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20 条记录 (耗时 0.029 秒)

    Mannitol/hydrogel cap for tissue-insertable connections
    11.
    发明授权
    Mannitol/hydrogel cap for tissue-insertable connections 有权
    用于组织可插入连接的甘露醇/水凝胶帽

    公开(公告)号：US06360129B1

    公开(公告)日：2002-03-19

    申请号：US09459782

    申请日：1999-12-13

    申请人： Gregory R. Ley ,  Larry L. Hum

    发明人： Gregory R. Ley ,  Larry L. Hum

    IPC分类号： A61N100

    CPC分类号： A61N1/0573 ,  A61N2001/058

    摘要： A helical element for insertion into tissue comprises a helical element having an insertion end, a protruding end and an open central area within the wire, rods, filaments, cables or the like that form the helix. The helical element has at least its insertion end covered by a cap of a water-soluble or water-dispersible composition. The composition of the cap comprises a water-soluble or water dispersible component having a hydrogel mixed therein. In one embodiment, there is either a hollow area within the composition within the open central area or the material is more porous than the remaining material. The helical element preferably comprises an electrical lead, such as a positive endocardial lead, with an electrode at the protruding or distal end of the lead. The helical element may comprise any biocompatable material with sufficient structural integrity to provide a secure attachment to tissue in a patient. Where the helical element is also to provide an active (electrically active) function, the composition of the helical element should also be electrically conductive.

    摘要翻译： 用于插入组织的螺旋元件包括螺旋元件，其具有插入端，突出端和形成螺旋的线内的开口中心区域，杆，细丝，电缆等。 螺旋元件的至少其插入端被水溶性或水分散性组合物的盖子覆盖。 盖的组成包括其中混合有水凝胶的水溶性或水分散性组分。 在一个实施方案中，组合物中的中空区域在开放中心区域内，或者材料比剩余材料更多孔。 螺旋元件优选地包括电引线，例如正性心内膜引线，在引线的突出或远端具有电极。螺旋元件可以包括具有足够结构完整性的任何可生物相容的材料，以提供与 患者。 当螺旋元件也提供活性（电活性）功能时，螺旋元件的组成也应当是导电的。

    System and apparatus having low profile collapsible tines
    12.
    发明授权
    System and apparatus having low profile collapsible tines 失效
    具有低轮廓可折叠齿的系统和装置

    公开(公告)号：US06240322B1

    公开(公告)日：2001-05-29

    申请号：US09186326

    申请日：1998-11-04

    申请人： Randall M. Peterfeso ,  Mary Lee Cole ,  Larry L. Hum ,  Michael P. Campbell

    发明人： Randall M. Peterfeso ,  Mary Lee Cole ,  Larry L. Hum ,  Michael P. Campbell

    IPC分类号： A61N105

    CPC分类号： A61N1/057

    摘要： A medical device is insertable and/or implantable into a body of a patient. The medical device includes a plurality of hollow and/or collapsible tines which are adapted to assist in deployment of the medical device into the body and in preventing inadvertent removal or dislodging of the medical device from the body. The tines are coupled to the medical device body at a coupling end and extend away from the device to a free end. The tines can have a number of configurations such as cylindrical or cone shaped. In addition, the cross section of the free end of the tines can be elliptical, where the free end extends to a tip. Another cross section includes a semi-circle including an open portion which can face towards or away from the medical device body. The tines also include coiled structures which can have a radial axis perpendicular to the radial axis of the medical device.

    摘要翻译： 医疗装置可插入和/或植入患者体内。 医疗装置包括多个中空和/或可收缩的齿，其适于帮助将医疗装置部署到体内并防止医疗装置从体内无意中移除或移走。 齿在耦合端耦合到医疗装置本体并且远离装置延伸到自由端。 齿可以具有多个构造，例如圆柱形或锥形。 此外，齿的自由端的横截面可以是椭圆形，其中自由端延伸到尖端。 另一横截面包括一个半圆，其包括可面向或远离医疗装置主体的开放部分。 齿还包括可以具有垂直于医疗装置的径向轴线的径向轴线的螺旋结构。

    Expandable seal for use with medical device and system
    13.
    发明授权
    Expandable seal for use with medical device and system 有权
    用于医疗设备和系统的可扩展密封件

    公开(公告)号：US06240321B1

    公开(公告)日：2001-05-29

    申请号：US09133310

    申请日：1998-08-12

    申请人： Aaron W. Janke ,  Larry L. Hum ,  Randy Westlund ,  Ronald W. Heil, Jr. ,  Bruce Tockman

    发明人： Aaron W. Janke ,  Larry L. Hum ,  Randy Westlund ,  Ronald W. Heil, Jr. ,  Bruce Tockman

    IPC分类号： A61N105

    CPC分类号： A61N1/0573 ,  A61N1/0565

    摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.

