-
11.发明申请AMINO- OR AMMONIUM-CONTAINING SULFONIC ACID, PHOSPHONIC ACID AND CARBOXYLIC ACID DERIVATIVES AND THEIR MEDICAL USE 有权氨基酸或含氨酸的硫酸，磷酸和羧酸衍生物及其医疗用途公开(公告)号：US20160016981A1
公开(公告)日：2016-01-21
申请号：US14403167
申请日：2012-05-25
申请人： Georg Schlechtingen , Hans-Joachim Knölker , Tim Friedrichson , Gary Jennings , Tobias Braxmeier
发明人： Georg Schlechtingen , Hans-Joachim Knölker , Tim Friedrichson , Gary Jennings , Tobias Braxmeier
IPC分类号： C07F9/40 , C07D211/62 , C07C229/12 , C07D211/46 , C07C309/14 , C07F9/38
CPC分类号： C07F9/4006 , A61K31/205 , A61K31/4425 , A61K31/662 , C07C229/12 , C07C309/14 , C07D211/06 , C07D211/46 , C07D211/60 , C07D211/62 , C07D295/037 , C07F9/3808
摘要： The present invention relates to amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder.
摘要翻译： 本发明涉及含氨基或铵的磺酸，膦酸和羧酸衍生物，特别是式1，2，3，4，5或6的化合物及其医疗用途，包括它们在治疗中的用途 ，预防或改善炎症，自身免疫和/或过敏性疾病。
-
公开(公告)号：US08394785B2
公开(公告)日：2013-03-12
申请号：US13176979
申请日：2011-07-06
IPC分类号： A61K31/661 , A61K31/675
CPC分类号： A61K31/14
摘要： The present invention relates to a method for the treatment and/or amelioration of urticaria, the method comprising the administration of a pharmaceutically active dose of a compound of formula I to a subject in need of such a treatment and/or amelioration.
摘要翻译： 本发明涉及治疗和/或改善荨麻疹的方法，所述方法包括向需要这种治疗和/或改善的受试者施用药学活性剂量的式I化合物。
-
公开(公告)号：US07998945B2
公开(公告)日：2011-08-16
申请号：US12158615
申请日：2006-12-20
IPC分类号： A61K31/452 , A61K31/661
CPC分类号： A61K31/14
摘要： The present invention relates to a method for the treatment and/or amelioration of atopic dermatitis, the method including the administration of a pharmaceutically active dose of a compound selected from miltefosine, edelfosine, perifosine and ilmofosine to a subject in need of such a treatment and/or amelioration.
摘要翻译： 本发明涉及治疗和/或改善特应性皮炎的方法，所述方法包括向需要这种治疗的受试者施用药物活性剂量的选自米替福德，edelfosine，perifosine和ilmofosine的化合物，以及 /或改善。
-
14.发明申请公开(公告)号：US20090018105A1
公开(公告)日：2009-01-15
申请号：US12158615
申请日：2006-12-20
IPC分类号： A61K31/685 , A61P37/06
CPC分类号： A61K31/14
摘要： The present invention relates of the use of certain inner ionic (zwitter ionic) phospholipids, phosphonolipids and phosphate derivatives for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of an immunological disorder related to mast cell sensitization. Preferred in this context are edelfosine and miltefosine. In a particularly preferred embodiment, the present invention relates to the use of miltefosine for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of allergic diseases, in particular acute hyperallergic diseases, like asthma.
