Use of polysaccharide derivatives as anti-infective substances
    11.
    发明申请
    Use of polysaccharide derivatives as anti-infective substances 失效
    多糖衍生物作为抗感染物质的使用

    公开(公告)号:US20050054609A1

    公开(公告)日:2005-03-10

    申请号:US10500807

    申请日:2003-01-10

    摘要: The present invention relates to a method of treating infectious diseases, that involves: (a) providing an alpha-glycosidically linked starch polysaccharide derivative; and (b) inhibiting the growth of an infectious disease by administering a composition comprising the alpha-glycosidically linked starch polysaccharide derivative. The alpha-glycosidically linked starch polysaccharide derivative represented by the following general formula I, in which: the alpha-glycosidically linked starch polysaccharide derivative has a degree of quaternary ammonium group substitution of from 0.4 to 2.0; n is 2-4; R1 is selected from the group consisting of C1-4 alkyl, benzyl and benzyl substituted with a member selected from the group consisting of C1-3 alkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano, dialkylamino and hydrogen; R2 and R3 are each independently selected from the group consisting of C1-4 alkyl, benzyl and benzyl substituted with a member selected from the group consisting of C1-3 alkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano and dialkylamino; and X is an anion selected from the group consisting of halide, hydroxide, sulfate, hydrogen sulfate and carboxylate.

    摘要翻译: 本发明涉及一种治疗感染性疾病的方法,其涉及:(a)提供α-糖苷连接的淀粉多糖衍生物; 和(b)通过施用包含α-糖苷连接的淀粉多糖衍生物的组合物来抑制感染性疾病的生长。 由以下通式I表示的α-糖苷连接的淀粉多糖衍生物,其中:α-糖苷连接的淀粉多糖衍生物的季铵基取代度为0.4〜2.0; n为2-4; R1选自C1-4烷基,苄基和被选自C1-3烷基,卤素,烷氧基,氨基甲酰基,烷氧基羰基,氰基,二烷基氨基和氢的成员取代的苄基; R2和R3各自独立地选自C1-4烷基,苄基和被选自C1-3烷基,卤素,烷氧基,氨基甲酰基,烷氧基羰基,氰基和二烷基氨基的成员取代的苄基; X是选自卤化物,氢氧化物,硫酸盐,硫酸氢盐和羧酸盐的阴离子。

    Device For Testing Systems, Functions or Components of a Motor Vehicle Independently of a Test-Bench
    13.
    发明申请
    Device For Testing Systems, Functions or Components of a Motor Vehicle Independently of a Test-Bench 审中-公开
    独立于测试台的汽车测试系统,功能或组件的设备

    公开(公告)号:US20080215207A1

    公开(公告)日:2008-09-04

    申请号:US11816752

    申请日:2006-02-26

    申请人: Thomas Heinze

    发明人: Thomas Heinze

    IPC分类号: G01M13/02 G01M17/007

    CPC分类号: G01M13/025

    摘要: The invention relates to a motor vehicle that is provided with a device for testing the systems, functions or components of the vehicle. According to the invention, the vehicle is jacked-up and is equipped with an actuator or a driver to operate the brakes of the vehicle. The vehicle propulsion can rotate freely against the load of at least one brake of the vehicle and the freely rotating wheel or wheels have no frictional connection to the tread contact area of the vehicle. The brakes and/or the propulsion load can be controlled by actuators having a controller or by the driver in accordance with specific signals of the operating condition of the drive train of the vehicle.

    摘要翻译: 本发明涉及一种具有用于测试车辆的系统,功能或部件的装置的机动车辆。 根据本发明,车辆被夹紧并且配备有致动器或驱动器以操作车辆的制动器。 车辆推进可以相对于车辆的至少一个制动器的负载自由旋转,并且自由旋转的车轮或车轮与车辆的胎面接触区域没有摩擦连接。 制动器和/或推进负载可以由具有控制器的致动器或驾驶员根据车辆的传动系的操作条件的特定信号来控制。

    Method of treating infectious diseases with polysaccharide derivatives
    14.
    发明授权
    Method of treating infectious diseases with polysaccharide derivatives 失效
    用多糖衍生物治疗感染性疾病的方法

    公开(公告)号:US07297687B2

    公开(公告)日:2007-11-20

    申请号:US10500807

    申请日:2003-01-10

    摘要: The present invention relates to a method of treating infectious diseases, that involves: (a) providing an alpha-glycosidically linked starch polysaccharide derivative; and (b) inhibiting the growth of an infectious disease by administering a composition comprising the alpha-glycosidically linked starch polysaccharide derivative. The alpha-glycosidically linked starch polysaccharide derivative represented by the following general formula I, in which: the alpha-glycosidically linked starch polysaccharide derivative has a degree of quaternary ammonium group substitution of from 0.4 to 2.0; n is 2-4; R1 is selected from the group consisting of C1-4 alkyl, benzyl and benzyl substituted with a member selected from the group consisting of C1-3 alkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano, dialkylamino and hydrogen; R2 and R3 are each independently selected from the group consisting of C1-4 alkyl, benzyl and benzyl substituted with a member selected from the group consisting of C1-3 alkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano and dialkylamino; and X is an anion selected from the group consisting of halide, hydroxide, sulfate, hydrogen sulfate and carboxylate.

    摘要翻译: 本发明涉及一种治疗感染性疾病的方法,其涉及:(a)提供α-糖苷连接的淀粉多糖衍生物; 和(b)通过施用包含α-糖苷连接的淀粉多糖衍生物的组合物来抑制感染性疾病的生长。 由以下通式I表示的α-糖苷连接的淀粉多糖衍生物,其中:α-糖苷连接的淀粉多糖衍生物的季铵基取代度为0.4〜2.0; n为2-4; R 1选自C 1-4烷基,苄基和被选自C 1-3烷基的成员取代的苄基, 烷基,卤素,烷氧基,氨基甲酰基,烷氧基羰基,氰基,二烷基氨基和氢; R 2和R 3各自独立地选自C 1-4烷基,苄基和被选自以下的成员取代的苄基: 由C 1-3烷基,卤素,烷氧基,氨基甲酰基,烷氧基羰基,氰基和二烷基氨基组成的组; X是选自卤化物,氢氧化物,硫酸盐,硫酸氢盐和羧酸盐的阴离子。