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26 条记录 (耗时 0.038 秒)

    G-protein coupled receptors
    11.
    发明授权
    G-protein coupled receptors 失效
    G蛋白偶联受体

    公开(公告)号：US07084259B2

    公开(公告)日：2006-08-01

    申请号：US10633894

    申请日：2003-08-04

    申请人： Scott Powers ,  Jianxin Yang ,  Gene Cutler

    发明人： Scott Powers ,  Jianxin Yang ,  Gene Cutler

    IPC分类号： C07K16/28

    CPC分类号： C07K14/723

    摘要： The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.

    摘要翻译： 本发明提供了在乳腺癌细胞中扩增的四种新型G蛋白偶联受体的分离的核酸和氨基酸序列，这种受体的抗体，检测这种核酸和受体的方法，以及筛选G蛋白调节剂的方法 偶联受体。

    G-protein coupled receptors amplified in breast cancer
    12.
    发明授权
    G-protein coupled receptors amplified in breast cancer 失效
    G蛋白偶联受体在乳腺癌中扩增

    公开(公告)号：US06638733B1

    公开(公告)日：2003-10-28

    申请号：US09524730

    申请日：2000-03-14

    申请人： Scott Powers ,  Jianxin Yang ,  Gene Cutler

    发明人： Scott Powers ,  Jianxin Yang ,  Gene Cutler

    IPC分类号： C12N510

    CPC分类号： C07K14/723

    摘要： The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.

    摘要翻译： 本发明提供了在乳腺癌细胞中扩增的四种新型G蛋白偶联受体的分离的核酸和氨基酸序列，这种受体的抗体，检测这种核酸和受体的方法，以及筛选G蛋白调节剂的方法 偶联受体。

    G-protein coupled receptor BCA-GPCR-3
    13.
    发明授权
    G-protein coupled receptor BCA-GPCR-3 失效
    G蛋白偶联受体BCA-GPCR-3

    公开(公告)号：US06635741B1

    公开(公告)日：2003-10-21

    申请号：US09546986

    申请日：2000-04-11

    申请人： Scott Powers ,  Jianxin Yang ,  Gene Cutler

    发明人： Scott Powers ,  Jianxin Yang ,  Gene Cutler

    IPC分类号： C07K14705

    CPC分类号： C07K14/723

    摘要： The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.

    摘要翻译： 本发明提供了在乳腺癌细胞中扩增的四种新型G蛋白偶联受体的分离的核酸和氨基酸序列，这种受体的抗体，检测这种核酸和受体的方法，以及筛选G蛋白调节剂的方法 偶联受体。

    Railroad tie of non-homogeneous cross section useful in environments deleterious to timber
    14.
    发明授权
    Railroad tie of non-homogeneous cross section useful in environments deleterious to timber 有权
    非均匀横截面的铁路系带在对木材有害的环境中有用

    公开(公告)号：US08430334B1

    公开(公告)日：2013-04-30

    申请号：US13081271

    申请日：2011-04-06

    申请人： Jonathan Jaffe ,  Scott Powers

    发明人： Jonathan Jaffe ,  Scott Powers

    IPC分类号： E01B3/10 ,  B32B21/00

    CPC分类号： E01B3/46

    摘要： The disclosure provides a railroad tie including a core, a first sleeve encapsulating the core and a second sleeve encapsulating the first sleeve. The first sleeve includes fingers running parallel to a long axis of the core along a top surface and fingers running perpendicular to a long axis of the tie along elongated sides of the first sleeve.

