公开(公告)号：US20180094247A1

公开(公告)日：2018-04-05

申请号：US15820766

申请日：2017-11-22

Applicant: Wisconsin Alumni Research Foundation

Inventor： Mark R. Etzel

IPC: C12N7/00 ,  A61L2/00 ,  B01D61/14 ,  B01D67/00 ,  B01J20/26 ,  B01J20/28 ,  B01J20/32

CPC classification number: C12N7/00 ,  A61L2/0017 ,  B01D61/147 ,  B01D67/0093 ,  B01D2325/12 ,  B01D2325/16 ,  B01J20/261 ,  B01J20/262 ,  B01J20/28033 ,  B01J20/2808 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3253 ,  B01J20/3255 ,  B01J20/3285 ,  C12N2795/14251

Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.