摘要翻译： 本发明涉及某些内离子（两性离子）磷脂，磷脂酰脂和磷酸酯衍生物在制备用于治疗，预防和/或改善与肥大细胞增感相关的免疫学障碍的药物组合物中的用途。 在本文中优选的是edelfosine和miltefosine。 在特别优选的实施方案中，本发明涉及米替福星在制备用于治疗，预防和/或改善过敏性疾病，特别是急性高过敏性疾病如哮喘的药物组合物中的用途。
-
15.再颁专利公开(公告)号：USRE38434E1
公开(公告)日：2004-02-24
申请号：US09974496
申请日：2001-10-10
申请人： Gary Jennings
发明人： Gary Jennings
IPC分类号： G05D700
CPC分类号： B01D45/02 , E21B43/34 , F04C19/00 , F04C19/004 , Y10T137/0396 , Y10T137/3003 , Y10T137/85978
摘要： A gas compressor system draws and compresses gas from a well, wherein the gas has entrained liquid and vapor. The apparatus has a scrubber vessel for receiving the gas and separating at least a portion of the liquid. A storage vessel integral with the scrubber stores seal liquid. The seal liquid is injected into the gas before a single stage liquid ring pump which uses the seal liquid to compress the gas. The compressed gas along with entrained seal liquid is routed to a separator vessel having a coalescing filter. The entrained seal liquid is separated from the gas and routed back to the storage vessel.
-
16.发明授权公开(公告)号：US06227222B1
公开(公告)日：2001-05-08
申请号：US09477934
申请日：2000-01-05
申请人： Gary Jennings
发明人： Gary Jennings
IPC分类号： G05D700
CPC分类号： B01D45/02 , E21B43/34 , F04C19/00 , F04C19/004 , Y10T137/0396 , Y10T137/3003 , Y10T137/85978
摘要： A gas compressor system draws and compresses gas from a well, wherein the gas has entrained liquid and vapor. The apparatus has a scrubber vessel for receiving the gas and separating at least a portion of the liquid. A storage vessel integral with the scrubber stores seal liquid. The seal liquid is injected into the gas before a single stage liquid ring pump which uses the seal liquid to compress the gas. The compressed gas along with entrained seal liquid is routed to a separator vessel having a coalescing filter. The entrained seal liquid is separated from the gas and routed back to the storage vessel.
摘要翻译： 气体压缩机系统从井抽出和压缩气体，其中气体夹带有液体和蒸气。 该装置具有用于接收气体并分离至少一部分液体的洗涤器容器。 与洗涤器集成的储存容器存储密封液体。 在使用密封液压缩气体的单级液环泵之前，将密封液注入气体中。 将压缩气体与夹带的密封液一起送至具有聚结过滤器的分离容器。 夹带的密封液体与气体分离并返回储存容器。
-
公开(公告)号：US07396287B2
公开(公告)日：2008-07-08
申请号：US11541943
申请日：2006-10-02
申请人： Gary Jennings , Peter C Probert
发明人： Gary Jennings , Peter C Probert
IPC分类号： B21K1/58
CPC分类号： F16B19/1054
摘要： A blind rivet formed with a tubular shell, and a mandrel extending through the shell. The shell has an outwardly extending flange at one end forming a rivet head, and having a first set of radial indentations arranged around the periphery of the shell at a first distance from the rivet head, and a second set of radial indentations arranged around the periphery of the shell at a second distance from the rivet head. Each of the radial indentations are formed by crimping them in the rivet shell after the shell has been positioned around the mandrel with the end of the shell remote from the rivet head defining the blind end of the rivet shell. Lastly, the mandrel having a head formed at one end to abut against the blind end of the shell, and the stem extending from the head having a point of weakness part way along the length thereof disposed within the shell.
