公开(公告)号：US5984929A

公开(公告)日：1999-11-16

申请号：US941458

申请日：1997-09-30

申请人： Mehran Bashiri ,  Michael P. Wallace ,  Pete Phong Pham ,  Cong Thach ,  Chad C. Roue ,  Erik T. Engelson

发明人： Mehran Bashiri ,  Michael P. Wallace ,  Pete Phong Pham ,  Cong Thach ,  Chad C. Roue ,  Erik T. Engelson

IPC分类号： A61B17/12 ,  A61F2/01 ,  A61F2/02 ,  A61F2/06 ,  A61F2/84 ,  A61B17/00

CPC分类号： A61F2/95 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12154 ,  A61F2/01 ,  A61B2017/12063 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2002/9505 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0069 ,  A61F2230/0091

摘要： This is an implant for placement in the human body and an assembly for so placing that implant. Most desirably, it is an implant for use in the vasculature of the human body and is used to occlude some space in that vasculature as a portion of a treatment regimen. The implant itself is preferably a component of a deployment device using an electrolytically severable joint. The implant is electrically isolated from the electrolytically severable joint by a highly resistive or insulative layer. Such isolation and minimization of the conductive pathway from the placement apparatus to the body's fluids appears to enhance the susceptibility of the electrolytic joint to quick erosion and detachment of the implant from the deployment media. Although the implant itself is preferably a vaso-occlusive device, it may instead be a stent, a vena cava filter, or other implant which may be installed in this manner.

摘要翻译： 这是用于放置在人体中的植入物和用于使得植入物放置的组件。 最理想的是，它是用于人体脉管系统的植入物，并且用于封闭该脉管系统中的一些空间作为治疗方案的一部分。 植入物本身优选是使用电解可分割接头的展开装置的部件。 植入物通过高电阻或绝缘层与电解可分离的接头电隔离。 从放置装置到身体的流体的导电通路的这种隔离和最小化似乎增强了电解接头对植入物从展开介质的快速侵蚀和分离的敏感性。 虽然植入物本身优选为血管闭塞装置，但它可以是支架，腔静脉过滤器或可以以这种方式安装的其它植入物。

公开(公告)号：US5927345A

公开(公告)日：1999-07-27

申请号：US640342

申请日：1996-04-30

申请人： Gene Samson

发明人： Gene Samson

IPC分类号： A61M25/00 ,  A61M39/08 ,  D03D3/02 ,  F16L11/14 ,  F16L11/02

CPC分类号： F16L11/14 ,  A61M39/08 ,  D03D3/02 ,  A61L2400/16 ,  A61M25/0012

摘要： This is a braided tubular structure made up of a plurality of interwoven fibrous members, preferably ribbons, a majority of which comprise one or more superelastic and (at least) ternary alloys of nickel, titanium, and at least about 1.5% (wt) of one or more alloying members selected from the group consisting of vanadium, chromium, manganese, iron, and cobalt.

摘要翻译： 这是由多个交织的纤维构件构成的编织管状结构，优选带，其大部分包括一种或多种超弹性和（至少）三元镍，至少约1.5％（重量）的 一种或多种选自钒，铬，锰，铁和钴的合金成分。

公开(公告)号：US5925059A

公开(公告)日：1999-07-20

申请号：US361330

申请日：1994-12-21

申请人： Thomas J. Palermo ,  Son Gia

发明人： Thomas J. Palermo ,  Son Gia

IPC分类号： A61B17/12 ,  A61F2/01 ,  A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12145 ,  A61F2/01 ,  A61M25/0905 ,  A61B2017/1205 ,  A61B90/39 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0091

摘要： This invention is a surgical instrument and specifically is a device for delivering embolic coils to a selected site within the vasculature of a human body via use of a catheter. The invention further includes the coils. In particular, the device uses embolic coils having interlocking ends, e.g., clasps or hooks, on the ends of the coils. The coils may further be secured to each other by a control wire within the catheter. Retraction of the optional control wire into the catheter body uncouples the distal coil.

