公开(公告)号：US20140088577A1

公开(公告)日：2014-03-27

申请号：US14029283

申请日：2013-09-17

Applicant: OmniGuide, Inc.

Inventor： Charalambos Anastassiou ,  Vladimir Fuflyigin ,  Marc Graham ,  Noam Josephy ,  Thieu L. Le ,  Arnaz Singh Malhi ,  Robert Payne ,  Lori Pressman ,  Jesse Rusk ,  Gil Shapira ,  Max Shurgalin ,  Crystal Simon

IPC: A61B18/20

CPC classification number: A61B34/76 ,  A61B18/201 ,  A61B2018/00339 ,  A61B2018/00434 ,  A61B2018/0044 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00601 ,  A61B2018/00607 ,  A61B2018/00642 ,  A61B2018/2065 ,  A61B2018/2238 ,  A61B2090/034 ,  A61B2090/036 ,  A61B2090/061 ,  A61B2090/064

Abstract: Small diameter tools are provided, and methods of use described, to facilitate less invasive surgical procedures employing laser beams. Such tools include distal tips that enhance the precise placement of optical waveguides, as well as enable cutting and dissecting procedures. A rotary coupler allows precise control of flexible conduits in which waveguides may be disposed. Waveguide tips with conical features protect waveguide ends and allow unobstructed propagation of the laser beam out of the waveguide. A preferentially bending jacket for waveguides may be used to control an orientation of a waveguide disposed therein. Surgical waveguide assemblies may include various combinations of these components.

Abstract translation: 提供了小直径的工具以及所使用的使用方法来促进采用激光束的侵入性较小的外科手术。 这样的工具包括提高光波导精确放置的远端尖端以及切割和解剖程序。 旋转耦合器允许精确控制可布置波导的柔性导管。 具有圆锥形特征的波导尖端保护波导端，并允许激光束从波导中不受阻碍地传播。 可以使用用于波导的优选弯曲护套来控制布置在其中的波导的取向。 手术波导组件可以包括这些组件的各种组合。

公开(公告)号：US08655431B2

公开(公告)日：2014-02-18

申请号：US13149502

申请日：2011-05-31

Applicant: Karen Joos ,  Jin Hui Shen ,  M. Shane Hutson ,  John Kozub

Inventor： Karen Joos ,  Jin Hui Shen ,  M. Shane Hutson ,  John Kozub

IPC: A61B5/06 ,  A61B1/07 ,  A61B18/20

CPC classification number: A61B18/18 ,  A61B3/102 ,  A61B18/14 ,  A61B18/20 ,  A61B18/201 ,  A61B18/22 ,  A61B2090/3735

Abstract: An optical coherence tomography probe and laser combination device configured for real-time z-directional guidance of the incisional depth of a surgical procedure. It can be used alone or placed within the working channel of an endoscope. The device includes an OCT single mode fiber, and a laser fiber or laser hollow waveguide or electrical surgical wire positioned adjacent to the OCT single mode fiber. The single mode fiber is configured to move laterally when activated by an actuator to scan light data reflected from a sample that is positioned in front of a distal end of the device. The light data can be processed to generate a B-scan image. The device can collect data in real-time during lasing, or immediately prior to and following the cutting. The surgical tool, when coupled to a processor, can deactivate when the B-scan image identifies that the incision is within a predefined tolerance.

Abstract translation: 光学相干断层扫描探针和激光组合装置被配置成用于实时z方向引导外科手术切口深度。 它可以单独使用或放置在内窥镜的工作通道内。 该装置包括OCT单模光纤以及邻近OCT单模光纤定位的激光光纤或激光中空波导或电手术线。 单模光纤被配置为在由致动器激活时横向移动以扫描从位于设备的远端前方的样品反射的光数据。 可以处理光数据以生成B扫描图像。 该设备可以在激光期间或切割之前或之后立即采集数据。 当B扫描图像识别出切口在预定义的公差内时，手术工具当耦合到处理器时可以停用。

公开(公告)号：US08554031B2

公开(公告)日：2013-10-08

申请号：US13321965

申请日：2010-06-08

Applicant: Vasily N. Astratov

Inventor： Vasily N. Astratov

IPC: G02B6/00 ,  B01J19/12

CPC classification number: G02B6/12004 ,  A61B18/201 ,  A61B2018/2065 ,  A61B2018/2227 ,  A61B2018/2266 ,  B82Y15/00 ,  B82Y20/00 ,  G02B6/0096 ,  G02B6/02304 ,  G02B6/02328 ,  G02B6/032 ,  G02B6/32 ,  G02B6/4206

