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公开(公告)号:US10016418B2
公开(公告)日:2018-07-10
申请号:US15205608
申请日:2016-07-08
Applicant: Senomyx, Inc.
Inventor: Chad Priest , Alain Noncovich , Andrew Patron , Jane Ung
IPC: A61K31/497 , A61K31/165 , A61K31/381 , A61K31/4155 , A61K31/415 , A61K31/422 , A61K31/426 , A61K31/437 , A61K31/4409 , A61K31/4436 , C07C233/11 , C07C235/20 , C07C235/24 , C07C235/34 , C07D213/40 , C07D213/75 , C07D231/40 , C07D277/28 , C07D307/52 , C07D333/20 , C07D333/24 , C07D333/32 , C07D405/12 , C07D407/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D471/04 , A61K8/42 , A61K8/49 , A61K8/69 , A61Q19/00 , A01N43/10 , A01N43/40 , A01N43/56 , A01N43/60 , A01N43/76 , A01N43/80 , A01N43/90 , A23L27/00 , A23L33/10 , A01N37/18 , A01N43/78 , A61Q1/02 , A61Q5/02 , A61Q5/12 , A61Q9/02 , A61Q11/00 , A61Q15/00 , A61Q17/02 , A61Q17/04 , A61Q19/10
CPC classification number: A61K31/497 , A01N37/18 , A01N43/10 , A01N43/40 , A01N43/56 , A01N43/60 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/90 , A23L27/88 , A23L33/10 , A23V2002/00 , A61K8/42 , A61K8/49 , A61K8/4926 , A61K8/494 , A61K8/4973 , A61K8/4986 , A61K8/69 , A61K31/165 , A61K31/381 , A61K31/415 , A61K31/4155 , A61K31/422 , A61K31/426 , A61K31/437 , A61K31/4409 , A61K31/4436 , A61K2800/10 , A61K2800/40 , A61Q1/02 , A61Q5/02 , A61Q5/12 , A61Q9/02 , A61Q11/00 , A61Q15/00 , A61Q17/02 , A61Q17/04 , A61Q19/00 , A61Q19/001 , A61Q19/10 , C07C233/11 , C07C235/20 , C07C235/24 , C07C235/34 , C07C2601/14 , C07D213/40 , C07D213/75 , C07D231/40 , C07D277/28 , C07D307/52 , C07D333/20 , C07D333/24 , C07D333/32 , C07D405/12 , C07D407/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D471/04
Abstract: The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formula (I) and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.
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公开(公告)号:US20160339026A1
公开(公告)日:2016-11-24
申请号:US14874258
申请日:2015-10-02
Applicant: Senomyx, Inc.
Inventor: Alain Noncovich , Jane Ung , Timothy Davis , Joseph R. Fotsing , Rachel D.A. Kimmich , Chad Priest , Donald S. Karanewsky , Lyudmyla Chumakova , Andrew Patron , Paul Brust , Guy Servant
IPC: A61K31/515 , A61K31/4155 , A61K31/4152 , A61K31/4406 , A61K31/513 , A61K31/4166 , A61K31/165 , A61K9/00 , A61K31/4439
CPC classification number: A61K31/515 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/494 , A61K8/4953 , A61K8/4986 , A61K9/0014 , A61K31/165 , A61K31/381 , A61K31/40 , A61K31/4152 , A61K31/4162 , A61K31/4166 , A61K31/4245 , A61K31/427 , A61K31/4439 , A61K31/513 , A61K2800/244 , A61Q19/00
Abstract: The present disclosure relates to topical compositions comprising one or more compounds which are cooling agents.
Abstract translation: 本公开涉及包含一种或多种作为冷却剂的化合物的局部组合物。
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公开(公告)号:US09732071B2
公开(公告)日:2017-08-15
申请号:US15282432
申请日:2016-09-30
Applicant: Senomyx, Inc.
Inventor: Andrew P. Patron , Alain Noncovich , Jane Ung , Timothy Davis , Joseph R. Fotsing , Chad Priest , Catherine Tachdjian
IPC: C07D409/12 , A61K31/4155 , A61K9/00
CPC classification number: C07D409/12 , A61K9/0014 , A61K31/4155
Abstract: The present disclosure relates to compounds which are useful as cooling sensation compounds.
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公开(公告)号:US20150376136A1
公开(公告)日:2015-12-31
申请号:US14768146
申请日:2014-02-19
Applicant: SENOMYX, INC.
Inventor: Lyudmyla Chumakova , Andrew Patron , Chad Priest , Donald Karanewsky , Rachel Kimmich , Brant Clayton Boren , Jeffrey Robert Hammaker , Volodymyr Chumakov , Wen Zhao , Alain Noncovich , Jane Ung
IPC: C07D231/20 , C07D405/06 , C07D403/06 , C07D401/06 , C07D239/22 , A23L2/52 , C07C233/31 , C07D213/50 , C07D333/22 , C07D207/26 , C07D207/333 , A23L1/30 , C07D409/06 , C07D239/62
CPC classification number: C07D231/20 , A23L2/52 , A23L33/10 , A23V2002/00 , C07C233/31 , C07C2601/04 , C07C2601/14 , C07C2601/16 , C07D207/26 , C07D207/32 , C07D207/333 , C07D213/50 , C07D233/78 , C07D235/02 , C07D239/22 , C07D239/62 , C07D333/22 , C07D401/06 , C07D403/06 , C07D405/06 , C07D409/06
Abstract: The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.
