公开(公告)号：US09840471B2

公开(公告)日：2017-12-12

申请号：US14768146

申请日：2014-02-19

Applicant: Senomyx, Inc.

Inventor： Lyudmyla Chumakova ,  Andrew Patron ,  Chad Priest ,  Donald Karanewsky ,  Rachel Kimmich ,  Brant Clayton Boren ,  Jeffrey Robert Hammaker ,  Volodymyr Chumakov ,  Wen Zhao ,  Alain Noncovich ,  Jane Ung

IPC: C07D231/20 ,  C07D405/06 ,  C07D403/06 ,  C07D401/06 ,  C07D239/22 ,  C07D213/50 ,  C07D409/06 ,  C07D207/333 ,  C07D333/22 ,  C07D233/78 ,  C07D235/02 ,  C07D207/32 ,  A23L2/52 ,  C07C233/31 ,  C07D207/26 ,  C07D239/62 ,  A23L33/10

CPC classification number: C07D231/20 ,  A23L2/52 ,  A23L33/10 ,  A23V2002/00 ,  C07C233/31 ,  C07C2601/04 ,  C07C2601/14 ,  C07C2601/16 ,  C07D207/26 ,  C07D207/32 ,  C07D207/333 ,  C07D213/50 ,  C07D233/78 ,  C07D235/02 ,  C07D239/22 ,  C07D239/62 ,  C07D333/22 ,  C07D401/06 ,  C07D403/06 ,  C07D405/06 ,  C07D409/06

Abstract: The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.

公开(公告)号：US20170096418A1

公开(公告)日：2017-04-06

申请号：US15282432

申请日：2016-09-30

Applicant: Senomyx, Inc.

Inventor： Andrew P. Patron ,  Alain Noncovich ,  Jane Ung ,  Timothy Davis ,  Joseph R. Fotsing ,  Chad Priest ,  Catherine Tachdjian

IPC: C07D409/12 ,  A61K9/00 ,  A61K31/4155

CPC classification number: C07D409/12 ,  A61K9/0014 ,  A61K31/4155

Abstract: The present disclosure relates to compounds which are useful as cooling sensation compounds.