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201.发明公开公开(公告)号：US20230285184A1
公开(公告)日：2023-09-14
申请号：US18020818
申请日：2021-05-17
Inventor： Jae Young MIN , Mee Ran KIM
Abstract: Proposed are a method for producing a patient-customized pessary using a 3D printer and a patient-customized pessary produced thereby and, more specifically, a method for producing a patient-customized pessary using a 3D printer, for forming a pessary so as to correspond to the shape of a patient's vagina, and a patient-customized pessary produced thereby. The method for producing a patient-customized pessary using a 3D printer, comprises a) deriving the shape of a patient's vagina; b) 3D-modeling the shape of a pessary corresponding to the derived shape of the patient's vagina; and c) producing the pessary in the 3D-modeled shape by means of a 3D printer.
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公开(公告)号：US20230248263A1
公开(公告)日：2023-08-10
申请号：US18146848
申请日：2022-12-27
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor： Hyun Gi KIM , Jang Hoon LEE
Abstract: Provided are a method, apparatus and system for prediction of a neonatal brain development prognosis. The computing device includes a memory; and at least one processor performing communication with the memory, wherein the processor is configured to extract cerebral blood flow (CBF) and brain tissue relaxation times T1 and T2 from the input magnetic resonance imaging (MRI) of a subject newborn; generate brain neurodevelopment prediction data of the subject newborn using a pregenerated brain neurodevelopment prediction model; and control the output of the generated brain neurodevelopment prediction data of the subject newborn.
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公开(公告)号：US20230174950A1
公开(公告)日：2023-06-08
申请号：US17995114
申请日：2020-11-24
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
Inventor： Yong Kyun KIM , Dong-Woo CHO , Sun Ah NAM , Jin Won KIM , Jae Yeon LEE , Jae Yun KIM
CPC classification number: C12N5/0697 , A61K35/22 , C12N5/0686 , C12N2506/45 , C12N2513/00 , C12N2533/54 , C12N2533/90
Abstract: The present invention relates to a kidney organoid having a nephron-like structure and a production method therefor. A kidney organoid culture system using kidney dECM hydrogels according to the present invention induced the vascularization of the kidney organoid and the expression of podocytes, tubular transporters, and cilium genes, and has an effect of forming a more mature nephron-like structure. Therefore, the kidney organoid produced by the method of the present invention is an option for treating nephron loss through transplantation into humans, and is expected to be utilized as a kidney on a chip, which is an in vitro kidney model.
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公开(公告)号：US20230039451A1
公开(公告)日：2023-02-09
申请号：US17792271
申请日：2021-01-07
Inventor： Sang Hwa LEE
Abstract: A dental medical record device and a dental medical record method, in which: an image, such as a panoramic photo, a scan image, and a camera image of a patient's oral cavity, is received via artificial intelligence, and charting is performed using the artificial intelligence; and medical records for a treatment area can be read in association with a chart by clicking the treatment area in the image.
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公开(公告)号：US20230008391A1
公开(公告)日：2023-01-12
申请号：US17781842
申请日：2020-10-08
Inventor： Young Nam KANG , Tae Geon OH , Yun Ji SEOL , Na Young AN , Jae Hyeon LEE , Chul Seung KAY , Jin Sol SHIN , Jin Ho HWANG , Hun Joo SHIN , Myung Ho KIM , Hong Seok JANG
IPC: A61N5/10
Abstract: A lung phantom unit for radiotherapy according to an embodiment of the present disclosure may arrange, at a location not affected by a magnetic field, a phantom driving cylinder and a driving device which may move a lung mimic and a tumor mimic in a lung simulation block. The lung phantom unit may be used for general purpose even as a phantom for MRI-based and CT image-based radiotherapy. Since lung and tumor motions are implemented by air injection, it may be possible to precisely measure the motion and volume change of a lung according to subtle changes in air pressure so that customized radiotherapy suitable for a patient having various breathing patterns is possible.
