syringe having a bore terminating at a forward end in a hypodermic needle 118 and at a rearward end in a flared opening 210 in which a bung 134a having a bore 206 surrounded by a skirt 208 is inserted. A drive element 134 has a forward end consisting of a substantially flat annular region 200 that bears upon the skirt 208 of the bung 134a and surrounds a conical middle region 202 that is received in the bore 206 of the bung 134a. An actuator advances the drive element 134 so as to advance the bung 134a and discharge the contents of the syringe through the needle 118. The opening 210 in the rear of the glass syringe is flared by being provided with a radius. The combination of the radius at the opening 210 and the projecting conical middle region 202 of the drive element allows misalignments of the two to be managed during automated assembly. This is because the conical middle region 202 either pass straight into the opening 210 of the syringe, or contact the radius, which guides them towards the centre of the syringe bore. The radius and the substantially flat annular region 200 and the central conical portion 202 of the drive element 134 are so shaped and dimensioned that axial misalignment between the syringe 114 and the drive element 134 during assembly of the injection device are corrected by, firstly, the conical middle region 202 of the drive element 134 riding up the radius to a point at which, secondly, the substantially flat annular region 200 also makes contact with and rides up the radius, to align the drive element 134 in the bore of the syringe 114.

摘要翻译： 描述注射装置。 注射器114被容纳在壳体内，注射器具有终止于皮下注射针118中的前端的孔，并且在扩张开口210中的后端处插入具有由裙部208包围的孔206的栓134a插入 。 驱动元件134具有由基本上平坦的环形区域200组成的前端，该基部平坦的环形区域200承载在塞子134a的裙部208上并且包围容纳在塞子134a的孔206中的锥形中间区域202。 致动器使驱动元件134前进，以便推动塞舌134a并通过针头118排出注射器的内容物。通过设置半径来使玻璃注射器后部的开口210展开。 开口210处的半径和驱动元件的突出的锥形中间区域202的组合允许在自动组装期间管理的两者的对准。 这是因为锥形中间区域202或者直接进入注射器的开口210，或者接触半径，其将它们引导到注射器孔的中心。 驱动元件134的半径和基本平坦的环形区域200和中心圆锥形部分202的形状和尺寸使得在注射装置的组装过程中注射器114和驱动元件134之间的轴向未对准被首先校正 驱动元件134的圆锥形中间区域202沿着半径加载到其中，其中基本上平坦的环形区域200也与半径接触并且向上跨过半径，以将驱动元件134对准注射器114的孔中 。

公开(公告)号：US20080312591A1

公开(公告)日：2008-12-18

申请号：US11579360

申请日：2005-05-27

申请人： Nigel Harrison

发明人： Nigel Harrison

IPC分类号： A61M5/20

CPC分类号： A61M5/2033 ,  A61M5/24 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/202 ,  A61M2005/206 ,  A61M2005/3261

摘要： An injection device (210) is described. A housing (212) receives a syringe and includes a return spring (226) for biasing the syringe from an extended position in which its needle (218) extends from the housing (212) to a retracted position in which the it does not. A drive spring (230) acts on a first drive element (232) and a second drive element (234) acts upon the syringe to advance it from its retracted position to its extended position and discharge its contents through the needle. The first drive element (232) is capable of movement relative to the second (234) once a nominal decoupling position has been reached. A release mechanism is activated when the first drive element (234) is further advanced to a nominal release position, to release the syringe (214) from the action of the drive spring (230), whereupon the return spring (226) restores the syringe (214) to its retracted position. Decoupling of the drive elements is achieved with a particular form of releasable drive coupling using two pairs of overlying flexible arms (235, 247). A particular form of release mechanism that also uses flexible arms (233) is also envisaged.

摘要翻译： 描述注射装置（210）。 一个外壳（212）接收一个注射器并且包括一个复位弹簧（226），用于将注射器从伸出位置偏压，在该延伸位置，其针（218）从壳体（212）延伸到缩回位置。 驱动弹簧（230）作用在第一驱动元件（232）上，第二驱动元件（234）作用在注射器上，以将其从其缩回位置推进到其延伸位置，并通过针将其内容物排出。 一旦达到标称解耦位置，第一驱动元件（232）能够相对于第二驱动元件（234）运动。 当第一驱动元件（234）进一步前进到标称释放位置时，释放机构被激活，以从驱动弹簧（230）的作用释放注射器（214），于是复位弹簧（226）恢复注射器 （214）到其缩回位置。 通过使用两对上覆的柔性臂（235,247）的特定形式的可释放的驱动联接来实现驱动元件的去耦。 还设想了也使用柔性臂（233）的特定形式的释放机构。

公开(公告)号：US07093594B2

公开(公告)日：2006-08-22

申请号：US10398066

申请日：2001-09-24

申请人： Nigel Harrison ,  Daniel Godfrey

发明人： Nigel Harrison ,  Daniel Godfrey

IPC分类号： A61M15/00

CPC分类号： F15C3/04 ,  A61M15/0076 ,  A61M15/009 ,  A61M15/0091 ,  A61M15/0096 ,  B29C45/14336 ,  B29L2031/755

摘要： A dosing device comprising a dispenser (26) for dispensing a dose material and a dose actuation mechanism (44) is provided. The dose actuation mechanism (44) comprises a number of integrally hinged links (52, 54, 55) which are connected to each other at hinging points. A deflectable tongue (157), moveable in response to air flow from inhalation by a patient is attached to a first link (52), to move the first link in response to air flow, movement of the first link being transferred to a second link (54) to cause actuation of the dispenser. The first link rests at an over center, or stable, position prior to operation, and moves under center during operation of the device to trigger movement of the second link. The dose actuation mechanism is a one-piece moulding from plastics material.

摘要翻译： 提供了一种包括用于分配剂量材料的分配器（26）和剂量致动机构（44）的计量装置。 剂量致动机构（44）包括在铰接点处彼此连接的多个整体铰接的连杆（52,54,55）。 响应于患者吸入的空气流动而移动的可偏转舌片157附接到第一连杆52，以响应于空气流动移动第一连杆，第一连杆的运动被传递到第二连杆 （54）以引起分配器的致动。 第一连杆在操作之前处于过中心或稳定的位置，并且在设备的操作期间在中心下移动以触发第二连杆的移动。 剂量致动机构是从塑料材料一体成型。