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公开(公告)号：US11858986B2
公开(公告)日：2024-01-02
申请号：US17092998
申请日：2020-11-09
Applicant: PFIZER INC. , THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
Inventor： Stefano V. Gulla , Christine Huard , Janet Elizabeth Buhlmann , Juan Carlos Almagro , Sreekumar R. Kodangattil , Steven A. Greenberg , Edward Roland Lavallie , Eric M. Bennett , Lidia Mosyak , James Perry Hall , Anthony John Coyle
CPC classification number: C07K16/249 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The invention relates to antibodies, or antigen-binding fragments thereof, that specifically binds to interferon beta (IFNβ). Such antibodies, or antigen-binding fragments thereof, are are useful for various therapeutic or diagnostic purposes.
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公开(公告)号：US10647756B2
公开(公告)日：2020-05-12
申请号：US15155324
申请日：2016-05-16
Applicant: Pfizer Inc.
Abstract: Disclosed herein are humanized antibodies in which human germline residues are introduces to the complementarity determining regions (CDRs) of a non-human donor antibody. Also described herein are libraries of antibody variable domains (e.g., phage-display libraries) and methods for screening for humanized antibodies.
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公开(公告)号：US20170313769A1
公开(公告)日：2017-11-02
申请号：US15581079
申请日：2017-04-28
Applicant: PFIZER INC. , THE BRIGHAM AND WOMEN?S HOSPITAL, INC.
Inventor： Stefano V. Gulla , Christine Huard , Janet Elizabeth Buhlmann , Juan Carlos Almagro , Sreekumar R. Kodangattil , Steven A. Greenberg , Edward Roland Lavallie , Eric M. Bennett , Lidia Mosyak , James Perry Hall , Anthony John Coyle
IPC: C07K16/24
Abstract: The invention relates to antibodies, or antigen-binding fragments thereof, that specifically binds to interferon beta (IFNβ). Such antibodies, or antigen-binding fragments thereof, are useful for various therapeutic or diagnostic purposes.
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