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11.发明申请INTRAVASCULAR HEAT EXCHANGE CATHETER WITH MULTIPLE SPACED APART DISCRETE COOLANT LOOPS 审中-公开带多个间隔APART离心冷藏室的血管热交换器公开(公告)号：US20160113813A1
公开(公告)日：2016-04-28
申请号：US14989458
申请日：2016-01-06
Applicant: Zoll Circulation, Inc.
Inventor： Alex L. Lim , Masouneh Mafi , Venkata Vishnu Gurukula
IPC: A61F7/12
CPC classification number: A61F7/12 , A61F7/123 , A61F2007/0054 , A61F2007/0056 , A61F2007/0091 , A61F2007/126
Abstract: A catheter has a series of hollow loops arranged along a tube for carrying working fluid from a heat exchange system to exchange heat with a patient in whom the catheter is advanced. The loops when inflated are transverse to the catheter axis and parallel to each other, and circumscribe a hollow passageway through which blood can flow. Blood also flows around the outer perimeters of the loops.
Abstract translation: 导管具有沿着管布置的一系列中空环，用于承载来自热交换系统的工作流体，以与导管进入的患者进行热交换。 当充气时的环横向于导管轴线并且彼此平行，并且环绕血液可以流过的中空通道。 血液也流过环路的外围。
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公开(公告)号：US09283112B2
公开(公告)日：2016-03-15
申请号：US14509271
申请日：2014-10-08
Applicant: ZOLL CIRCULATION, INC.
Inventor： Alex L. Lim , Venkata Vishnu Gurukula , Jeremy T. Dabrowiak , Richard A. Helkowski
CPC classification number: A61F7/12 , A61F7/0085 , A61F2007/0054 , A61F2007/0056 , A61F2007/0094 , A61F2007/0096 , A61F2007/126 , A61M25/00 , A61M2025/0004 , A61M2205/18 , A61M2205/3368
Abstract: A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.
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公开(公告)号：US20180338858A1
公开(公告)日：2018-11-29
申请号：US16051690
申请日：2018-08-01
Applicant: Zoll Circulation, Inc.
Inventor： Richard A. Helkowski , Jeremy T. Dabrowiak , Venkata Vishnu Gurukula , Alex L. Lim
Abstract: A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.
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公开(公告)号：US20160143773A1
公开(公告)日：2016-05-26
申请号：US15009128
申请日：2016-01-28
Applicant: Zoll Circulation, Inc.
Inventor： Richard A. Helkowski , Jeremy T. Dabrowiak , Alex L. Lim , Venkata Vishnu Gurukula
IPC: A61F7/12
CPC classification number: A61F7/12 , A61F7/123 , A61F2007/0054 , A61F2007/0056 , A61F2007/0096 , A61F2007/126
Abstract: A transatrial intravascular temperature management catheter has a lower heat exchange segment positionable in the inferior vena cava and an upper heat exchange segment positionable in the superior vane cava, with a connecting segment lying between the two and positionable in the right atrium. A temperature sensor on the distal tip of the upper heat exchange segment provides accurate core body temperature signals for feedback purposes since the blood flowing past the sensor has not yet reached the heat exchange segment.
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公开(公告)号：US12127971B2
公开(公告)日：2024-10-29
申请号：US16051690
申请日：2018-08-01
Applicant: Zoll Circulation, Inc.
Inventor： Richard A. Helkowski , Jeremy T. Dabrowiak , Venkata Vishnu Gurukula , Alex L. Lim
CPC classification number: A61F7/12 , A61B2017/00867 , A61F2007/126
Abstract: A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.
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Patent Agency Ranking
公开(公告)号：US09433528B2
公开(公告)日：2016-09-06
申请号：US13675241
申请日：2012-11-13
Applicant: Zoll Circulation, Inc.
Inventor： Alex L. Lim , Masouneh Mafi , Venkata Vishnu Gurukula , Richard A. Helkowski
CPC classification number: A61F7/12 , A61F2007/126
Abstract: An intravascular heat exchange catheter has serpentine-like supply and return conduits circulating working fluid with a heat exchange system to warm or cool a patient in which the catheter is intubated.
