Single-use pH sensor for bioreactor applications

    公开(公告)号:US11667880B2

    公开(公告)日:2023-06-06

    申请号:US17194686

    申请日:2021-03-08

    Applicant: Rosemount Inc.

    CPC classification number: C12M41/26 C12M23/28 G01N27/302 G01N27/333

    Abstract: A pH sensor for a single-use container includes a plunger sleeve configured to couple to a flange of the single-use container. A plunger is axially movable within the plunger sleeve between a storage position and an operating position. A pH sensing element coupled to the plunger wherein the pH element is disposed within a storage chamber in the storage position and is configured to be exposed to an interior of the single-use container in the operating position. In one example, a temperature sensitive element is disposed within the pH sensor and configured to sense temperature proximate the pH sensing element. In another example, a lock member is coupled to the plunger, where the lock member has a locked position and an unlocked position, the lock member being configured to inhibit movement of the plunger when in the locked position. In yet another example, the plunger includes at least one filling channel that allows access to a reference fill chamber when the plunger is in a filling position.

    Solid state reference gel
    12.
    发明申请

    公开(公告)号:US20220146453A1

    公开(公告)日:2022-05-12

    申请号:US17095418

    申请日:2020-11-11

    Applicant: Rosemount Inc.

    Inventor: Jinbo Hu

    Abstract: A solid state gel for use in a pH sensor comprises a reaction product of water, a buffer system for adjusting pH of the gel when in a liquid state, polyethylene glycol or its derivatives as a gelling agent and a salt wherein the water, the buffer, the polyethylene glycol and a reference electrolyte salt when mixed while in a liquid state form a mixture that was subjected to Gamma irradiation to form the reaction product.

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