摘要翻译： 本发明是一种手术器械，特别是用于通过使用导管将栓塞线圈递送到人体脉管系统内的选定部位的装置。 本发明还包括线圈。 特别地，该装置在线圈的端部使用具有互锁端的栓塞线圈，例如钩扣或钩。 线圈可以进一步通过导管内的控制线彼此固定。 将可选择的控制线缩回到导管体中使远端线圈脱开。

公开(公告)号：US5891112A

公开(公告)日：1999-04-06

申请号：US484943

申请日：1995-06-07

申请人： Gene Samson

发明人： Gene Samson

IPC分类号： A61M25/00

CPC分类号： A61M25/005 ,  A61M2025/0081 ,  A61M25/0053 ,  A61M25/0054

摘要： This is a section of a catheter used in making a catheter assembly suitable for accessing a tissue target within the body, typically a target which is accessible through the vascular system. The catheter section uses a braided metallic reinforcing member, typically of superelastic alloy ribbon, situated within the catheter body in such a way to create a catheter having an exceptionally thin wall, controlled stiffness, high resistance to kinking, and complete recovery in vivo from kinking situations. The braid may have a single pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink. resistant. The catheter sections may be used alone or in conjunction with other catheter sections either made using the concepts shown herein or made in other ways.

摘要翻译： 这是用于制造导管组件的导管的一部分，该导管组件适合于进入身体内的组织靶，通常是可通过血管系统接近的靶。 导管部分使用位于导管体内的编织金属加强构件，通常为超弹性合金带，以形成具有特别薄壁，受控刚度，抗扭结性和体内完全恢复的扭结的导管 情况 编织物可以具有单个间距，或者可以沿着导管或导管部分的轴线变化。 编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常灵活但高度扭结的导管部分。 耐性 导管部分可以单独使用或与使用本文所示的概念或以其它方式制成的其它导管部分结合使用。

公开(公告)号：US5868754A

公开(公告)日：1999-02-09

申请号：US662322

申请日：1996-06-12

申请人： Marc-Alan Levine ,  Son M. Gia ,  Mehran Bashiri ,  David Kupiecki

发明人： Marc-Alan Levine ,  Son M. Gia ,  Mehran Bashiri ,  David Kupiecki

IPC分类号： A61B17/22 ,  A61F11/00 ,  A61B17/00 ,  A61B17/08

CPC分类号： A61B17/221

摘要： This is a device for capturing and removing bodies or articles from within a vessel, such vessels as may be found in the vascular system or the genital urinary tract. It includes a core wire which has attached at its distal end a plurality of fibers. The core wire may be introduced through a catheter to a selected site and further advanced and "twirled" to engage the offending foreign body. The retriever and its targeted foreign body are then withdrawn using the catheter.

摘要翻译： 这是用于从血管系统或生殖泌尿道中可以发现的容器内捕获和去除体内或体内的物品的装置。 它包括在其远端处附接有多根纤维的芯线。 芯线可以通过导管引入到选定的部位，并且进一步前进和“旋转”以接合有害的异物。 然后使用导管撤回猎犬及其目标异物。

公开(公告)号：US5772609A

公开(公告)日：1998-06-30

申请号：US672637

申请日：1996-06-28

申请人： Kim Nguyen ,  Chi J. Chung ,  Thomas J. Palermo

发明人： Kim Nguyen ,  Chi J. Chung ,  Thomas J. Palermo

IPC分类号： A61M25/00 ,  A61B5/00

CPC分类号： A61M25/09 ,  A61M2025/0046 ,  A61M2025/09091 ,  A61M2025/09133 ,  A61M2025/09175

摘要： This invention is a guidewire for guiding a catheter and is used for accessing a targeted site within a lumen system in a body. The guidewire or guidewire section has a wire core, a distal tip region, a polymeric tie layer, and a lubricious coating. The tie layer is preferably constructed to provide for sections of varying flexibility along the length of the guidewire. Variations of the tie layer provide for axially spaced sections of varying flexibility, radially layers of varying flexibility of both. In a special variation, the tie layer is constructed with at least one section providing increased stiffness distally.

