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公开(公告)号：US20220295809A1
公开(公告)日：2022-09-22
申请号：US17832858
申请日：2022-06-06
Applicant: Wisconsin Alumni Research Foundation
Inventor： Mark R. Etzel , Abhiram Arunkumar , Shantanu Agarwal
Abstract: The present invention concerns a method for concentrating dairy proteins. The method includes producing and using negatively-charged ultrafiltration membranes to achieve high hydraulic permeability with low sieving coefficients. The method thus yields good protein concentration at a fast rate.
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公开(公告)号：US10604742B2
公开(公告)日：2020-03-31
申请号：US16393121
申请日：2019-04-24
Applicant: Wisconsin Alumni Research Foundation
Inventor： Mark R. Etzel
Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
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公开(公告)号：US20160264942A1
公开(公告)日：2016-09-15
申请号：US15163050
申请日：2016-05-24
Applicant: Wisconsin Alumni Research Foundation
Inventor： Mark R. Etzel
IPC: C12N7/00
CPC classification number: C12N7/00 , A61L2/0017 , B01D61/147 , B01D67/0093 , B01D2325/12 , B01D2325/16 , B01J20/261 , B01J20/262 , B01J20/28033 , B01J20/2808 , B01J20/321 , B01J20/3212 , B01J20/3219 , B01J20/3248 , B01J20/3251 , B01J20/3253 , B01J20/3255 , B01J20/3285 , C12N2795/14251
Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
Abstract translation: 描述了一次性的病毒捕获膜以及从溶液中除去病毒的相应方法。 膜包括一次性的微孔过滤膜和固定在膜上的配体。 配体不可逆地和选择性地结合病毒。 配体还具有足够高的pKa以通过静电电荷排斥来排斥抗体。
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4.发明申请GLYCOMACROPEPTIDE MEDICAL FOODS FOR NUTRITIONAL MANAGEMENT OF PHENYLKETONURIA AND OTHER METABOLIC DISORDERS 审中-公开胰岛素和其他代谢紊乱的营养管理用GLYCOMACROPEPTIDE医疗食品公开(公告)号：US20130196024A1
公开(公告)日：2013-08-01
申请号：US13795125
申请日：2013-03-12
Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
Inventor： Denise M. Ney , Mark R. Etzel
IPC: A23L1/305
CPC classification number: A23L33/17 , A61K38/018 , A61K2300/00
Abstract: Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
Abstract translation: 公开了含有糖原素和附加补充量的精氨酸，亮氨酸和任选的其它氨基酸如酪氨酸的医用食品。 医学食品可用于为具有代谢性疾病如苯丙酮尿症的患者提供完整的蛋白质要求。
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公开(公告)号：US20190249150A1
公开(公告)日：2019-08-15
申请号：US16393121
申请日：2019-04-24
Applicant: Wisconsin Alumni Research Foundation
Inventor： Mark R. Etzel
CPC classification number: C12N7/00 , A61L2/0017 , B01D61/147 , B01D67/0093 , B01D2325/12 , B01D2325/16 , B01J20/261 , B01J20/262 , B01J20/28033 , B01J20/2808 , B01J20/321 , B01J20/3212 , B01J20/3219 , B01J20/3248 , B01J20/3251 , B01J20/3253 , B01J20/3255 , B01J20/3285 , C12N2795/14251
Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
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Patent Agency Ranking
公开(公告)号：US10316296B2
公开(公告)日：2019-06-11
申请号：US15820766
申请日：2017-11-22
Applicant: Wisconsin Alumni Research Foundation
Inventor： Mark R. Etzel
Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
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公开(公告)号：US09856459B2
公开(公告)日：2018-01-02
申请号：US15163050
申请日：2016-05-24
Applicant: Wisconsin Alumni Research Foundation
Inventor： Mark R. Etzel
CPC classification number: C12N7/00 , A61L2/0017 , B01D61/147 , B01D67/0093 , B01D2325/12 , B01D2325/16 , B01J20/261 , B01J20/262 , B01J20/28033 , B01J20/2808 , B01J20/321 , B01J20/3212 , B01J20/3219 , B01J20/3248 , B01J20/3251 , B01J20/3253 , B01J20/3255 , B01J20/3285 , C12N2795/14251
Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.
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8.发明申请GLYCOMACROPEPTIDE MEDICAL FOODS FOR NUTRITIONAL MANAGEMENT OF PHENYLKETONURIA AND OTHER METABOLIC DISORDERS 审中-公开胰岛素和其他代谢紊乱的营养管理用GLYCOMACROPEPTIDE医疗食品公开(公告)号：US20140248414A1
公开(公告)日：2014-09-04
申请号：US14274253
申请日：2014-05-09
Applicant: Wisconsin Alumni Research Foundation
Inventor： Denise M. Ney , Mark R. Etzel
IPC: A23L1/305
CPC classification number: A23L33/17 , A61K38/018 , A61K2300/00
Abstract: Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
Abstract translation: 公开了含有糖原素和附加补充量的精氨酸，亮氨酸和任选的其它氨基酸如酪氨酸的医用食品。 医学食品可用于为具有代谢性疾病如苯丙酮尿症的患者提供完整的蛋白质要求。
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公开(公告)号：US20190254301A1
公开(公告)日：2019-08-22
申请号：US16398908
申请日：2019-04-30
Applicant: Wisconsin Alumni Research Foundation
Inventor： Mark R. Etzel , Abhiram Arunkumar , Shantanu Agarwal
Abstract: The present invention concerns a method for concentrating dairy proteins. The method includes producting and using negatively-charged ultrafiltration membranes to achieve high hydraulic permeability with low sieving coefficients. The method thus yields good protein concentration at a fast rate.
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10.发明授权公开(公告)号：US10258074B2
公开(公告)日：2019-04-16
申请号：US14274253
申请日：2014-05-09
Applicant: Wisconsin Alumni Research Foundation
Inventor： Denise M. Ney , Mark R. Etzel
Abstract: Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
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