Abstract: The present invention provides an optical microprobe device and method for focusing multimodal radiation with wavelength-scale spatial resolution and delivering the focused radiation to a specimen, including: a radiation source; and one or more of a plurality of optically transparent or semitransparent spheres and a plurality of optically transparent or semitransparent cylinders optically coupled to the radiation source; wherein the one or more of the plurality of optically transparent or semitransparent spheres and the plurality of optically transparent or semitransparent cylinders periodically focus radiation optically transmitted from the radiation source such that radiation ultimately transmitted to the specimen has predetermined characteristics. Preferably, the spheres or cylinders are assembled inside one of a hollow waveguide, a hollow-core photonic crystal fiber, a capillary tube, and integrated in a multimode fiber. Alternatively, the spheres or cylinders are assembled on a substrate. Optionally, the optical microprobe device also includes one or more of a waveguide, an optical fiber, a lens, and an optical structure disposed between the radiation source and the spheres or cylinders. Optionally, the spheres or cylinders are made from optically nonlinear or active materials that permit efficient nonlinear frequency generation and low-threshold lasing using the optical microprobe device.

Abstract translation: 本发明提供了一种用于聚焦具有波长尺度空间分辨率的多峰辐射并将聚焦辐射传送到样本的光学微探针装置和方法，包括：辐射源; 以及多个光学透明或半透明球体中的一个或多个光学耦合到所述辐射源的光学透明或半透明圆柱体; 其中所述多个光学透明或半透明球体中的一个或多个以及所述多个光学透明或半透明圆柱体周期性地聚焦从所述辐射源光学透射的辐射，使得最终传播到所述样品的辐射具有预定特性。 优选地，球体或圆柱体组装在中空波导，中空光子晶体光纤，毛细管之一内，并集成在多模光纤中。 或者，球体或圆柱体组装在基底上。 可选地，光学微探针装置还包括布置在辐射源和球体或气缸之间的波导，光纤，透镜和光学结构中的一个或多个。 可选地，球体或圆柱体由光学非线性或活性材料制成，其允许使用光学微探针装置的有效非线性频率产生和低阈值激光。

公开(公告)号：US20130236735A1

公开(公告)日：2013-09-12

申请号：US13811261

申请日：2011-07-26

Applicant: Hendrikus Gerardus Maria De Wit ,  Gerrit Jan Pels

Inventor： Hendrikus Gerardus Maria De Wit ,  Gerrit Jan Pels

IPC: A61B18/20

CPC classification number: A61B18/201 ,  A61B18/22 ,  A61B18/24 ,  A61B2018/00095 ,  A61B2018/2255 ,  G02B23/2492 ,  Y10T428/12361 ,  Y10T428/13 ,  Y10T428/131

Abstract: A component for a laser tool, the component comprising: a tubular body defining an internal channel and an aperture; and a window disposed across the aperture and bonded to the tubular body around the aperture, wherein the window is diamond, and wherein the tubular body comprises a material having a coefficient of linear thermal expansion α of 14×10−6 K−1 or less at 20° C. and a thermal conductivity of 60 Wm−1K−1 or more at 20° C.

Abstract translation: 一种用于激光工具的部件，该部件包括：限定内部通道和孔的管状体; 以及窗口，其布置成横跨所述孔并且围绕所述孔结合到所述管状体，其中所述窗口是金刚石，并且其中所述管状体包括具有14×10 -6 K -1以下的线性热膨胀系数α的材料 在20℃下的热导率为60Wm-1K-1或更高。

公开(公告)号：US20130172865A1

公开(公告)日：2013-07-04

申请号：US13822378

申请日：2011-09-30

Applicant: Seong-Mok Cho ,  Moon Youn Jung ,  Seunghwan Kim

Inventor： Seong-Mok Cho ,  Moon Youn Jung ,  Seunghwan Kim

IPC: G21K5/04 ,  A61B18/20

CPC classification number: G21K5/04 ,  A61B18/201 ,  A61N5/1077 ,  A61N2005/1088 ,  H05H6/00

Abstract: Provided are a target structure used for generating a charged particle beam, a method of manufacturing the same, and a medical appliance using the same. The target structure includes a target layer and a support having a through hole used as a progressing path of a laser beam or a charged particle beam.

