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    NEURAL INTERFACE SYSTEM
    11.
    发明申请
    NEURAL INTERFACE SYSTEM 有权

    公开(公告)号：US20230009490A1

    公开(公告)日：2023-01-12

    申请号：US17780214

    申请日：2020-11-27

    Applicant: Galvani Bioelectronics Limited

    Inventor： Sebastien Ouchouche ,  Cindy Au ,  Kenneth Douglas Rys ,  Thomas Burge

    IPC: A61N1/05

    Abstract: An implantable neural interface system comprising: at least one electrode; a spine providing a passage for electrical conductors connectable to a pulse generator and the at least one electrode; at least one arm extending from the spine, wherein the electrode is positioned on the arm; and a strain relief feature configured to reduce strain in relative movement of portions of neural interface system to accommodate a curvature in an axis of a target on or in which the neural interface is provided.

    Treatment of Acute Medical Conditions
    14.
    发明申请
    Treatment of Acute Medical Conditions 有权

    公开(公告)号：US20220249840A1

    公开(公告)日：2022-08-11

    申请号：US17619215

    申请日：2020-06-17

    Applicant: Galvani Bioelectronics Limited

    Inventor： Isha Gupta ,  Matteo Donega

    IPC: A61N1/36 ,  A61N1/05

    Abstract: Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging, shock, acute respiratory distress syndrome (ARDS), severe respiratory distress syndrome (SARS), and coronavirus disease 19 (COVID-19).

    Electrode devices for neurostimulation
    15.
    发明授权
    Electrode devices for neurostimulation 有权

    公开(公告)号：US11357976B2

    公开(公告)日：2022-06-14

    申请号：US16634632

    申请日：2018-07-23

    Applicant: GALVANI BIOELECTRONICS LIMITED

    Inventor： Faisal Zaidi ,  Sebastien Ouchouche

    IPC: A61N1/05 ,  A61N1/36

    Abstract: An extravascular neural interface is disclosed including a device containing electrodes for neurostimulation of a vessel. The devices are housed in flexible substrates forming two flaps, an inner flap having a spinal portion for routing leads/conductors into the device for connection to the electrodes and an outer flap that overlaps the inner flap. The inner flap supports and positions the electrodes to be inward facing, i.e., extravascular designs. The electrodes may be circular or elliptical and include a plurality of wings for securing the electrodes within a flap.

    PSEUDO-MONOPOLAR NEURAL INTERFACE SYSTEM
    16.
    发明申请
    PSEUDO-MONOPOLAR NEURAL INTERFACE SYSTEM 有权

    公开(公告)号：US20220176107A1

    公开(公告)日：2022-06-09

    申请号：US17593664

    申请日：2020-03-25

    Applicant: Galvani Bioelectronics Limited

    Inventor： Kenneth Douglas RYS

    IPC: A61N1/05 ,  A61N1/36

    Abstract: A neural interface system, comprises a lead body including a first electrode; a cuff body having a first section and a second section separated by a gap for providing a path of least electrical resistance, a second electrode positioned within the first section; and a junction between the lead body and the cuff body, wherein the gap extends around an axis of the cuff body and comprises a first area proximal to the junction.

    Optimizing neuromodulation stimulation parameters using blood parameter sensing
    17.
    发明授权
    Optimizing neuromodulation stimulation parameters using blood parameter sensing 有权

    公开(公告)号：US11167143B2

    公开(公告)日：2021-11-09

    申请号：US16485673

    申请日：2018-02-12

    Applicant: Galvani Bioelectronics Limited

    Inventor： Brian Marc Pepin ,  Shiv Sabesan

    IPC: A61N1/36 ,  A61N1/05 ,  A61N1/375

    Abstract: This disclosure relates to implantable neuromodulation systems and methods, and in particular to systems and methods for sensing blood-based parameter changes triggered by neural stimulation and subsequently optimizing the stimulation parameters based on feedback from the sensed blood-based parameter changes. Embodiments are directed to a method that includes delivering neural stimulation to a nerve or artery/nerve plexus based on a first set of stimulation parameters, monitoring a response to the neural stimulation that includes monitoring responses of the nerve or artery/nerve plexus and blood-based parameters of the artery, modifying the first set of the stimulation parameters based on the blood-based parameters to create a second set of stimulation parameters, and delivering the neural stimulation based on the second set of the stimulation parameters.

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