公开(公告)号：US20150329847A1

公开(公告)日：2015-11-19

申请号：US14716275

申请日：2015-05-19

Applicant: Samsung Electronics Co., Ltd.

Inventor： Jae Il Lee ,  Hye Yoon Kang ,  Dongkyu Shin ,  Jung Min Kim ,  Jungmin Lee

IPC: C12N9/64 ,  C07K14/00 ,  A61K38/03 ,  C07K4/00 ,  A61K38/16 ,  A61K39/395 ,  A61K38/48 ,  C07K16/28

CPC classification number: A61K38/03 ,  A61K38/00 ,  A61K38/482 ,  A61K39/3955 ,  C07K4/00 ,  C07K16/2863 ,  C07K2318/20 ,  C07K2319/00 ,  C07K2319/01 ,  C07K2319/035 ,  C07K2319/33 ,  C07K2319/50 ,  C07K2319/70 ,  C12N9/6467 ,  C12Y304/21079

Abstract: A fusion protein including granzyme B, a cell penetrating peptide, a cleavage site, and a targeting moiety, a composition for cell membrane penetration comprising the fusion protein, and an anticancer composition comprising the fusion protein.

Abstract translation: 包含粒酶B，细胞穿透肽，切割位点和靶向部分的融合蛋白，包含融合蛋白的细胞膜渗透用组合物和包含该融合蛋白的抗癌组合物。

公开(公告)号：US10244995B2

公开(公告)日：2019-04-02

申请号：US15657035

申请日：2017-07-21

Applicant: Samsung Electronics Co., Ltd.

Inventor： Ku-Il Jang ,  Jung Min Kim ,  Jae Won Nam ,  Seung Hwan Lee

IPC: A61B6/00 ,  A61B6/10

Abstract: Disclosed herein is a mobile x-ray imaging apparatus having an improved structure to prevent breakage of or damage to an x-ray detector. One or more damping units are installed at base plates of one or more slots. The one or more damping units minimize an impact that may be applied to one or more x-ray detectors in a process of storing the one or more x-ray detector in the one or more slots.

公开(公告)号：US09902758B2

公开(公告)日：2018-02-27

申请号：US15137942

申请日：2016-04-25

Applicant: Samsung Electronics Co., Ltd.

Inventor： Dongkyu Shin ,  Jung Min Kim ,  Kyoung Hu Lee ,  Jae Il Lee ,  Jung Wook Lee

IPC: A61K38/00 ,  A61P35/00 ,  C07K14/47

CPC classification number: C07K14/4746 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4702 ,  C07K2319/00

Abstract: A three-helix bundle protein, a polynucleotide encoding the three-helix bundle protein, a method of preparing the three-helix bundle protein, and a method of treating a cancer using the three-helix bundle protein.

公开(公告)号：US09573985B2

公开(公告)日：2017-02-21

申请号：US14615146

申请日：2015-02-05

Applicant: Samsung Electronics Co., Ltd.

Inventor： Jung-Hoon Lee ,  Eunji Kang ,  Jung Min Kim ,  Jung-Min Lee ,  Jae Il Lee

IPC: C07K14/47 ,  A61K38/00

CPC classification number: C07K14/4738 ,  A61K38/00

Abstract: A p16 protein variant; a polynucleotide encoding the p16 protein variant; a method for preparing the p16 protein variant; a pharmaceutical composition comprising the p16 protein variant; a method for preventing and/or treating cancer comprising administering the p16 protein variant to a subject; and use of the p16 protein variant in the prophylaxis and/or therapy of cancer.

Abstract translation: p16蛋白变体; 编码p16蛋白质变体的多核苷酸; 制备p16蛋白质变体的方法; 包含p16蛋白质变体的药物组合物; 一种用于预防和/或治疗癌症的方法，其包括将p16蛋白质变体施用于受试者; 以及在预防和/或治疗癌症中使用p16蛋白质变体。

公开(公告)号：US20160008480A1

公开(公告)日：2016-01-14

申请号：US14794542

申请日：2015-07-08

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Jae Il Lee ,  Soshin Ahn ,  Jung Min Kim ,  Jungmin Lee ,  Jung-Hoon Lee

IPC: A61K47/48 ,  A61K38/16 ,  C07K16/30

CPC classification number: C07K16/30 ,  A61K38/00 ,  A61K47/6851 ,  C07K14/47 ,  C07K16/2863 ,  C07K2318/20 ,  C07K2319/10 ,  C07K2319/33 ,  C07K2319/50

Abstract: A fusion protein including a targeting moiety, a cleavage site, and a cell membrane penetrating domain, a conjugate including the fusion protein and a bioactive molecule, and methods employing the fusion protein and the conjugate are provided.

Abstract translation: 提供了包含靶向部分，切割位点和细胞膜穿透结构域的融合蛋白，包含融合蛋白和生物活性分子的缀合物，以及使用融合蛋白和缀合物的方法。