公开(公告)号：US20170298447A1

公开(公告)日：2017-10-19

申请号：US15586747

申请日：2017-05-04

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12Q1/68 ,  A61K38/00 ,  C12N15/11 ,  C12N15/113

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US09650680B2

公开(公告)日：2017-05-16

申请号：US14999879

申请日：2016-07-13

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12N15/11 ,  C07H21/04 ,  C12Q1/68 ,  A61K38/00 ,  C12N15/113

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US09650679B2

公开(公告)日：2017-05-16

申请号：US14756185

申请日：2015-08-13

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C07H21/04 ,  C12N15/11 ,  C12Q1/68 ,  A61K38/00 ,  C12N15/113

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US20160319363A1

公开(公告)日：2016-11-03

申请号：US14999879

申请日：2016-07-13

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12Q1/68

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

Abstract translation: 本文描述了与前列腺和肺癌相关的新型多核苷酸。 多核苷酸是miRNA和miRNA前体。 公开了可用于诊断，预后和治疗这些医疗条件的相关方法和组合物。 本文还描述了可用于鉴定前列腺和肺癌调节剂的方法。

公开(公告)号：US20160046935A1

公开(公告)日：2016-02-18

申请号：US14756185

申请日：2015-08-13

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12N15/113 ,  C12Q1/68

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

Abstract translation: 本文描述了与前列腺和肺癌相关的新型多核苷酸。 多核苷酸是miRNA和miRNA前体。 公开了可用于诊断，预后和治疗这些医疗条件的相关方法和组合物。 本文还描述了可用于鉴定前列腺和肺癌调节剂的方法。

公开(公告)号：US20160002639A1

公开(公告)日：2016-01-07

申请号：US14796112

申请日：2015-07-10

Applicant: Rosetta Genomics Ltd.

Inventor： Issac Bentwich ,  Amir Avniel ,  Ranit Aharonov ,  Yael Karov ,  Yonat Shemer-Avni ,  Asaf Levy

IPC: C12N15/113

CPC classification number: C12N15/1133 ,  A61K48/00 ,  C12N15/113 ,  C12N15/1131 ,  C12N15/1132 ,  C12N2310/141 ,  C12N2320/11 ,  C12N2330/10 ,  C12N2330/31 ,  C12N2710/16022 ,  C12N2760/16122 ,  C12N2760/18522

Abstract: The invention provides isolated viral and human nucleic acids associated with viral infection and various nucleic acid molecules relating thereto or derived therefrom. The nucleic acids are useful for prevention, treatment and diagnosis of viral infections.

Abstract translation: 本发明提供了与病毒感染相关的分离的病毒和人核酸以及与之相关的或从其衍生的各种核酸分子。 核酸可用于病毒感染的预防，治疗和诊断。