摘要翻译： 形成有管状壳体的盲铆钉和延伸穿过壳体的心轴。 壳体在一端具有向外延伸的凸缘，形成铆钉头，并且具有第一组径向压痕，该第一组径向压痕以距离铆钉头第一距离的方式围绕壳体的周边设置;以及第二组径向压痕， 的距离铆钉头的第二距离。 每个径向凹口通过在壳体围绕心轴定位之后将它们压接在铆钉壳体中而形成，其中壳体的端部远离限定铆钉壳的盲端的铆钉头。 最后，心轴具有在一端形成的头部，以抵靠壳体的盲端，并且杆从头部沿着其设置在壳体内的长度方向部分延伸。
-
公开(公告)号：US20070147971A1
公开(公告)日：2007-06-28
申请号：US11541943
申请日：2006-10-02
申请人： Gary Jennings , Peter Probert
发明人： Gary Jennings , Peter Probert
CPC分类号： F16B19/1054
摘要： A blind rivet formed with a tubular shell, and a mandrel extending through the shell. The shell has an outwardly extending flange at one end forming a rivet head, and having a first set of radial indentations arranged around the periphery of the shell at a first distance from the rivet head, and a second set of radial indentations arranged around the periphery of the shell at a second distance from the rivet head. Each of the radial indentations are formed by crimping them in the rivet shell after the shell has been positioned around the mandrel with the end of the shell remote from the rivet head defining the blind end of the rivet shell. Lastly, the mandrel having a head formed at one end to abut against the blind end of the shell, and the stem extending from the head having a point of weakness part way along the length thereof disposed within the shell.
摘要翻译： 形成有管状壳体的盲铆钉和延伸穿过壳体的心轴。 壳体在一端具有向外延伸的凸缘，形成铆钉头，并且具有第一组径向压痕，该第一组径向压痕以距离铆钉头第一距离的方式围绕壳体的周边设置;以及第二组径向压痕， 的距离铆钉头的第二距离。 每个径向凹口通过在壳体围绕心轴定位之后将它们压接在铆钉壳体中而形成，其中壳体的端部远离限定铆钉壳的盲端的铆钉头。 最后，心轴具有在一端形成的头部，以抵靠壳体的盲端，并且杆从头部沿着其设置在壳体内的长度方向部分延伸。
-
公开(公告)号：US07198283B2
公开(公告)日：2007-04-03
申请号：US10794291
申请日：2004-03-05
申请人： Bryan Van Den Bosch , Roy Potts , John Mariciak , Bryan Jennings , Gary Jennings
发明人： Bryan Van Den Bosch , Roy Potts , John Mariciak , Bryan Jennings , Gary Jennings
IPC分类号： B60D1/00
CPC分类号： B60D1/00
摘要： A cart assembly comprises an undercarriage supporting a cart frame, the undercarriage having one end and a connecting portion extending from cart frame and/or the undercarriage for connecting the cart assembly with an adjacent article, the cart frame including a handle portion disposed at an elevation for manipulation by a human operator in an upright standing position to steer or otherwise control the cart assembly, and an actuating member mounted on the handle portion for actuating the connecting portion between a first connecting position and a second disconnecting position.
摘要翻译： 车辆组件包括支撑车架的起落架，底架具有一端和从车架和/或底架延伸的连接部分，用于将车辆组件与相邻物品连接，车架包括设置在立面上的把手部分 用于由操作者在直立站立位置进行操纵以转向或以其他方式控制推车组件;以及致动构件，其安装在手柄部分上，用于致动第一连接位置和第二断开位置之间的连接部分。
-
公开(公告)号：US20110212122A1
公开(公告)日：2011-09-01
申请号：US12809261
申请日：2008-12-22
申请人： Martin Bachmann , Gary Jennings , Till Röhn
发明人： Martin Bachmann , Gary Jennings , Till Röhn
CPC分类号： C07K16/22 , A61K2039/5258 , A61K2039/6075 , A61K2039/62 , C07K14/48 , C07K2317/73 , C12N7/00 , C12N2795/00023 , C12N2795/18123
摘要： The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) linked to at least one antigen, wherein said antigen is NGF antigen. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular, for the treatment of pain. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses.
摘要翻译： 本发明涉及医药，公共卫生，免疫学，分子生物学和病毒学领域。 本发明提供包含与至少一种抗原连接的病毒样颗粒（VLP）的组合物，其中所述抗原是NGF抗原。 本发明还提供了一种制备该组合物的方法。 本发明的组合物可用于疫苗的生产，特别是用于治疗疼痛。 此外，本发明的组合物诱导有效的免疫应答，特别是抗体应答。
-
-
-
-
-
-
-
-
-
搜索结果
27 条记录 (耗时 0.045 秒)