Abstract translation: 本发明包括可用作TRPM8的调节剂的化合物,例如式(Ia),(Ib)和(Ic)的化合物及其亚属及其物质; 含有这些化合物的个人产品; 以及这些化合物和个人产品的使用,特别是使用增加或诱导化学感觉,例如冷却或冷感觉。
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公开(公告)号:US10392371B2
公开(公告)日:2019-08-27
申请号:US15764204
申请日:2016-09-21
Applicant: Senomyx, Inc.
Inventor: Andrew P. Patron , Alain Noncovich , Timothy Davis , Chad Priest , Joseph R. Fotsing , Jane Ung , Catherine Tachdjian
IPC: C07D409/12 , A61K9/00 , A61K31/4155 , A23L33/10 , A23L2/52 , B65D65/38 , B65D81/18
Abstract: Provided herein are compounds which are useful as cooling sensation compounds.
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公开(公告)号:US20190177308A9
公开(公告)日:2019-06-13
申请号:US15764204
申请日:2016-09-21
Applicant: Senomyx, Inc.
Inventor: Andrew P. Patron , Alain Noncovich , Timothy Davis , Chad Priest , Joseph R. Fotsing , Jane Ung , Catherine Tachdjian
IPC: C07D409/12 , A23L33/10 , A23L2/52 , B65D81/18 , B65D65/38
CPC classification number: C07D409/12 , A23L2/52 , A23L33/10 , A23V2002/00 , A61K9/0014 , A61K31/4155 , B65D65/38 , B65D81/18
Abstract: The present disclosure relates to compounds which are useful as cooling sensation compounds.
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公开(公告)号:US20170369447A1
公开(公告)日:2017-12-28
申请号:US15697301
申请日:2017-09-06
Applicant: Senomyx, Inc.
Inventor: Lyudmyla Chumakova , Andrew Patron , Chad Priest , Donald Karanewsky , Rachel Kimmich , Brant Clayton Boren , Jeffrey Robert Hammaker , Volodymyr Chumakov , Wen Zhao , Alain Noncovich , Jane Ung
IPC: C07D231/20 , A23L33/10 , C07D403/06 , C07D401/06 , C07D333/22 , C07D239/62 , C07D239/22 , C07D235/02 , C07D233/78 , C07D213/50 , C07D207/333 , C07D207/32 , C07D207/26 , C07C233/31 , C07D405/06 , A23L2/52 , C07D409/06 , C07C2601/04 , C07C2601/16
Abstract: The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.
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公开(公告)号:US20160317532A1
公开(公告)日:2016-11-03
申请号:US15205608
申请日:2016-07-08
Applicant: Senomyx, Inc.
Inventor: Chad Priest , Alain Noncovich , Andrew Patron , Jane Ung
IPC: A61K31/497 , A61K8/49 , A01N43/56 , A61K31/422 , A01N43/76 , A01N43/80 , A61K31/381 , A01N43/10 , A61K31/4436 , A01N43/40 , A61K31/415 , A61K31/426 , A01N43/78 , A61K31/165 , A61K8/42 , A01N37/18 , A01N43/60 , A61K31/4409 , A61K31/437 , A01N43/90 , A61Q19/00 , A23L33/10 , A23L27/00 , A61K31/4155
CPC classification number: A61K31/497 , A01N37/18 , A01N43/10 , A01N43/40 , A01N43/56 , A01N43/60 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/90 , A23L27/88 , A23L33/10 , A23V2002/00 , A61K8/42 , A61K8/49 , A61K8/4926 , A61K8/494 , A61K8/4973 , A61K8/4986 , A61K8/69 , A61K31/165 , A61K31/381 , A61K31/415 , A61K31/4155 , A61K31/422 , A61K31/426 , A61K31/437 , A61K31/4409 , A61K31/4436 , A61K2800/10 , A61K2800/40 , A61Q1/02 , A61Q5/02 , A61Q5/12 , A61Q9/02 , A61Q11/00 , A61Q15/00 , A61Q17/02 , A61Q17/04 , A61Q19/00 , A61Q19/001 , A61Q19/10 , C07C233/11 , C07C235/20 , C07C235/24 , C07C235/34 , C07C2601/14 , C07D213/40 , C07D213/75 , C07D231/40 , C07D277/28 , C07D307/52 , C07D333/20 , C07D333/24 , C07D333/32 , C07D405/12 , C07D407/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D471/04
Abstract: The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formula (I) and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.
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公开(公告)号:US20180289704A1
公开(公告)日:2018-10-11
申请号:US15994235
申请日:2018-05-31
Applicant: SENOMYX, INC.
Inventor: Chad Priest , Alain Noncovich , Andrew Patron , Jane Ung
IPC: A61K31/497 , C07C233/11 , A61K31/165 , A61K31/381 , A61K31/415 , A61K31/4155 , A61K31/422 , A61K31/426 , A61K31/437 , A61K31/4409 , A61K31/4436 , A23L33/10 , A01N37/18 , A01N43/78 , A23L27/00 , C07D409/12 , A01N43/90 , A01N43/56 , A01N43/60 , A01N43/76 , A01N43/80 , A61K8/49 , A01N43/10 , A01N43/40
Abstract: The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formula (I) and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.
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公开(公告)号:US20180273517A1
公开(公告)日:2018-09-27
申请号:US15764204
申请日:2016-09-21
Applicant: Senomyx, Inc.
Inventor: Andrew P. Patron , Alain Noncovich , Timothy Davis , Chad Priest , Joseph R. Fotsing , Jane Ung , Catherine Tachdjian
IPC: C07D409/12 , A23L33/10 , A23L2/52 , B65D81/18 , B65D65/38
CPC classification number: C07D409/12 , A23L2/52 , A23L33/10 , A23V2002/00 , A61K9/0014 , A61K31/4155 , B65D65/38 , B65D81/18
Abstract: The present disclosure relates to compounds which are useful as cooling sensation compounds.
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