摘要翻译： 本发明是用于引导导管的导丝，并且用于进入体内管腔系统内的目标部位。 导线或导丝部分具有线芯，远端尖端区域，聚合物连接层和光滑涂层。 连接层优选构造成沿着导丝的长度提供具有不同柔性的部分。 连接层的变化提供了具有不同柔性的轴向间隔的部分，两者具有不同柔性的径向层。 在一个特殊的变化中，连接层被构造成具有至少一个向远端提供增加的刚度的部分。

公开(公告)号：US5750206A

公开(公告)日：1998-05-12

申请号：US429599

申请日：1995-04-27

申请人： Robert Hergenrother ,  Uriel Hiram Chee ,  Laurent Schaller

发明人： Robert Hergenrother ,  Uriel Hiram Chee ,  Laurent Schaller

IPC分类号： A61L29/08 ,  A61L33/00 ,  A61M25/09 ,  B32B15/08 ,  C23C16/30 ,  C23C16/50 ,  C08J7/18

CPC分类号： A61M25/09 ,  A61L29/085 ,  A61L33/0029 ,  Y10T428/2942

摘要： This invention relates to a new technique for preparing metal devices such as guidewires for the subsequent attachment of hydrophilic coatings. The invention also relates to guidewires and other devices made according to that method. In one embodiment of the method of this invention, a hydrocarbon residue undercoat is applied to a metal guidewire core by plasma deposition. A photoactive hydrophilic polymer is then deposited on the hydrocarbon residue coating and activated by ultraviolet light. The hydrocarbon residue coating acts as a tie layer between the hydrophilic polymer and the metal guidewire core apparently by providing C--C bonds for the covalent linking of the coating material to the tie layer. The resulting article of this invention is a guidewire having the maneuverability of a metal guidewire and the biocompatibility of a lubricious, hydrophilic polymer.

摘要翻译： 本发明涉及一种用于制备金属装置的新技术，例如用于随后附着亲水涂层的导线。 本发明还涉及根据该方法制造的导线和其它装置。 在本发明方法的一个实施方案中，通过等离子体沉积将烃基底涂层施加到金属导丝芯上。 然后将光活性亲水性聚合物沉积在烃残余物涂层上并通过紫外光激活。 烃残留涂层在亲水性聚合物和金属导丝芯之间起粘结层的作用，显然是通过提供用于涂层材料与粘结层的共价连接的C-C键。 本发明的所得物品是具有金属导丝的机动性和润滑的亲水性聚合物的生物相容性的导丝。

公开(公告)号：US5749849A

公开(公告)日：1998-05-12

申请号：US557075

申请日：1996-08-12

申请人： Erik T. Engelson

发明人： Erik T. Engelson

IPC分类号： A61M25/00 ,  A61M29/02 ,  A61M31/00

CPC分类号： A61M29/02 ,  A61M25/0045 ,  A61M25/0054 ,  A61M2025/0079 ,  A61M2025/1063

摘要： This invention is a single-lumen balloon catheter and assembly having a variable stiffness shaft that allows for greater guidewire trackability and proximal pushability than previous designs. The catheter has an elongate tubular body that is made of inner and outer coaxial tubes, the inner tube being made of proximal and distal sections, the proximal section being stiffer than the distal section and the distal section being stiffer than the outer tube.