Abstract translation: 血管内热交换导管具有蛇形状供应和返回导管，循环工作流体与热交换系统以加热或冷却导管被插管的患者。
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公开(公告)号：US09402764B2
公开(公告)日：2016-08-02
申请号：US13625998
申请日：2012-09-25
Applicant: ZOLL CIRCULATION, INC.
Inventor： Jeremy T. Dabrowiak , Alex L. Lim , Venkata Vishnu Gurukula , Richard A. Helkowski , Masoumeh Mafi
CPC classification number: A61F7/12 , A61F2007/0054 , A61F2007/126
Abstract: A patient temperature control catheter (10) includes working fluid supply (16) and return (18) lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. At least one lumen is defined by plural coils (32) axially spaced from each other. At least a first coil is a large coil that inflates with working fluid to seat against a wall of a blood vessel in which the catheter is positioned, with blood flowing through the coil so as not to block blood flow in the vessel. Alternate centering structures (116) are disclosed.
Abstract translation: 患者温度控制导管（10）包括工作流体供应（16）和返回（18）流明，工作流体通过该流体循环以与导管所位于的患者交换热量。 至少一个管腔由彼此轴向间隔开的多个线圈（32）限定。 至少第一线圈是大的线圈，其使用工作流体进行充气以抵靠导管定位的血管的壁，血液流过线圈，以便不阻止血管中的血液流动。 公开了替代的对中结构（116）。
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公开(公告)号：US20160193077A1
公开(公告)日：2016-07-07
申请号：US15069107
申请日：2016-03-14
Applicant: Zoll Circulation, Inc.
Inventor： Alex L. Lim , Venkata Vishnu Gurukula , Jeremy T. Dabrowiak , Richard A. Helkowski
CPC classification number: A61F7/12 , A61F7/0085 , A61F2007/0054 , A61F2007/0056 , A61F2007/0094 , A61F2007/0096 , A61F2007/126 , A61M25/00 , A61M2025/0004 , A61M2205/18 , A61M2205/3368
Abstract: A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.
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19.发明授权公开(公告)号：US09283110B2
公开(公告)日：2016-03-15
申请号：US13622104
申请日：2012-09-18
Applicant: ZOLL CIRCULATION, INC.
Inventor： Alex L. Lim , Venkata Vishnu Gurukula , Jeremy T. Dabrowiak , Richard A. Helkowski
CPC classification number: A61F7/12 , A61F7/0085 , A61F2007/0054 , A61F2007/0056 , A61F2007/0094 , A61F2007/0096 , A61F2007/126 , A61M25/00 , A61M2025/0004 , A61M2205/18 , A61M2205/3368
Abstract: A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.
Abstract translation: 导管具有内套筒，制冷剂通过该内套筒从制冷剂源流出。 导管还具有围绕内套筒的外套筒，包括其远端。 外套筒装有冷冻的生物相容性物质。 制冷剂通过内套筒的一个或多个壁与生物相容性物质分离，使得制冷剂与内套管和冷冻生物相容性物质由导管定位的患者隔离。 当导管位于患者体内时，制冷剂通过导管循环，以便当热量从患者转移到生物相容性物质时，使生物相容性物质保持冷冻。
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20.发明授权Intravascular heat exchange catheter with multiple spaced apart discrete coolant loops 有权血管内热交换导管具有多个间隔分开的冷却剂回路公开(公告)号：US09241827B2
公开(公告)日：2016-01-26
申请号：US13653648
申请日：2012-10-17
Applicant: Zoll Circulation, Inc.
Inventor： Alex L. Lim , Masouneh Mafi , Venkata Vishnu Gurukula
CPC classification number: A61F7/12 , A61F7/123 , A61F2007/0054 , A61F2007/0056 , A61F2007/0091 , A61F2007/126
Abstract: A catheter has a series of hollow loops arranged along a tube for carrying working fluid from a heat exchange system to exchange heat with a patient in whom the catheter is advanced. The loops when inflated are transverse to the catheter axis and parallel to each other, and circumscribe a hollow passageway through which blood can flow. Blood also flows around the outer perimeters of the loops.
Abstract translation: 导管具有沿着管布置的一系列中空环，用于承载来自热交换系统的工作流体，以与导管进入的患者进行热交换。 当充气时的环横向于导管轴线并且彼此平行，并且环绕血液可以流过的中空通道。 血液也流过环路的外围。
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