    摘要翻译： 适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。 引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。 引线可以包括用于将电极固定到心脏组织的固定螺旋。 导线组件可以替代地包括开放的管腔引线端头。 在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。 密封件包括可膨胀基质，例如水凝胶。 当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。 密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。 结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

    SURFACE MODIFICATION TO IMPROVE LUBRICITY, ABRASION RESISTANCE AND TEMPERATURE RESILIENCE OF LEADS
    14.
    发明申请
    SURFACE MODIFICATION TO IMPROVE LUBRICITY, ABRASION RESISTANCE AND TEMPERATURE RESILIENCE OF LEADS 审中-公开
    表面改性以提高导线的润滑性，耐磨性和温度耐久性

    公开(公告)号：US20130122185A1

    公开(公告)日：2013-05-16

    申请号：US13735530

    申请日：2013-01-07

    申请人： Shrojalkumar Desai ,  Leslie J. Carion ,  Larry L. Hum

    发明人： Shrojalkumar Desai ,  Leslie J. Carion ,  Larry L. Hum

    IPC分类号： B05D5/08

    CPC分类号： B05D5/08 ,  A61L31/10 ,  A61L31/14 ,  A61L2400/18 ,  C08J3/245 ,  C08J7/06 ,  C08L23/0853 ,  C08L83/04 ,  C08L2666/04

    摘要： A medical electrical lead body having an outer surface and including at least one lumen having an inner surface treated with a silane surface modifying agent to form a three-dimensional, densely cross-linked lubricious coating over at least a portion of the inner surface of the lumen. The outer surface of the lead body also may be similarly treated. The lubricious silane coating may reduce the coefficient of friction of the coated surface of the lead body by as much as 80% when compared to an uncoated surface. A reduction in the coefficient of friction may enhance the stringing efficiency of a conductor through the lead body lumen and may enhance its abrasion resistance.

    摘要翻译： 一种具有外表面并且包括具有用硅烷表面改性剂处理的内表面的至少一个内腔的医疗电引线体，以在所述内表面的至少一部分上形成三维密集交联的光滑涂层 流明。 引线体的外表面也可以被类似地处理。 与未涂覆的表面相比，润滑硅烷涂层可以将引线体的涂覆表面的摩擦系数降低多达80％。 摩擦系数的降低可以提高导体通过引线体腔的穿线效率并且可以提高其耐磨性。

    SOLVENTLESS METHOD FOR FORMING A COATING ON A MEDICAL ELECTRICAL LEAD BODY
    15.
    发明申请
    SOLVENTLESS METHOD FOR FORMING A COATING ON A MEDICAL ELECTRICAL LEAD BODY 有权
    用于在医用电导体上形成涂层的无溶剂方法

    公开(公告)号：US20110052787A1

    公开(公告)日：2011-03-03

    申请号：US12832635

    申请日：2010-07-08

    申请人： Larry L. Hum ,  James Q. Feng ,  Arienne P. Simon ,  Tolga Tas

    发明人： Larry L. Hum ,  James Q. Feng ,  Arienne P. Simon ,  Tolga Tas

    IPC分类号： B05D3/00

    CPC分类号： A61L31/16 ,  A61L31/10 ,  A61L31/18 ,  C09D5/38 ,  C08L83/04

    摘要： A solventless method for forming a coating on a medical electrical lead is described. The method includes combining particles of a therapeutic agent with a polymeric material in a flowable form in the absence of a solvent to form a uniform suspension. A predetermined amount of the suspension is dispensed onto a portion of the lead and is then cured to form the therapeutic agent eluting layer. Additional layers such as a primer layer, fluoro-opaque layer and/or a topcoat layer can be formed using the solventless method. Employing a solventless method may avoid contraction of the layer being formed due to solvent evaporation during the curing process, and may facilitate greater control over the thickness of the therapeutic agent eluting coating.