    摘要翻译： 本公开提供了一种铁路系带，其包括芯，封装芯的第一套筒和封装第一套筒的第二套筒。 第一套筒包括沿着顶表面平行于芯的长轴平行延伸的指状物，并且指状物沿垂直于第一套筒的细长边缘的长轴线垂直地延伸。

    Printed-circuit impedance control using skewed reference mesh
    15.
    发明授权
    Printed-circuit impedance control using skewed reference mesh 失效
    使用偏斜参考网格的印刷电路阻抗控制

    公开(公告)号：US07504904B1

    公开(公告)日：2009-03-17

    申请号：US11397156

    申请日：2006-04-04

    申请人： Scott Powers ,  Sean M. McClain ,  Ernest B. Bogusch

    发明人： Scott Powers ,  Sean M. McClain ,  Ernest B. Bogusch

    IPC分类号： H01P3/08

    CPC分类号： H01P3/081 ,  H05K1/0224 ,  H05K1/0253 ,  H05K2201/09236 ,  H05K2201/09681

    摘要： A printed circuit laminate is provided comprising at least one conductor trace for carrying forward electrical signals in a first direction of signal propagation. The printed circuit laminate also comprises a mesh reference plane, spaced from the at least one conductor trace, for carrying return electrical signals in a second direction. The mesh reference plane defines a plurality of cells. Each cell of the plurality of cells includes at least one axis of repetition. The plurality of cells are configured so that all of the axes of repetition of each cell are different from the first direction of signal propagation. Furthermore, the frequency of cell repetition along the first direction of signal propagation is chosen to reduce differences in transmission line impedance between any two conductors on the same laminate or any two conductors on different laminates.

    摘要翻译： 提供了印刷电路层压板，其包括至少一个导体迹线，用于在信号传播的第一方向上传送电信号。 印刷电路层压板还包括与至少一个导体迹线间隔开的用于在第二方向上传送返回电信号的网格参考平面。 网格参考平面定义多个单元。 多个单元中的每个单元包括至少一个重复轴。 多个单元被配置为使得每个单元的所有重复轴不同于信号传播的第一方向。 此外，选择沿着信号传播的第一方向的单元重复的频率以减少同一层压板上的任何两个导体与不同层压板上的任何两个导体之间的传输线阻抗的差异。

    SENSORY FEEDBACK BED
    16.
    发明申请
    SENSORY FEEDBACK BED 审中-公开
    感应反馈床

    公开(公告)号：US20070262247A1

    公开(公告)日：2007-11-15

    申请号：US11463636

    申请日：2006-08-10

    申请人： Carlos Becerra ,  William K. Chandler ,  Scott Powers ,  Abebaw Zeleke

    发明人： Carlos Becerra ,  William K. Chandler ,  Scott Powers ,  Abebaw Zeleke

    IPC分类号： G01J5/08 ,  G02B6/00

    CPC分类号： G01K11/3206 ,  A61H2203/0456 ,  A61H2230/50 ,  A61H2230/62 ,  G01D5/35383 ,  G01K13/002 ,  G02B6/02195

    摘要： A mechanism for mapping an anatomical characteristic of a patient includes a treatment bed having a top surface. A fiber Bragg grating channel is disposed along at least a portion of the treatment bed near the top surface and includes a fiber optic waveguide defining a plurality of spaced-apart Bragg-type gratings. A multi-wavelength light source generates a beam that is in optical communication with the fiber Bragg grating channel. A detector, in optical communication with the fiber Bragg grating channel, detects reflections of light from at least one of the Bragg-type gratings. A computer is programmed to calculate at least one anatomical characteristic based on a characteristic of at least one of the reflection of light.

    摘要翻译： 用于映射患者的解剖特征的机构包括具有顶表面的治疗床。 纤维布拉格光栅通道沿着顶表面附近的治疗床的至少一部分设置，并且包括限定多个间隔开的布拉格型光栅的光纤波导。 多波长光源产生与光纤布拉格光栅通道光通信的光束。 与光纤布拉格光栅通道光通信的检测器检测来自布拉格型光栅中的至少一个的光的反射。 计算机被编程为基于光的至少一个的特性来计算至少一个解剖特征。

    Gene amplification in cancer
    18.
    发明授权
    Gene amplification in cancer 失效
    癌症中的基因扩增

