摘要:
A coating for an ink jet printhead front face, wherein the coating comprises a oleophobic low adhesion coating. When the oleophobic low adhesion coating is disposed on an ink jet printhead front face surface, jetted drops of ultra-violet gel ink or jetted drops of solid ink exhibit a contact angle greater than 45° and a low sliding angle of less than about 30°. In embodiments, the oleophobic low adhesion coating is thermally stable wherein the surface contact angle and sliding angle show little degradation after the coating is subjected to high temperatures in a range between 180° and 320° or thereabout and high pressures in a range between 100 psi and 400 psi or thereabout during printhead fabrication and manufacturing.
摘要:
An aperture plate for a print head of a printer can include a first layer having a first emissivity which is covered by a second layer having a second emissivity which is less than the first emissivity. In an embodiment, the second layer can be etched at nozzle locations to form openings in the second layer which have widths/areas greater than widths/areas of nozzles formed in the first layer. In another embodiment, the second layer can have a smaller thickness at the nozzle locations and a larger thickness away from the nozzle locations. Forming the openings in the second layer which are larger than the nozzles, or forming the second layer thinner at the nozzle locations prior to forming the nozzles, can provide a well-formed nozzle and an aperture plate having a low emissivity.
摘要:
There is described a portable electronic device capable of managing screen orientation. The portable electronic device comprises a display, a motion sensor, an image sensor and a processor. The display provides an image at a first orientation. The motion sensor attempts to detect a rotation of the portable electronic device. The image sensor attempts to detect one or more body features. The processor determines a second orientation of the image at the display based on the rotation detected at the motion sensor and/or the body feature or features detected at the image sensor. The portable electronic device may determine an orientation of the image at the display in response to detecting the rotation at the motion sensor and/or the body feature or features at the image sensor.
摘要:
A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52.
摘要:
Exemplary embodiments provide materials and methods for a printer member used in ink-jet marking systems that can include a layer electrospun over an aluminum roller to facilitate transport of a printable substrate having ink images thereon and to reduce ink offset from the printable substrate.
摘要:
The present invention provides single chain antibody-directed polymeric prodrugs containing multifunctional linkers. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.
摘要:
Various embodiments provide a device having a multi-scale superoleophobic surface and methods for forming and using the device, wherein a particulate composite layer including metal-containing particulates is formed on a textured micron-/sub-micron surface of a semiconductor layer to provide device with multi-scale rough surface.
摘要:
Disclosed are systems biology-based methods for repositioning known pharmaceutical compounds to new indications, through the identification of network-based signatures. In particular, the invention provides new and useful methods for selecting drugs or combinations of drugs (and preferably previously-approved drugs) for use in new therapeutic indications. Also disclosed are methods for identifying anti-breast tumor initiating cell (TIC)-based therapeutics from within populations of target compounds. In illustrative embodiments, the invention provides methods and computer programs for the repositioning of FDA-approved pharmaceutical compounds to new indications using network-based signature analysis coupled with conventional in vitro and in vivo testing of identified drug candidates. The invention also allows identification of drugs or drug combinations for treating unmet medical needs including, for example, “orphan” diseases.
摘要:
A four arm-polyethylene glycol-7-ethyl-10-hydroxycamptothecin conjugate, such as, is disclosed. Methods of making the conjugates and methods of treating mammals using the same are also disclosed.
摘要:
A process for preparing a flexible device having a textured superoleophobic surface comprising providing a flexible substrate; disposing a silicon layer on the flexible substrate; using photolithography to create a textured pattern in the silicon layer on the substrate wherein the textured pattern comprises an array of pillars; and chemically modifying the textured surface by disposing a conformal oleophobic coating thereon; to provide a flexible device having a superoleophobic surface and, in embodiments, to provide a flexible device having a surface that is both superoleophobic and superhydrophobic.