公开(公告)号：US20150316717A1

公开(公告)日：2015-11-05

申请号：US14106221

申请日：2013-12-13

申请人： Vasily N. ASTRATOV

发明人： Vasily N. ASTRATOV

IPC分类号： G02B6/032 ,  G02B6/42 ,  G02B1/00 ,  G02B6/32

CPC分类号： G02B6/262 ,  A61B18/22 ,  A61B2018/2227 ,  A61B2018/2266 ,  G02B1/00 ,  G02B1/005 ,  G02B6/02304 ,  G02B6/02328 ,  G02B6/032 ,  G02B6/32 ,  G02B6/42 ,  G02B6/4206

摘要： A focusing microprobe system, comprising: one of a single-mode laser radiation source and a few-mode laser radiation source; a coupler coupled to the laser radiation source; one of a single-mode flexible laser radiation delivery system and a few-mode flexible laser radiation delivery system coupled to the coupler; and one or more focusing microlenses coupled to the flexible laser radiation delivery system and arranged in a focusing tip. The coupler comprises a focusing lens. The flexible laser radiation delivery system comprises one of a hollow-core fiber and a flexible waveguide. Optionally, the one or more focusing microlenses are bonded to seal a hollow internal cavity of the flexible laser radiation delivery system. The one or more focusing microlenses comprise one or more conventional lenses or one or more focusing spheres, hemispheres, or cylinders.

摘要翻译： 一种聚焦微探针系统，包括：单模激光辐射源和少模激光辐射源之一; 耦合到激光辐射源的耦合器; 其中一个单模灵活的激光辐射传输系统和耦合到耦合器的多模灵活的激光辐射传送系统; 以及一个或多个聚焦微透镜，其耦合到柔性激光辐射传递系统并且布置在聚焦末端中。 耦合器包括聚焦透镜。 灵活的激光辐射传送系统包括中空芯纤维和柔性波导之一。 可选地，结合一个或多个聚焦微透镜以密封柔性激光辐射递送系统的中空内腔。 一个或多个聚焦微透镜包括一个或多个常规透镜或一个或多个聚焦球体，半球体或圆柱体。

公开(公告)号：US06438305B1

公开(公告)日：2002-08-20

申请号：US09221809

申请日：1998-12-29

申请人： Kenzo Kataoka ,  Masaki Odaka

发明人： Kenzo Kataoka ,  Masaki Odaka

IPC分类号： G02B602

CPC分类号： B23K26/1476 ,  A61B2018/2227 ,  A61C1/0046 ,  B23K26/14 ,  B23K26/146 ,  G02B6/3814 ,  G02B6/4296

摘要： A laser device includes first and second laser transmitting passages. The first laser transmitting passage in the form of tube has an interior opened at its first and second ends. The second laser transmitting passage has first and second ends. The first end of the second laser transmitting passage is spaced away from but optically connected with the second end of the first laser transmitting passage. This allows that laser transmitted through the first laser transmitting passage is guided into the second laser transmitting passage. Air, on the other hand, is transmitted through the first laser transmitting passage to impinge on the first end of the second laser transmitting passage for cooling.

摘要翻译： 激光装置包括第一和第二激光传输通道。 管形式的第一激光传输通道具有在其第一和第二端处打开的内部。 第二激光传送通道具有第一和第二端。 第二激光传输通道的第一端与第一激光传输通道的第二端间隔开但是与光学连接。 这允许透过第一激光传输通道的激光被引导到第二激光传输通道中。 另一方面，空气通过第一激光传递通道传递到第二激光传输通道的第一端以进行冷却。

公开(公告)号：US5951543A

公开(公告)日：1999-09-14

申请号：US885064

申请日：1997-06-30

申请人： Fritz Brauer

发明人： Fritz Brauer

IPC分类号： A61B17/00 ,  A61B18/20 ,  A61B18/22 ,  A61B19/00 ,  A61B17/36

CPC分类号： A61F11/002 ,  A61B18/201 ,  A61B2017/00247 ,  A61B2017/00787 ,  A61B2018/00392 ,  A61B2018/2227 ,  A61B90/37

摘要： The system and method of delivery of laser radiation comprises a flexible hollow waveguide connectable at a first end to a low power laser source, such as a CO.sub.2 laser, a rigid hollow waveguide having a proximal end and a distal end, a coupler for coupling the second end of the flexible hollow waveguide to the proximal end of the rigid hollow waveguide and a diamond tip partially disposed within and extending from the distal end of the rigid waveguide. The diamond tip has an entrance face for receiving laser radiation and at least one exit face for transmitting laser radiation toward an area of biological tissue. The exit end of the diamond tip may be flat, parallel to the entrance face, curved, to act as a lens providing a focusing function, or beveled, to create one or more blade edges to limit the point(s) of exit of the laser radiation and to provide a cutting edge which may be used in combination with the radiation to simultaneously create and photocoagulate the tissue at an incision.

