公开(公告)号：US20060118072A1

公开(公告)日：2006-06-08

申请号：US11303044

申请日：2005-12-15

申请人： Jens Meintschel ,  Petra Schulz

发明人： Jens Meintschel ,  Petra Schulz

IPC分类号： F01L1/34

CPC分类号： F01L1/34 ,  F01L1/3442 ,  F01L1/46 ,  F01L2001/34426 ,  F01L2001/3443

摘要： In a camshaft adjuster including a camshaft driven by a crankshaft of an internal combustion engine via an adjustable drive mounted on the camshaft by a mounting screw having a hollow shank with an axially movable control piston disposed in the hollow shank and an electromagnetic device for operating the control piston, the control piston is axially movable by the electromagnetic device for controlling the supply of oil to, and its release from, the camshaft adjuster for controlling the relative angular position of the crankshaft and the camshaft, the electromagnetic device operated piston also forming an oil pump for providing a supply of oil to the camshaft adjuster.

摘要翻译： 在凸轮轴调节器中，包括由内燃机的曲轴驱动的凸轮轴，所述凸轮轴由安装在所述凸轮轴上的可调节驱动装置通过具有中空杆的安装螺钉，所述中空杆具有设置在所述中空杆中的可轴向移动的控制活塞，以及电磁装置， 控制活塞可通过电磁装置轴向移动，用于控制向凸轮轴调节器供油并释放以控制曲轴和凸轮轴的相对角位置，电磁装置操作的活塞也形成 用于向凸轮轴调节器供油的油泵。

公开(公告)号：US08809510B2

公开(公告)日：2014-08-19

申请号：US13879283

申请日：2011-10-13

申请人： Hubert Brandstaetter ,  Petra Schulz ,  Juergen Roemisch

发明人： Hubert Brandstaetter ,  Petra Schulz ,  Juergen Roemisch

IPC分类号： C07K1/18 ,  A61K38/00 ,  G01N30/02 ,  C07K1/22 ,  C07K1/36 ,  A61K39/00 ,  C07K14/705 ,  A61K35/16 ,  C07K14/47

CPC分类号： C07K14/472 ,  A61K38/1709 ,  C07K1/36 ,  C07K14/435 ,  C07K14/47

摘要： A method for purification of complement Factor H from a complement Factor H containing source such as blood or blood plasma, in particular a caprylate precipitate of a Factor H containing source, which is e.g. obtained by addition of caprylate ions to fractions of blood or plasma, comprising the steps of: a) providing a Factor H containing source, in particular reconstitution of caprylate precipitate to provide a complement Factor H containing solution; b) performing a cation exchange chromatography in particular as first chromatographic step; c) performing an anion exchange chromatography; d) performing a hydroxyl apatite chromatography; e) followed by ultra/diafiltration to obtain a complement Factor H concentrate.

摘要翻译： 用于从补体因子H纯化补体因子H的方法，所述补体因子H含有血液或血浆中的源，特别是含H因子的来源的辛酸盐沉淀物。 通过向血液或血浆的级分中加入辛酸盐离子获得，包括以下步骤：a）提供含有因子H的来源，特别是辛酸沉淀重构以提供补体因子H的溶液; b）特别是进行阳离子交换层析作为第一色谱步骤; c）进行阴离子交换层析; d）进行羟基磷灰石层析; e），然后进行超/渗滤以获得补体因子H浓缩物。

公开(公告)号：US20130203971A1

公开(公告)日：2013-08-08

申请号：US13879283

申请日：2011-10-13

申请人： Hubert Brandstaetter ,  Petra Schulz ,  Juergen Roemisch

发明人： Hubert Brandstaetter ,  Petra Schulz ,  Juergen Roemisch

IPC分类号： C07K1/36 ,  C07K14/435

CPC分类号： C07K14/472 ,  A61K38/1709 ,  C07K1/36 ,  C07K14/435 ,  C07K14/47

摘要： A method for purification of complement Factor H from a complement Factor H containing source such as blood or blood plasma, in particular a caprylate precipitate of a Factor H containing source, which is e.g. obtained by addition of caprylate ions to fractions of blood or plasma, comprising the steps of: a) providing a Factor H containing source, in particular reconstitution of caprylate precipitate to provide a complement Factor H containing solution; b) performing a cation exchange chromatography in particular as first chromatographic step; c) performing an anion exchange chromatography; d) performing a hydroxyl apatite chromatography; e) followed by ultra/diafiltration to obtain a complement Factor H concentrate.