Single-use pH sensor for bioreactor applications

    公开(公告)号:US11046927B2

    公开(公告)日:2021-06-29

    申请号:US16277169

    申请日:2019-02-15

    Applicant: Rosemount Inc.

    Abstract: A pH sensor for a single-use container includes a plunger sleeve configured to couple to a flange of the single-use container. A plunger is axially movable within the plunger sleeve between a storage position and an operating position. A pH sensing element coupled to the plunger wherein the pH element is disposed within a storage chamber in the storage position and is configured to be exposed to an interior of the single-use container in the operating position. In one example, a temperature sensitive element is disposed within the pH sensor and configured to sense temperature proximate the pH sensing element. In another example, a lock member is coupled to the plunger, where the lock member has a locked position and an unlocked position, the lock member being configured to inhibit movement of the plunger when in the locked position. In yet another example, the plunger includes at least one filling channel that allows access to a reference fill chamber when the plunger is in a filling position.

    Solid state reference gel
    4.
    发明授权

    公开(公告)号:US11815487B2

    公开(公告)日:2023-11-14

    申请号:US17095418

    申请日:2020-11-11

    Applicant: Rosemount Inc.

    Inventor: Jinbo Hu

    CPC classification number: G01N27/4167 G01N27/301 G01N27/302

    Abstract: A solid state gel for use in a pH sensor comprises a reaction product of water, a buffer system for adjusting pH of the gel when in a liquid state, polyethylene glycol or its derivatives as a gelling agent and a salt wherein the water, the buffer, the polyethylene glycol and a reference electrolyte salt when mixed while in a liquid state form a mixture that was subjected to Gamma irradiation to form the reaction product.

    HIGH PRESSURE SINGLE-USE ELECTROCHEMICAL ANALYTICAL SENSOR

    公开(公告)号:US20220373502A1

    公开(公告)日:2022-11-24

    申请号:US17749619

    申请日:2022-05-20

    Applicant: Rosemount Inc

    Abstract: A single-use electrochemical analytical sensor is provided. The sensor includes a sensing electrode configured to contact process fluid and a reference chamber containing an electrolyte. A reference electrode is disposed in the electrolyte. A reference junction is configured to contact the process fluid and is further configured to generate a flow of electrolyte into the process fluid. The reference chamber is configured to be stored in a depressurized state and then pressurized prior to operation. A method of operating a single-use electrochemical sensor is also provided.

    SINGLE-USE PH SENSOR FOR BIOREACTOR APPLICATIONS

    公开(公告)号:US20210189319A1

    公开(公告)日:2021-06-24

    申请号:US17194686

    申请日:2021-03-08

    Applicant: Rosemount Inc.

    Abstract: A pH sensor for a single-use container includes a plunger sleeve configured to couple to a flange of the single-use container. A plunger is axially movable within the plunger sleeve between a storage position and an operating position. A pH sensing element coupled to the plunger wherein the pH element is disposed within a storage chamber in the storage position and is configured to be exposed to an interior of the single-use container in the operating position. In one example, a temperature sensitive element is disposed within the pH sensor and configured to sense temperature proximate the pH sensing element. In another example, a lock member is coupled to the plunger, where the lock member has a locked position and an unlocked position, the lock member being configured to inhibit movement of the plunger when in the locked position. In yet another example, the plunger includes at least one filling channel that allows access to a reference fill chamber when the plunger is in a filling position.

    SINGLE-USE PH SENSOR FOR BIOREACTOR APPLICATIONS

    公开(公告)号:US20190264161A1

    公开(公告)日:2019-08-29

    申请号:US16277169

    申请日:2019-02-15

    Applicant: Rosemount Inc.

    Abstract: A pH sensor for a single-use container includes a plunger sleeve configured to couple to a flange of the single-use container. A plunger is axially movable within the plunger sleeve between a storage position and an operating position. A pH sensing element coupled to the plunger wherein the pH element is disposed within a storage chamber in the storage position and is configured to be exposed to an interior of the single-use container in the operating position. In one example, a temperature sensitive element is disposed within the pH sensor and configured to sense temperature proximate the pH sensing element. In another example, a lock member is coupled to the plunger, where the lock member has a locked position and an unlocked position, the lock member being configured to inhibit movement of the plunger when in the locked position. In yet another example, the plunger includes at least one filling channel that allows access to a reference fill chamber when the plunger is in a filling position.

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