    公开(公告)号：US06974672B2

    公开(公告)日：2005-12-13

    申请号：US10390191

    申请日：2003-03-18

    申请人： Scott Powers ,  Jianxin Yang

    发明人： Scott Powers ,  Jianxin Yang

    IPC分类号： A61K48/00 ,  C07H21/02 ,  C07H21/04 ,  C12M1/34 ,  C12P19/34 ,  C12Q1/68 ,  G01N33/574

    CPC分类号： C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/156 ,  Y10T436/143333

    摘要： There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the CTSZ and CD24 genes, which are amplified colon cancer and/or ovarian cancer and/or breast cancer genes. The CTSZ and CD24 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vaccine; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

    摘要翻译： 公开了利用扩增的结肠癌和/或卵巢癌和/或乳腺癌基因的CTSZ和CD24基因来诊断，预防和治疗哺乳动物（例如人）中的肿瘤和癌症的方法和组合物。 CTSZ和CD24基因，其表达的蛋白质产物和抗体用于诊断或作为癌症治疗或疫苗的靶标; 它们也用于鉴定可用于癌症诊断，预防和治疗的化合物和试剂。

    SODD gene expression in cancer
    19.
    发明授权
    SODD gene expression in cancer 失效
    SODD基因在癌症中的表达

    公开(公告)号：US06372444B1

    公开(公告)日：2002-04-16

    申请号：US09417559

    申请日：1999-10-13

    申请人： Scott Powers ,  Rong Wendy Zeng

    发明人： Scott Powers ,  Rong Wendy Zeng

    IPC分类号： G01N33574

    CPC分类号： G01N33/57484 ,  C12Q1/6886 ,  C12Q2600/136

    摘要： The invention provides methods and compositions for diagnosing and treating tumors. In particular embodiments, the invention provides methods for characterizing tumors for SODD gene copy number and/or expression and for using this diagnosis in guiding treatment options. Accordingly, the invention provides methods for biasing therapeutic options by (a) contacting a biopsy of a tumor with an agent which specifically binds a SODD gene or SODD gene product thereof; (b) measuring specific binding of the agent to the SODD gene or gene product to determine an amount of the SODD gene or gene product present in the biopsy; and (c) biasing therapeutic options for treating the tumor based on the amount of the SODD gene or gene product present in the biopsy.

    摘要翻译： 本发明提供了用于诊断和治疗肿瘤的方法和组合物。 在具体实施方案中，本发明提供了用于表征SODD基因拷贝数和/或表达的肿瘤的方法，以及在指导治疗选择中使用该诊断的方法。 因此，本发明提供了通过（a）使肿瘤的活组织检查与特异性结合SODD基因或SODD基因产物的试剂接触来偏置治疗选择的方法; （b）测定试剂与SODD基因或基因产物的特异性结合，以确定活检中存在的SODD基因或基因产物的量; 和（c）基于活检中存在的SODD基因或基因产物的量来偏置用于治疗肿瘤的治疗选择。

    MACHINE LEARNING AND COMPUTER VISION BASED 3D PRINTER MONITORING SYSTEMS AND RELATED METHODS
    20.
    发明申请
    MACHINE LEARNING AND COMPUTER VISION BASED 3D PRINTER MONITORING SYSTEMS AND RELATED METHODS 有权

    公开(公告)号：US20220230292A1

    公开(公告)日：2022-07-21

    申请号：US17579946

    申请日：2022-01-20

    申请人： Scott Powers

    发明人： Scott Powers

    IPC分类号： G06T7/00 ,  G05B19/418 ,  B33Y50/02

    摘要： Machine learning and computer vision based systems and methods for three-dimensional (3D) printer monitoring are described herein. An example method includes receiving an image of an object during a 3D printing process; determining a printing property associated with the object based upon the image of the object; inputting the printing property associated with the object into a machine learning module; and predicting, using the machine learning module, a 3D printing error.