    摘要翻译： 描述了用于在医用电线上形成涂层的无溶剂方法。 该方法包括在不存在溶剂的情况下将治疗剂的颗粒与可流动形式的聚合物材料组合以形成均匀的悬浮液。 将预定量的悬浮液分配到引线的一部分上，然后固化以形成治疗剂洗脱层。 可以使用无溶剂法形成附加层，例如底漆层，氟不透明层和/或顶涂层。 使用无溶剂方法可以避免在固化过程中由于溶剂蒸发而形成的层的收缩，并且可以有助于更好地控制治疗剂洗脱涂层的厚度。

    Sealing assembly for intravenous lead
    18.
    发明授权
    Sealing assembly for intravenous lead 有权
    密封组件用于静脉引导

    公开(公告)号：US06901288B2

    公开(公告)日：2005-05-31

    申请号：US09970195

    申请日：2001-10-02

    申请人： Aaron W. Janke ,  Larry L. Hum ,  Randy Westlund ,  Ronald W. Heil, Jr. ,  Bruce Tockman

    发明人： Aaron W. Janke ,  Larry L. Hum ,  Randy Westlund ,  Ronald W. Heil, Jr. ,  Bruce Tockman

    IPC分类号： A61N1/05 ,  A61N1/362

    CPC分类号： A61N1/0573 ,  A61N1/0565

    摘要： A seal adapted for use with medical devices is provided with a lead having a distal tip electrode. The distal tip of the lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The lead can include a fixation helix for securing the electrode to cardiac tissue. The lead assembly can alternatively include an open lumen lead tip. A seal is provided within the lead tip assembly such that the seal is expanded to prevent or limit further entry of fluids through the lead tip. The seal includes an expandable matrix, such as a hydrogel. The seal is formed on or within the lead when the lead and the seal comes into contact with a fluid and expands. The seal is also formed as a plug which is deployed through the medical device, and expands as the plug absorbs fluid. A housing incorporating the seal can also be attached to a portion of the medical device to provide the seal.

    摘要翻译： 适于与医疗装置一起使用的密封件设置有具有远端尖端电极的引线。 引线的远端适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。 引线可以包括用于将电极固定到心脏组织的固定螺旋。 导线组件可以替代地包括开放的管腔引线端头。 在引线端头组件内设置密封件，使得密封件被膨胀以防止或限制流体进一步通过引线头进入。 密封件包括可膨胀基质，例如水凝胶。 当铅和密封件与流体接触并膨胀时，密封件形成在引线上或内部。 密封件还形成为通过医疗装置展开的塞子，并且当塞子吸收流体时膨胀。 结合密封件的壳体也可以附接到医疗装置的一部分以提供密封。

    Lubricious, wear resistant surface coating by plasma polymerization
    19.
    发明授权
    Lubricious, wear resistant surface coating by plasma polymerization 有权

    公开(公告)号：US06506457B2

    公开(公告)日：2003-01-14

    申请号：US09822946

    申请日：2001-03-30

    申请人： Larry L. Hum

    发明人： Larry L. Hum

    IPC分类号： C08J718

    CPC分类号： B05D1/62 ,  B05D5/083 ,  B05D2201/00

    摘要： The present methods provide an amorphous, conformal, protective, abrasion-resistant, lubricious fluoropolymer coating on to a polymer substrate via a gas plasma deposition method. The coating method, according to one embodiment of the method, involves generating a gas plasma by introducing a mixture of a fluorinated gas monomer and a hydrocarbon gas into an energetic ion field, such as an ion beam or the field produced by a radio-frequency source. The fluorinated gas monomer is selected from the group consisting of CF.sub.4, C.sub.2 F.sub.4, C.sub.2 F.sub.6, CF.sub.3.sub.2CO, CH.sub.2 CF.sub.2 and mixtures of the foregoing. The hydrocarbon gas is selected from the group consisting of C.sub.2 H.sub.2, C.sub.2 H.sub.4, C.sub.2 H.sub.6, and H.sub.2 and mixtures of the foregoing. The polymer substrate is exposed to the foregoing gas plasma for sufficient time to achieve the desired coating thickness.