摘要翻译： 激光辐射传送的系统和方法包括可在第一端连接到低功率激光源的柔性中空波导，例如CO 2激光器，具有近端和远端的刚性中空波导，用于将 柔性空心波导的第二端到刚性中空波导的近端，并且金刚石尖端部分地设置在刚性波导的远端内并且从刚性波导的远端延伸。 金刚石尖端具有用于接收激光辐射的入射面和用于将激光辐射传送到生物组织的区域的至少一个出射面。 金刚石尖端的出口端可以是平的，平行于入射面弯曲，以作为提供聚焦功能或斜面的透镜，以产生一个或多个叶片边缘，以限制出口的出口点 激光辐射并且提供可以与辐射组合使用的切割边缘，以同时在切口处产生并凝固组织。

公开(公告)号：US09684125B2

公开(公告)日：2017-06-20

申请号：US15098103

申请日：2016-04-13

申请人： Coherent, Inc.

发明人： Michael Hertwig ,  Norman Hodgson ,  Dmitri Simanovski

IPC分类号： G02B6/02 ,  G02B6/024 ,  G02B6/27 ,  A61B18/22

CPC分类号： G02B6/02304 ,  A61B2018/2227 ,  G02B6/024 ,  G02B6/2706 ,  G02B6/2766

摘要： Plane-polarized laser-radiation from a laser-source is converted to circularly polarized radiation by a quarter-wave plate. The circularly polarized radiation is input into a hollow-core fiber for transport to a point of use. The transported radiation is converted back to plane-polarized radiation by another quarter-wave plate between the fiber and the point of use.

公开(公告)号：US09411103B2

公开(公告)日：2016-08-09

申请号：US14106221

申请日：2013-12-13

申请人： Vasily N. Astratov

发明人： Vasily N. Astratov

IPC分类号： G02B6/32 ,  A61B18/22 ,  G02B6/26 ,  G02B6/032 ,  G02B6/42 ,  G02B1/00 ,  G02B6/02

CPC分类号： G02B6/262 ,  A61B18/22 ,  A61B2018/2227 ,  A61B2018/2266 ,  G02B1/00 ,  G02B1/005 ,  G02B6/02304 ,  G02B6/02328 ,  G02B6/032 ,  G02B6/32 ,  G02B6/42 ,  G02B6/4206

摘要： A focusing microprobe system, comprising: one of a single-mode laser radiation source and a few-mode laser radiation source; a coupler coupled to the laser radiation source; one of a single-mode flexible laser radiation delivery system and a few-mode flexible laser radiation delivery system coupled to the coupler; and one or more focusing microlenses coupled to the flexible laser radiation delivery system and arranged in a focusing tip. The coupler comprises a focusing lens. The flexible laser radiation delivery system comprises one of a hollow-core fiber and a flexible waveguide. Optionally, the one or more focusing microlenses are bonded to seal a hollow internal cavity of the flexible laser radiation delivery system. The one or more focusing microlenses comprise one or more conventional lenses or one or more focusing spheres, hemispheres, or cylinders.

摘要翻译： 一种聚焦微探针系统，包括：单模激光辐射源和少模激光辐射源之一; 耦合到激光辐射源的耦合器; 其中一个单模灵活的激光辐射传输系统和耦合到耦合器的多模灵活的激光辐射传送系统; 以及一个或多个聚焦微透镜，其耦合到柔性激光辐射传递系统并且布置在聚焦末端中。 耦合器包括聚焦透镜。 灵活的激光辐射传送系统包括中空芯纤维和柔性波导之一。 可选地，结合一个或多个聚焦微透镜以密封柔性激光辐射递送系统的中空内腔。 一个或多个聚焦微透镜包括一个或多个常规透镜或一个或多个聚焦球体，半球体或圆柱体。

公开(公告)号：US08554031B2

公开(公告)日：2013-10-08

申请号：US13321965

申请日：2010-06-08

申请人： Vasily N. Astratov

发明人： Vasily N. Astratov

IPC分类号： G02B6/00 ,  B01J19/12

CPC分类号： G02B6/12004 ,  A61B18/201 ,  A61B2018/2065 ,  A61B2018/2227 ,  A61B2018/2266 ,  B82Y15/00 ,  B82Y20/00 ,  G02B6/0096 ,  G02B6/02304 ,  G02B6/02328 ,  G02B6/032 ,  G02B6/32 ,  G02B6/4206

