公开(公告)号：US20140017780A1

公开(公告)日：2014-01-16

申请号：US13986516

申请日：2013-05-08

Applicant: ROSETTA GENOMICS LTD

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12N15/113

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

Abstract translation: 本文描述了与前列腺和肺癌相关的新型多核苷酸。 多核苷酸是miRNA和miRNA前体。 公开了可用于诊断，预后和治疗这些医疗条件的相关方法和组合物。 本文还描述了可用于鉴定前列腺和肺癌调节剂的方法。

公开(公告)号：US09890382B2

公开(公告)日：2018-02-13

申请号：US15586783

申请日：2017-05-04

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12N15/11 ,  C12N15/113 ,  C12Q1/68

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US20160047004A1

公开(公告)日：2016-02-18

申请号：US14797381

申请日：2015-07-13

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12Q1/70 ,  C12N15/113

CPC classification number: C12Q1/701 ,  C12N15/111 ,  C12N15/1131 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2320/10 ,  C12N2320/30 ,  C12N2330/10 ,  C12N2710/16222 ,  C12Q2600/136

Abstract: Described herein are novel polynucleotides associated with viral infections. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of viral infections.

Abstract translation: 本文描述的是与病毒感染相关的新型多核苷酸。 多核苷酸是miRNA和miRNA前体。 公开了可用于诊断，预后和治疗这些医疗条件的相关方法和组合物。 本文还描述了可用于鉴定病毒感染调节剂的方法。

公开(公告)号：US20190010491A1

公开(公告)日：2019-01-10

申请号：US15732957

申请日：2018-01-16

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12N15/113 ,  C12Q1/6886

Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods ad compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US20170240894A1

公开(公告)日：2017-08-24

申请号：US15586783

申请日：2017-05-04

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12N15/113 ,  C12Q1/68

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US20170226510A1

公开(公告)日：2017-08-10

申请号：US15731118

申请日：2017-04-21

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12N15/113 ,  C12Q1/68

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US20170298447A1

公开(公告)日：2017-10-19

申请号：US15586747

申请日：2017-05-04

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12Q1/68 ,  A61K38/00 ,  C12N15/11 ,  C12N15/113

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US09650680B2

公开(公告)日：2017-05-16

申请号：US14999879

申请日：2016-07-13

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12N15/11 ,  C07H21/04 ,  C12Q1/68 ,  A61K38/00 ,  C12N15/113

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US09650679B2

公开(公告)日：2017-05-16

申请号：US14756185

申请日：2015-08-13

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C07H21/04 ,  C12N15/11 ,  C12Q1/68 ,  A61K38/00 ,  C12N15/113

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

公开(公告)号：US20160319363A1

公开(公告)日：2016-11-03

申请号：US14999879

申请日：2016-07-13

Applicant: Rosetta Genomics Ltd.

Inventor： Itzhak Bentwich ,  Amir Avniel ,  Yael Karov ,  Ranit Aharonov

IPC: C12Q1/68

CPC classification number: C12N15/113 ,  A61K38/00 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/141 ,  C12N2310/531 ,  C12N2320/10 ,  C12N2320/11 ,  C12N2320/30 ,  C12N2330/10 ,  C12Q1/6809 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/178 ,  Y02A90/26

Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.

Abstract translation: 本文描述了与前列腺和肺癌相关的新型多核苷酸。 多核苷酸是miRNA和miRNA前体。 公开了可用于诊断，预后和治疗这些医疗条件的相关方法和组合物。 本文还描述了可用于鉴定前列腺和肺癌调节剂的方法。