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29 条记录 (耗时 0.066 秒)

    Method for enhancing mutant enzyme activities in Gaucher disease
    11.
    发明授权
    Method for enhancing mutant enzyme activities in Gaucher disease 有权
    增强戈谢病突变酶活性的方法

    公开(公告)号：US07141582B2

    公开(公告)日：2006-11-28

    申请号：US10989258

    申请日：2004-11-16

    申请人： Jian-Qiang Fan ,  Satoshi Ishii ,  Naoki Asano

    发明人： Jian-Qiang Fan ,  Satoshi Ishii ,  Naoki Asano

    IPC分类号： A61K31/445 ,  A61K31/70 ,  A61K31/435

    CPC分类号： A61K31/445 ,  A61K31/70 ,  A61K31/7008 ,  C07D451/06 ,  C12N9/2465

    摘要： Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method are imino sugars and related compounds. In particular, C8–12-alkyl derivatives of N-alkyl-deoxynojirimycin, isofagomine compounds, and calystegine compounds are effective to enhance glucocerebrosidase activity.

    摘要翻译： 通过以有效增加酶的活性的量施用葡糖脑苷脂酶的竞争性抑制剂，在哺乳动物细胞中增强与戈谢病相关的酶的活性的方法。 用于该方法的优选化合物是亚氨基糖和相关化合物。 特别地，N-烷基脱氧野尻霉素的C8-12-烷基衍生物，异佛胺化合物和钙半胱氨酸化合物对增强葡糖脑苷脂酶活性是有效的。

    Injection mold design system and injection mold design method
    14.
    发明授权
    Injection mold design system and injection mold design method 失效
    注塑模具设计系统和注塑模具设计方法

    公开(公告)号：US06192327B1

    公开(公告)日：2001-02-20

    申请号：US09084965

    申请日：1998-05-27

    申请人： Shusaku Nishiyama ,  Shingo Yamaguchi ,  Tatsuo Kimura ,  Masayuki Imakado ,  Naoki Asano ,  Fumihiko Makiuchi

    发明人： Shusaku Nishiyama ,  Shingo Yamaguchi ,  Tatsuo Kimura ,  Masayuki Imakado ,  Naoki Asano ,  Fumihiko Makiuchi

    IPC分类号： G06F10100

    CPC分类号： B29C33/3835 ,  B29C45/26 ,  G05B19/4099 ,  G05B2219/35044 ,  G05B2219/35078 ,  Y02P90/265

    摘要： An injection mold design method for correcting a profile of a product to be fabricated into a releasable profile from a mold to design an injection mold based on a corrected product shape, utilizing a storage device for storing information of the product shape and mold profile, a display device for displaying the product shape or the mold profile on a screen based on the information read from the storage device, an input device for inputting designation information necessary for correction of the product shape or the mold profile, and a controlling device for unloading information of lines or planes being obstructive to correction of the product shape and the mold profile in the storage device in response to the designation information input by the input device. The method comprises removing lines or planes from the screen, and replotting the lines or the planes on the screen in terms of the information of lines or planes unloaded into the storage device after the correction operation of the product shape or the mold profile is completed.

    摘要翻译： 一种注射模具设计方法，用于基于校正的产品形状来校正要从模具制造成可释放轮廓的产品的轮廓的轮廓，利用用于存储产品形状和模具轮廓的信息的存储装置， 显示装置，用于基于从存储装置读取的信息在屏幕上显示产品形状或模具轮廓;输入装置，用于输入用于校正产品形状或模具轮廓所需的指定信息;以及控制装置，用于卸载信息 线或平面响应于由输入装置输入的指定信息而阻碍了存储装置中的产品形状和模具轮廓的校正。 该方法包括从屏幕上移除线或平面，并且在产品形状或模具轮廓的校正操作完成之后，根据卸载到存储装置中的线或平面的信息将屏幕上的线或平面重新划线。

    Sheet feeding apparatus
    15.
    发明授权
    Sheet feeding apparatus 失效
    送纸装置

    公开(公告)号：US5292116A

    公开(公告)日：1994-03-08

    申请号：US871549

    申请日：1992-04-21

    申请人： Ryukichi Inoue ,  Yutaka Kikuchi ,  Yasuyoshi Hayakawa ,  Naoki Asano ,  Kazuhiro Nomoto