Abstract translation: 提供了用于产生带电粒子束的目标结构，其制造方法和使用该粒子束的医疗器具。 目标结构包括目标层和具有用作激光束或带电粒子束的前进路径的通孔的支撑体。

公开(公告)号：US20130041356A1

公开(公告)日：2013-02-14

申请号：US13565041

申请日：2012-08-02

Applicant: Ronald T. Smith ,  Michael Arthur Zica ,  Dustin Jacob Bouch

Inventor： Ronald T. Smith ,  Michael Arthur Zica ,  Dustin Jacob Bouch

IPC: A61B18/20

CPC classification number: A61B18/20 ,  A61B1/00066 ,  A61B1/00096 ,  A61B1/07 ,  A61B1/128 ,  A61B18/201 ,  A61B2018/0091 ,  A61B2018/2277 ,  A61F9/00821 ,  A61F2009/00863

Abstract: In particular embodiments of the present invention, an optical surgical probe includes a handpiece configured to optically couple to a light source and a cannula at a distal end of the handpiece. The probe further includes at least one light guide within the handpiece. The light guide is configured to carry a light beam from the light source to a distal end of the handpiece. The probe also includes a multi-spot generator in the cannula that includes a faceted optical adhesive with a faceted end surface spaced from a distal end of the light guide. The faceted end surface includes at least one facet oblique to a path of the light beam. In some embodiments, the probe also includes a high-conductivity ferrule at the distal end of the light guide. In other embodiments, the cannula is formed from a transparent material.

Abstract translation: 在本发明的特定实施例中，光学手术探针包括被配置为光学耦合到手持件的远端处的光源和套管的手持件。 所述探头还包括所述手持件内的至少一个光导。 光导被配置为将来自光源的光束传送到手持件的远端。 探针还包括插管中的多点发生器，其包括具有与光导的远端间隔开的刻面端面的刻面光学粘合剂。 多面端面包括至少一个倾斜于光束路径的小平面。 在一些实施例中，探针还包括在光导的远端处的高导电性套圈。 在其它实施例中，套管由透明材料形成。

公开(公告)号：US08320725B2

公开(公告)日：2012-11-27

申请号：US13165262

申请日：2011-06-21

Applicant: Burak Temelkuran ,  Charalambos Anastassiou ,  David Torres ,  Gil Shapira ,  Max Shurgalin ,  Gregor Dellemann ,  Ori Weisberg ,  Steven A. Jacobs ,  Tairan Wang ,  Uri Kolodny ,  Jesse Rusk ,  Robert Payne ,  Yoel Fink

Inventor： Burak Temelkuran ,  Charalambos Anastassiou ,  David Torres ,  Gil Shapira ,  Max Shurgalin ,  Gregor Dellemann ,  Ori Weisberg ,  Steven A. Jacobs ,  Tairan Wang ,  Uri Kolodny ,  Jesse Rusk ,  Robert Payne ,  Yoel Fink

IPC: G02B6/032 ,  A61B1/04 ,  A61N5/06

CPC classification number: A61B18/201 ,  A61B18/22 ,  A61B18/24 ,  G02B6/02304 ,  G02B6/02385 ,  G02B6/032 ,  G02B6/42

Abstract: In general, in one aspect, the disclosure features a system that includes a flexible waveguide having a hollow core extending along a waveguide axis and a region surrounding the core, the region being configured to guide radiation from the CO2 laser along the waveguide axis from an input end to an output end of the waveguide. The system also includes a handpiece attached to the waveguide, wherein the handpiece allows an operator to control the orientation of the output end to direct the radiation to a target location of a patient and the handpiece includes a tip extending past the output end that provides a minimum standoff distance between the output end and the target location.

Abstract translation: 通常，在一个方面，本发明的特征在于一种系统，其包括柔性波导，该柔性波导具有沿着波导轴线延伸的中空芯和围绕该芯的区域，该区域被配置为沿着波导轴线从CO 2激光器引导辐射 输入端到波导的输出端。 该系统还包括附接到波导的手持件，其中手持件允许操作者控制输出端的取向以将辐射引导到患者的目标位置，并且手持件包括延伸穿过输出端的尖端， 输出端与目标位置之间的最小间隔距离。

公开(公告)号：US08280212B2

公开(公告)日：2012-10-02

申请号：US11366345

申请日：2006-03-02

Applicant: James Goell ,  Marin Soljacic ,  Steven A. Jacobs ,  Tairan Wang ,  Gokhan Ulu ,  Burak Temelkuran ,  Steven G. Johnson

Inventor： James Goell ,  Marin Soljacic ,  Steven A. Jacobs ,  Tairan Wang ,  Gokhan Ulu ,  Burak Temelkuran ,  Steven G. Johnson

IPC: G02B6/02

CPC classification number: G02B6/02304 ,  A61B1/018 ,  A61B18/201 ,  A61B18/22 ,  A61B2018/2272 ,  A61F9/008 ,  A61F9/00802 ,  A61F9/00821 ,  A61F9/00825 ,  A61F2009/00863 ,  A61F2009/00891 ,  C03B2201/86 ,  C03B2203/12 ,  C03B2203/14 ,  C03B2203/16 ,  C03B2203/18 ,  C03B2203/42 ,  G02B6/023 ,  G02B6/02385 ,  G02B6/03622 ,  G02B6/03638 ,  G02B6/03694 ,  Y02P40/57

Abstract: In general, in a first aspect, the invention features photonic crystal fibers that include a core extending along a waveguide axis, a confinement region extending along the waveguide axis surrounding the core, and a cladding extending along the waveguide axis surrounding the confinement region, wherein the cladding has an asymmetric cross-section.

