利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

19 条记录 (耗时 0.015 秒)

    Derivatives of cholest-4-en-3-one oxime, pharmaceutical compositions containing them and preparation method
    13.
    发明授权
    Derivatives of cholest-4-en-3-one oxime, pharmaceutical compositions containing them and preparation method 有权
    胆甾-4-烯-3-酮肟的衍生物，含有它们的药物组合物及其制备方法

    公开(公告)号：US08481515B2

    公开(公告)日：2013-07-09

    申请号：US12158640

    申请日：2006-12-15

    申请人： Cyrille Drouot ,  Delphine Maux

    发明人： Cyrille Drouot ,  Delphine Maux

    IPC分类号： A61K31/575 ,  C07J41/00

    CPC分类号： C07J41/0016

    摘要： The object of the invention is the use as a drug of a compound fitting formula I wherein X represents an oxygen atom or a ═N—OH group and R represents a group selected from or one of its esters and/or of its addition salts with pharmaceutically acceptable acids, particularly as a cytoprotective drug, preferentially a cardioprotective and/or neuroprotective drug, the compounds of formula I wherein R is R2, R3, R4, R5 or R6 as novel compounds as well as their preparation method and use.

    摘要翻译： 本发明的目的是用作化合物配方I的药物的用途，其中X表示氧原子或= N-OH基团，R表示选自其酯和/或其加成盐中的一种或其加成盐的基团， 药学上可接受的酸，特别是细胞保护性药物，优选心脏保护和/或神经保护药物，式I化合物，其中R是R2，R3，R4，R5或R6作为新化合物及其制备方法和用途。

    NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICINE
    14.
    发明申请
    NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICINE 失效
    新化学化合物及其作为医药的用途

    公开(公告)号：US20090203747A1

    公开(公告)日：2009-08-13

    申请号：US11994354

    申请日：2006-06-29

    申请人： Corinne Chaimbault ,  Cyrille Drouot ,  Laure Jamot ,  Rebecca Pruss ,  Celine Simon

    发明人： Corinne Chaimbault ,  Cyrille Drouot ,  Laure Jamot ,  Rebecca Pruss ,  Celine Simon

    IPC分类号： A61K31/426 ,  C07D277/38 ,  C07D401/02 ,  C07C337/08 ,  A61K31/437 ,  A61P25/00

    CPC分类号： C07D277/50

    摘要： The present invention relates to the field of pharmacy, especially the treatment of neurodegenerative diseases. The invention specifically relates to a family of chemical compounds for which a neuroprotective activity has been demonstrated.Given that certain members of said family are novel compounds which have never been described, the invention relates to said novel products, the synthesis method thereof and certain novel intermediate synthesis products.The present invention further relates to compositions comprising the compounds of said family, and the use of said compounds as medicaments, especially for the preparation of a medicament for the treatment of neurodegenerative diseases.

    摘要翻译： 本发明涉及药学领域，特别是治疗神经变性疾病。 本发明具体涉及已经证明了神经保护活性的化合物族。 鉴于所述家族的某些成员是未经描述的新化合物，本发明涉及所述新产品，其合成方法和某些新型中间体合成产品。 本发明还涉及包含所述家族化合物的组合物和所述化合物作为药物的用途，特别是用于制备用于治疗神经变性疾病的药物。

    NOVEL DERIVATIVES OF CHOLEST-4-EN-3-ONE OXIME, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PREPARATION METHOD
    16.
    发明申请
    NOVEL DERIVATIVES OF CHOLEST-4-EN-3-ONE OXIME, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PREPARATION METHOD 有权
    美国4-EN-3-ONE OXIME的新型衍生物，含有它们的药物组合物和制备方法

    公开(公告)号：US20090203662A1

    公开(公告)日：2009-08-13

    申请号：US12158640

    申请日：2006-12-15

    申请人： Cyrille Drouot ,  Delphine Maux

    发明人： Cyrille Drouot ,  Delphine Maux

    IPC分类号： A61K31/575 ,  C07J41/00

    CPC分类号： C07J41/0016

    摘要： The object of the invention is the use as a drug of a compound fitting formula I wherein X represents an oxygen atom or a ═N—OH group and R represents a group selected from or one of its esters and/or of its addition salts with pharmaceutically acceptable acids, particularly as a cytoprotective drug, preferentially a cardioprotective and/or neuroprotective drug, the compounds of formula I wherein R is R2, R3, R4, R5 or R6 as novel compounds as well as their preparation method and use.

    摘要翻译： 本发明的目的是用作化合物配方I的药物的用途，其中X代表氧原子或-N-OH基团，R代表选自其酯和/或其加成盐之一或/ 药学上可接受的酸，特别是细胞保护性药物，优选心脏保护和/或神经保护药物，式I化合物，其中R是R2，R3，R4，R5或R6作为新化合物及其制备方法和用途。

    NOVEL COMPOSITION BASED ON CHOLEST-4-EN-3-ONE OXIME
    19.
    发明申请
    NOVEL COMPOSITION BASED ON CHOLEST-4-EN-3-ONE OXIME 审中-公开
    基于CHOLEST-4-EN-3-ONE OXIME的新型组合物

    公开(公告)号：US20100099652A1

    公开(公告)日：2010-04-22

    申请号：US12593441

    申请日：2008-03-26

    申请人： Cyrille Drouot ,  Patrick Berna

    发明人： Cyrille Drouot ,  Patrick Berna

    IPC分类号： A61K31/56

    CPC分类号： A61K9/08 ,  A61K9/4875

    摘要： A subject of the invention is a novel composition, particularly a pharmaceutical composition comprising cholest-4-en-3-one oxime and an oil chosen from sesame oil, olive oil, soya oil, cotton oil, or a mixture of commercial medium-chain triglycerides (ESTASAN®, MYGLIOL®), or a mixture of these oils, preferably sesame oil, olive oil or soya oil, even more preferably sesame oil.

    摘要翻译： 本发明的主题是一种新型组合物，特别是包含胆甾醇-4-烯-3-酮肟和选自芝麻油，橄榄油，大豆油，棉花油或商业中链的混合物的油的药物组合物 甘油三酯（ESTASAN？，MYGLIOL？），或这些油的混合物，优选芝麻油，橄榄油或大豆油，甚至更优选芝麻油。