    发明人： Ryukichi Inoue ,  Yutaka Kikuchi ,  Yasuyoshi Hayakawa ,  Naoki Asano ,  Kazuhiro Nomoto

    IPC分类号： B65H1/26 ,  B65H1/04 ,  B65H3/54 ,  G03G15/00

    CPC分类号： B65H1/266 ,  B65H1/04 ,  B65H2301/331

    摘要： The present invention provides a sheet feeding apparatus having a sheet supporting tray removably mountable within the sheet feeding apparatus and adapted to stack and support sheets, a regulating device provided on the sheet supporting tray and adapted to regulate and position lateral edges of the sheets stacked in the sheet supporting tray, an urging mechanism for urging with a predetermined urging force the sheets stacked in the sheet supporting tray against the regulating device, and an urging force adjusting mechanism for adjusting the urging mechanism so that the urging mechanism can urge the sheets against the regulating device with greater force during insertion of the sheet supporting tray into the sheet feeding apparatus.

    摘要翻译： 本发明提供了一种片材进给装置，其具有可拆卸地安装在片材进给装置内并适于堆叠和支撑片材的片材支撑盘托，设置在片材支撑托盘上的调节装置，并且适于调节和定位堆叠在片材进给装置中的片材的侧边缘 片材支撑托盘，用于以预定的推动力推压堆叠在片材支撑托盘中的片材抵靠调节装置的推动机构，以及用于调节推动机构的推动力调节机构，使得推动机构可以将片材推压 在将片材支承托盘插入片材进给装置中时具有更大的力的调节装置。

    MASKING PASTE, METHOD OF MANUFACTURING SAME, AND METHOD OF MANUFACTURING SOLAR CELL USING MASKING PASTE
    16.
    发明申请
    MASKING PASTE, METHOD OF MANUFACTURING SAME, AND METHOD OF MANUFACTURING SOLAR CELL USING MASKING PASTE 有权
    掩模膏，其制造方法和使用掩模膏制造太阳能电池的方法

    公开(公告)号：US20090142911A1

    公开(公告)日：2009-06-04

    申请号：US12063542

    申请日：2006-08-08

    申请人： Naoki Asano ,  Yasushi Funakoshi

    发明人： Naoki Asano ,  Yasushi Funakoshi

    IPC分类号： H01L21/22

    CPC分类号： H01L31/06 ,  H01L21/32 ,  H01L31/03529 ,  Y02E10/50

    摘要： A masking paste used as a mask for controlling diffusion when diffusing a p-type dopant and an n-type dopant into a semiconductor substrate and forming a high-concentration p-doped region and a high concentration n-doped region is provided that contains at least a solvent, a thickening agent, and SiO2 precursor and/or a TiO2 precursor, Further, a manufacturing method of a solar cell is provided in which the masking paste is pattern-formed on the semiconductor substrate and then the p-type dopant and the n-type dopant are diffused.

    摘要翻译： 在将p型掺杂剂和n型掺杂剂扩散到半导体衬底中并形成高浓度p掺杂区域和高浓度n掺杂区域时，用作掩模以用于控制扩散的掩模糊剂包含在 至少一种溶剂，增稠剂，和SiO 2前体和/或TiO 2前体。此外，提供一种太阳能电池的制造方法，其中掩模膏在图案形成在半导体衬底上，然后是p型掺杂剂和 n型掺杂剂被扩散。

    Injection mold design system and injection mold design method
    18.
    发明授权
    Injection mold design system and injection mold design method 失效
    注塑模具设计系统和注塑模具设计方法

    公开(公告)号：US06618643B2

    公开(公告)日：2003-09-09

    申请号：US09965865

    申请日：2001-10-01

    申请人： Shusaku Nishiyama ,  Shingo Yamaguchi ,  Tatsuo Kimura ,  Masayuki Imakado ,  Naoki Asano ,  Fumihiko Makiuchi

    发明人： Shusaku Nishiyama ,  Shingo Yamaguchi ,  Tatsuo Kimura ,  Masayuki Imakado ,  Naoki Asano ,  Fumihiko Makiuchi