Abstract translation: 通常，在第一方面，本发明的特征在于光子晶体光纤，其包括沿着波导轴延伸的芯，沿着围绕芯的波导轴延伸的约束区域以及沿着围绕限制区域的波导轴延伸的包层，其中 包层具有不对称的横截面。

公开(公告)号：US20120123399A1

公开(公告)日：2012-05-17

申请号：US13379916

申请日：2010-12-31

Applicant: Andrei V. Belikov ,  Felix I. Feldchtein ,  Gregory B. Altshuler

Inventor： Andrei V. Belikov ,  Felix I. Feldchtein ,  Gregory B. Altshuler

IPC: A61B18/22 ,  G02B1/12 ,  A61B18/20

CPC classification number: A61B18/201 ,  A61B18/20 ,  A61B18/22 ,  A61B18/28 ,  A61B2017/00017 ,  A61B2017/00057 ,  A61B2017/00084 ,  A61B2018/00636 ,  A61B2018/00642 ,  A61C1/0046

Abstract: A surgical device based on the concept of controlling the laser power during laser surgery based on optical and other signals from the tip and the tissue is described. A laser surgical system generally comprises several basic components, such as a laser, a delivery system, a tip and a control system. A tip may be considered as a particular case of a thermo-optical tip (TOT). TOT is an optical and mechanical element which could be used to modify or treat soft and hard tissues, including cutting, coagulation, vaporization, carbonization, and ablation of tissues.

Abstract translation: 描述了基于在激光手术期间基于来自尖端和组织的光学信号和其他信号来控制激光功率的概念的手术装置。 激光手术系统通常包括几个基本部件，例如激光器，输送系统，尖端和控制系统。 尖端可以被认为是热光尖端（TOT）的特定情况。 TOT是一种光学和机械元件，可用于修饰或治疗软组织和硬组织，包括切割，凝固，蒸发，碳化和组织消融。

公开(公告)号：US07991258B2

公开(公告)日：2011-08-02

申请号：US12244586

申请日：2008-10-02

Applicant: Burak Temelkuran ,  Charalambos Anastassiou ,  David Torres ,  Gil Shapira ,  Max Shurgalin ,  Gregor Dellemann ,  Ori Weisberg ,  Steven A. Jacobs ,  Tairan Wang ,  Uri Kolodny ,  Jesse Rusk ,  Robert Payne ,  Yoel Fink

Inventor： Burak Temelkuran ,  Charalambos Anastassiou ,  David Torres ,  Gil Shapira ,  Max Shurgalin ,  Gregor Dellemann ,  Ori Weisberg ,  Steven A. Jacobs ,  Tairan Wang ,  Uri Kolodny ,  Jesse Rusk ,  Robert Payne ,  Yoel Fink

IPC: G02B6/00 ,  A61B1/04 ,  A61N5/06

CPC classification number: A61B18/201 ,  A61B18/22 ,  A61B18/24 ,  G02B6/02304 ,  G02B6/02385 ,  G02B6/032 ,  G02B6/42

Abstract: In general, in one aspect, the disclosure features a system that includes a flexible waveguide having a hollow core extending along a waveguide axis and a region surrounding the core, the region being configured to, guide radiation from the CO2 laser along the waveguide axis from an input end to an output end of the waveguide. The system also includes a handpiece attached to the waveguide, wherein the handpiece allows an operator to control the orientation of the output end to direct the radiation to a target location of a patient and the handpiece includes a tip extending past the output end that provides a minimum standoff distance between the output end and the target location.

Abstract translation: 通常，在一个方面，本发明的特征在于一种系统，其包括柔性波导，该柔性波导具有沿着波导轴线延伸的中空芯和围绕该芯的区域，该区域被配置为沿着波导轴线从CO 2激光器引导辐射 输入端到波导的输出端。 该系统还包括附接到波导的手持件，其中手持件允许操作者控制输出端的取向以将辐射引导到患者的目标位置，并且手持件包括延伸穿过输出端的尖端， 输出端与目标位置之间的最小间隔距离。