摘要翻译： PCT No.PCT / US94 / 05679 Sec。 371日期：1996年8月12日 102（e）日期1996年8月12日PCT 1994年5月20日PCT公布。 公开号WO94 / 27668 日期1994年12月8日本发明是具有可变刚度轴的单腔气囊导管和组件，其允许比以前的设计更大的导丝跟踪性和近端推挤性。 导管具有由内外同轴管制成的细长管状体，内管由近端和远端部分制成，近端部分比远端部分更硬，远端部分比外管更硬。

公开(公告)号：US5700258A

公开(公告)日：1997-12-23

申请号：US540354

申请日：1995-09-29

申请人： Gregory E. Mirigian ,  Nga Thi Van ,  Son M. Gia

发明人： Gregory E. Mirigian ,  Nga Thi Van ,  Son M. Gia

IPC分类号： A61B17/00 ,  A61B17/12

CPC分类号： A61B17/12145 ,  A61B17/12022 ,  A61B17/1215

摘要： A vasoocclusive coil for placement in the vasculature of an animal to form thrombus in a selected site such as an aneurysm or AVM. The device involves a primary coil form having thrombogenic fibers placed on the coil in a specified fashion. The coil will pass through the lumen of a vascular catheter in the primary coil form and evolve into a convoluted or complex secondary form when ejected from the catheter's distal end. The fibers are attached to the coil and cooperate with the coil so that upon ejection from the catheter, the convoluted coil forms a shape in which the central region or secondary coil form center that contains the majority of these fibers.

摘要翻译： 用于放置在动物脉管系统中以在所选位点如动脉瘤或AVM中形成血栓的血管收缩性线圈。 该装置涉及具有以特定方式放置在线圈上的血栓形成纤维的初级线圈形式。 线圈将以原始线圈形式通过血管导管的内腔，并且当从导管的远端喷出时，其演变成卷积或复杂的次级形式。 纤维连接到线圈并与线圈配合，使得当从导管喷射时，卷积的线圈形成中心区域或次级线圈形成中心的形状，其中包含大多数这些纤维。

公开(公告)号：US5683410A

公开(公告)日：1997-11-04

申请号：US428061

申请日：1995-04-27

申请人： Gene Samson

发明人： Gene Samson

IPC分类号： A61F2/958 ,  A61M25/00 ,  A61M29/00

CPC分类号： A61M25/0075 ,  A61M25/10 ,  A61M2025/1063 ,  A61M2025/1093 ,  A61M25/09

摘要： This invention is a single-lumen balloon catheter having a valve seat on the distal end of the catheter, distal of the balloon, which may be operated by a control wire having a valve plug disposed on the wire. The valve seat may be engaged by the valve plug from either direction, depending on the installation of the control wire. In either event, if the valve plug is installed distally of the valve seat in the catheter lumen, the valve is closed by pulling on the control wire (or moving the control wire in a proximal direction) and introducing fluid through the catheter lumen through the balloon. Alternatively, the guidewire, with its integral valve plug, may be introduced from the proximal end of the catheter and may traverse the body of the balloon to engage the valve seat in the distal end of the catheter. Pushing on the control wire will seat the valve, allowing the introduction of fluid through the catheter lumen to inflate the balloon. The latter arrangement allows the control wire to be interchanged with other guidewires a physician may wish to use. The balloon provided for in this invention is of a single length and does not change its axial length as it is inflated.

摘要翻译： PCT No.PCT / US93 / 10638 Sec。 371日期：1995年04月27日 102（e）日期1995年4月27日PCT 1993年11月4日PCT公布。 第WO94 / 11047号公报 日期1994年5月26日本发明是一种单腔气囊导管，其具有在导管的远端上的阀座，该气囊远离球囊，其可由具有设置在线上的阀塞的控制线操作。 取决于控制线的安装，阀座可以由阀塞从任一方向接合。 在任一情况下，如果阀塞被安装在导管内腔中阀座的远端，则通过拉动控制线（或沿近端方向移动控制线）并将流体通过导管内腔引入 气球。 或者，具有其一体式阀塞的导丝线可以从导管的近端导入，并且可以穿过气囊的主体以与导管的远端中的阀座接合。 推动控制线将座阀，允许通过导管腔导入流体以使气囊膨胀。 后一种布置允许控制线与医生可能希望使用的其它导线互换。 在本发明中提供的气囊具有单一长度，并且在膨胀时不改变其轴向长度。