    IPC分类号： G06F760

    CPC分类号： B29C33/3835 ,  B29C45/26 ,  G05B19/4099 ,  G05B2219/35044 ,  G05B2219/35078 ,  Y02P90/265

    摘要： An injection mold design method for correcting a profile of a product to be fabricated into a releasable profile from a mold to design an injection mold based on a corrected product shape, utilizing a storage device for storing information of the product shape and mold profile, a display device for displaying the product shape or the mold profile on a screen based on the information read from the storage device, an input device for inputting designation information necessary for correction of the product shape or the mold profile, and a controlling device for unloading information of lines or planes being obstructive to correction of the product shape and the mold profile in the storage device in response to the designation information input by the input device. The method comprises removing lines or planes from the screen, and replotting the lines or the planes on the screen in terms of the information of lines or planes unloaded into the storage device after the correction operation of the product shape of the mold profile is completed.

    摘要翻译： 一种注射模具设计方法，用于基于校正的产品形状来校正要从模具制造成可释放轮廓的产品的轮廓的轮廓，利用用于存储产品形状和模具轮廓的信息的存储装置， 显示装置，用于基于从存储装置读取的信息在屏幕上显示产品形状或模具轮廓;输入装置，用于输入用于校正产品形状或模具轮廓所需的指定信息;以及控制装置，用于卸载信息 线或平面响应于由输入装置输入的指定信息而阻碍了存储装置中的产品形状和模具轮廓的校正。 该方法包括：从模具轮廓的产品形状的校正操作完成之后，从屏幕上移除线或平面，以及将屏幕上的线或平面重新划分为在卸载到存储装置中的线或平面的信息。

    Milling machine and methods of milling and menu selection
    20.
    发明授权
    Milling machine and methods of milling and menu selection 失效
    铣床和铣削和菜单选择方法

    公开(公告)号：US6065858A

    公开(公告)日：2000-05-23

    申请号：US735741

    申请日：1996-10-23

    申请人： Shingo Yamaguchi ,  Tatsuo Kimura ,  Masayuki Imakado ,  Naoki Asano

    发明人： Shingo Yamaguchi ,  Tatsuo Kimura ,  Masayuki Imakado ,  Naoki Asano

    IPC分类号： G05B19/19 ,  G06F19/00 ,  G06G7/66

    CPC分类号： G05B19/19 ,  G05B2219/36121 ,  G05B2219/36321 ,  G05B2219/45145 ,  G05B2219/50357 ,  Y02P90/265

    摘要： Determining the intersection line of a plane Z=Z1 perpendicular to the axial direction of an end mill and a design surface, determining equal pitch offset-curves as path elements inside a material and outside the intersection line, determining intersection points crossing a material boundary from outside to inside as cutting start and end points and reverse respectively when going along the path, determining a tangent to the path element at the cutting start point and determining the intersection point of the tangent and a material boundary offset line outside the materials as the end mill approach start point. Determining a point at a minimum height on a design surface and determining such a ball end mill that a mill model does not interfere with the design surface when aligning the tip of the mill model with the point. When performing offset milling by a thickness .delta., making a mill model by reducing the outline of a rotating end mill by the thickness .delta., placing the model on the design surface to determine a path and actually cutting with the end mill along the path. Displaying a tree-type hierarchical menu and selecting one item of the lowest layer in the menu, resulting in selecting all related items in the hierarchical layers above it automatically.

    摘要翻译： 确定垂直于立铣刀和设计表面的轴向的平面Z = Z1的交线，确定作为材料内部和交叉线外部的路径元素的相等间距偏移曲线，确定穿过物料边界的交叉点 在沿着路径行进时，分别作为切割开始点和终点并反转，确定切割开始点处的路径元素的切线，并确定材料外部的切线和材料边界偏移线的交点为终点 磨机起点。 确定设计表面上最小高度的点，并确定这样的球头铣刀，当铣刀模型的尖端与点对准时，轧机模型不干扰设计表面。 当通过厚度δ进行偏移铣削时，通过将旋转端铣刀的轮廓减小厚度δ来制造轧机模型，将模型放置在设计表面上以确定路径并且实际上沿端铣刀切割。 显示树型分层菜单并选择菜单中最下层的一个项目，从而自动选择上层层次结构中的所有相关项目。