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Patent Agency Ranking
公开(公告)号：US20220409698A1
公开(公告)日：2022-12-29
申请号：US17776835
申请日：2019-11-15
Inventor： Seok-Jung KIM , Mi-La CHO , Hyun-Sik NA , Seon-Yeong LEE , Si-Yeong CHOI , Ji-Ye KWUAN , Keun-Hyung CHO , Goo-Young KIM , Seon-Ae KIM , Eeu-Jeong GO , Jeong-Won CHOI , Jin-Ah BAEK
Abstract: The present invention relates to a composition which is for preventing or treating bone diseases and includes CCR2 as an active ingredient. It was confirmed that a C—C chemokine receptor type 2 (CCR2) protein, a polynucleotide encoding the CCR2 protein, or a mesenchymal stem cell transduced with the CCR2 according to the present invention neutralize bone disease factor MCP-1, thereby reducing the collagen epitope (CTX-II) and collagen metabolism factors (MMP1 and MMP3) relating to collagen absorption in the body. In addition, it was confirmed that the expression of the SOX9 gene and anti-inflammatory cytokines (TGF-β and IL-10) related to cartilage differentiation was significantly increased. Thus, the present invention has excellent regenerative ability against osteoarthritis and excellent pain suppression and alleviation effects, and thus can be effectively used for preventing or treating bone diseases such as osteoarthritis.
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公开(公告)号：US11510772B2
公开(公告)日：2022-11-29
申请号：US16481262
申请日：2018-01-26
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , UNIVERSITY-INDUSTRY FOUNDATION, YONSEI UNIVERSITY , RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY
Inventor： U-Syn Ha , Jongbaeg Kim , Won Gun Koh , Jin Ho Kim
Abstract: Provided is an artificial bladder including: a main body which includes an inlet port, an outlet port, and a predetermined reservoir portion configured to store urine between the inlet port and the outlet port and is formed of a biocompatible polymer that is expandable so that a volume of the reservoir portion changes according to the amount of urine; a sensor which is attached to an outer wall of the main body, has a surface having a wrinkled structure, and is provided so that, when the volume of the reservoir portion increases, the wrinkled structure stretches out and resistance of the sensor changes; and an actuator which is provided at the outlet port and is configured to discharge the urine according a result detected by the sensor.
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公开(公告)号：US20220366812A1
公开(公告)日：2022-11-17
申请号：US17618286
申请日：2020-09-22
Inventor： Jai Ho CHOI , Yong Sam SHIN
IPC: G09B23/30
Abstract: Proposed is a blood vessel model simulation apparatus that is configured to conduct a test or a simulation surgery on a blood vessel model of a cerebral blood vessel, the blood vessel model simulation apparatus including: a blood vessel model mounting unit on which a blood vessel model is mounted to allow a blood-mimicking liquid flow; a blood-mimicking liquid tank unit that is integrally attached to the blood vessel model mounting unit and stores a blood-mimicking liquid which is to be supplied to the blood vessel model mounted on the blood vessel model mounting unit; a pump unit that circulates the blood-mimicking liquid stored in the blood-mimicking liquid tank unit via the blood vessel model; and a pump control unit that controls drive of the pump unit.
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公开(公告)号：US11473059B2
公开(公告)日：2022-10-18
申请号：US15769872
申请日：2016-10-19
Inventor： Seok Goo Cho , Nayoun Kim , Jung-Yeon Lim , Keon-Il Im , Young-Sun Nam
IPC: C12N5/0783 , A61K39/235 , C07K16/28 , A61K39/12 , A61K35/17 , C07K16/24 , A61K39/00
Abstract: The present invention relates to a method for inducing and proliferating target virus antigen-specific dual activated T cells, and can produce target virus antigen-specific dual activated T cells by treating monocytes, which are isolated from peripheral blood, with a cytokine and a virus antigen peptide mixture and culturing the same.
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公开(公告)号：US20220213556A1
公开(公告)日：2022-07-07
申请号：US17609871
申请日：2020-03-26
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
Inventor： Chan Kwon JUNG , Yong Sung KIM , Jong Lyul PARK
IPC: C12Q1/6886 , C12Q1/6858
Abstract: A method for analyzing the methylation level of a specific CpG site in genomic DNA and a composition suitable to use in the method are provided. The method and composition can provide information useful for diagnosing thyroid cancer or determining the prognosis of patients with thyroid cancer. By using the method and the composition, thyroid cancer can be easily and accurately diagnosed from biological samples at a low cost.
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