摘要： The present invention provides an optical microprobe device and method for focusing multimodal radiation with wavelength-scale spatial resolution and delivering the focused radiation to a specimen, including: a radiation source; and one or more of a plurality of optically transparent or semitransparent spheres and a plurality of optically transparent or semitransparent cylinders optically coupled to the radiation source; wherein the one or more of the plurality of optically transparent or semitransparent spheres and the plurality of optically transparent or semitransparent cylinders periodically focus radiation optically transmitted from the radiation source such that radiation ultimately transmitted to the specimen has predetermined characteristics. Preferably, the spheres or cylinders are assembled inside one of a hollow waveguide, a hollow-core photonic crystal fiber, a capillary tube, and integrated in a multimode fiber. Alternatively, the spheres or cylinders are assembled on a substrate. Optionally, the optical microprobe device also includes one or more of a waveguide, an optical fiber, a lens, and an optical structure disposed between the radiation source and the spheres or cylinders. Optionally, the spheres or cylinders are made from optically nonlinear or active materials that permit efficient nonlinear frequency generation and low-threshold lasing using the optical microprobe device.

摘要翻译： 本发明提供了一种用于聚焦具有波长尺度空间分辨率的多峰辐射并将聚焦辐射传送到样本的光学微探针装置和方法，包括：辐射源; 以及多个光学透明或半透明球体中的一个或多个光学耦合到所述辐射源的光学透明或半透明圆柱体; 其中所述多个光学透明或半透明球体中的一个或多个以及所述多个光学透明或半透明圆柱体周期性地聚焦从所述辐射源光学透射的辐射，使得最终传播到所述样品的辐射具有预定特性。 优选地，球体或圆柱体组装在中空波导，中空光子晶体光纤，毛细管之一内，并集成在多模光纤中。 或者，球体或圆柱体组装在基底上。 可选地，光学微探针装置还包括布置在辐射源和球体或气缸之间的波导，光纤，透镜和光学结构中的一个或多个。 可选地，球体或圆柱体由光学非线性或活性材料制成，其允许使用光学微探针装置的有效非线性频率产生和低阈值激光。

公开(公告)号：US20040225283A1

公开(公告)日：2004-11-11

申请号：US10762583

申请日：2004-01-23

发明人： Oded Nahleili

IPC分类号： A61B018/20

CPC分类号： A61B18/148 ,  A61B17/24 ,  A61B18/22 ,  A61B18/26 ,  A61B2018/00982 ,  A61B2018/2227 ,  A61N5/0603

摘要： The present invention provides a method for treatment of hard tissues, such as stones, present in very small a fluid-filled body cavity, such as ducts of the salivary glands, by applying to said hard tissue, or to the proximity of said hard tissue, a laser beam produced by an Er:YAG laser device. The invention further concerns a system for use in this method, and an add-on aperture for converting a standard Er:YAG device used in dentistry to a device suitable for the method of the present invention.

摘要翻译： 本发明提供了一种用于治疗存在于非常小的流体填充体腔（例如唾液腺导管）中的硬组织（例如石头）的方法，通过施加到所述硬组织或靠近所述硬组织 ，由Er：YAG激光装置产生的激光束。 本发明还涉及用于该方法的系统以及用于将用于牙科的标准Er：YAG装置转换成适用于本发明方法的装置的附加孔。

公开(公告)号：US09063299B2

公开(公告)日：2015-06-23

申请号：US13515787

申请日：2010-12-13

申请人： Max Shurgalin ,  Vladimir Fuflyigin ,  Douglas Woodruff ,  Mihai Ibanescu ,  Lori Pressman ,  Charalambos Anastassiou ,  Soura Bhattacharyya ,  Yoel Fink

发明人： Max Shurgalin ,  Vladimir Fuflyigin ,  Douglas Woodruff ,  Mihai Ibanescu ,  Lori Pressman ,  Charalambos Anastassiou ,  Soura Bhattacharyya ,  Yoel Fink

IPC分类号： G02B6/02 ,  G02B6/36 ,  G02B6/10 ,  A61B18/20 ,  A61B18/22 ,  G02B6/032 ,  G02B6/24

CPC分类号： G02B6/3624 ,  A61B18/20 ,  A61B18/201 ,  A61B18/203 ,  A61B18/22 ,  A61B2018/2222 ,  A61B2018/2227 ,  G02B6/023 ,  G02B6/02304 ,  G02B6/032 ,  G02B6/10 ,  G02B6/102 ,  G02B6/241

摘要： An apparatus includes a light source configured to provide radiation at a wavelength and a conduit configured to direct radiation at a wavelength from the light source to a target location of a patient. The conduit includes a first optical waveguide extending along a waveguide axis, the first optical waveguide being a flexible waveguide having a hollow core, the first optical waveguide being configured to guide the radiation at through the core along the waveguide axis; and a second optical waveguide extending along the waveguide axis, the second optical waveguide having a hollow core and being coupled to the first optical waveguide to receive the radiation from the first optical waveguide and to deliver the radiation to the target location. The first optical waveguide is a photonic crystal fiber and the second optical waveguide is not a photonic crystal fiber waveguide.

摘要翻译： 一种装置包括被配置为提供波长的辐射的光源和被配置为将来自光源的波长的辐射引导到患者的目标位置的导管。 所述导管包括沿着波导轴延伸的第一光波导，所述第一光波导是具有中空芯的柔性波导，所述第一光波导被配置为沿着波导轴引导穿过所述芯的辐射; 以及沿着波导轴延伸的第二光波导，所述第二光波导具有中空芯并耦合到所述第一光波导以接收来自所述第一光波导的辐射并将所述辐射传送到所述目标位置。 第一光波导是光子晶体光纤，第二光波导不是光子晶体光纤波导。

公开(公告)号：US08894636B2

公开(公告)日：2014-11-25

申请号：US12720466

申请日：2010-03-09

申请人： Henrick K. Gille ,  Fritz A. Brauer

发明人： Henrick K. Gille ,  Fritz A. Brauer

IPC分类号： A61B17/00 ,  A61B18/04 ,  A61B18/18

CPC分类号： A61B18/22 ,  A61B2018/2227 ,  A61B2018/225 ,  A61B2018/2288

摘要： A Minimally Invasive Surgical Laser Hand-piece (“MISLH”) for use with a probe is described. The MISLH has a MISLH proximal end and MISLH distal end, and the MISLH may include an optical coupler located at the MISLH proximal end, a substantially straight central bore within the MISLH, and an internal beam stop aperture within the central bore adjoined to the optical coupler. The central bore may extend from the optical coupler to the MISLH distal end and the central bore may be configured to accept the insertion of the probe within the central bore at the MISLH distal end. Additionally, the central bore may be configured to accept the insertion of the probe such that the probe is adjoined to the internal beam stop aperture.

摘要翻译： 描述了用于探针的微创手术激光手术（“MISLH”）。 MISLH具有MISLH近端和MISLH远端，MISLH可以包括位于MISLH近端处的光学耦合器，MISLH内的基本上直的中心孔，以及与光学器件相邻的中心孔内的内部光束停止孔 耦合器 中心孔可以从光学耦合器延伸到MISLH远端，并且中心孔可以被配置为接受在MISLH远端处的中心孔内的探针的插入。 另外，中心孔可以被配置为接受探针的插入，使得探针与内部光束阻挡孔邻接。

公开(公告)号：US20130064515A1

公开(公告)日：2013-03-14

申请号：US13515787

申请日：2010-12-13

申请人： Max Shurgalin ,  Vladimir Fuflyigin ,  Douglas Woodruff ,  Mihai Ibanescu ,  Lori Pressman ,  Charalambos Anastassiou ,  Soura Bhattacharyya ,  Yoel Fink

发明人： Max Shurgalin ,  Vladimir Fuflyigin ,  Douglas Woodruff ,  Mihai Ibanescu ,  Lori Pressman ,  Charalambos Anastassiou ,  Soura Bhattacharyya ,  Yoel Fink

IPC分类号： G02B6/032

CPC分类号： G02B6/3624 ,  A61B18/20 ,  A61B18/201 ,  A61B18/203 ,  A61B18/22 ,  A61B2018/2222 ,  A61B2018/2227 ,  G02B6/023 ,  G02B6/02304 ,  G02B6/032 ,  G02B6/10 ,  G02B6/102 ,  G02B6/241

摘要： An apparatus includes a light source configured to provide radiation at a wavelength and a conduit configured to direct radiation at a wavelength from the light source to a target location of a patient. The conduit includes a first optical waveguide extending along a waveguide axis, the first optical waveguide being a flexible waveguide having a hollow core, the first optical waveguide being configured to guide the radiation at through the core along the waveguide axis; and a second optical waveguide extending along the waveguide axis, the second optical waveguide having a hollow core and being coupled to the first optical waveguide to receive the radiation from the first optical waveguide and to deliver the radiation to the target location. The first optical waveguide is a photonic crystal fiber and the second optical waveguide is not a photonic crystal fiber waveguide.

摘要翻译： 一种装置包括被配置为提供波长的辐射的光源和被配置为将来自光源的波长的辐射引导到患者的目标位置的导管。 所述导管包括沿着波导轴延伸的第一光波导，所述第一光波导是具有中空芯的柔性波导，所述第一光波导被配置为沿着波导轴引导穿过所述芯的辐射; 以及沿着波导轴延伸的第二光波导，所述第二光波导具有中空芯并耦合到所述第一光波导以接收来自所述第一光波导的辐射并将所述辐射传送到所述目标位置。 第一光波导是光子晶体光纤，第二光波导不是光子晶体光纤波导。