公开(公告)号：US20220105360A1

公开(公告)日：2022-04-07

申请号：US17450127

申请日：2021-10-06

Applicant: Ewha University - Industry Collaboration Foundation ,  Center for Integrated Smart Sensors Foundation

Inventor： Chang-Hyeon Ji ,  Sang Beom Jun

IPC: A61N5/06

Abstract: An optical probe includes a light source configured to generate an optical signal, a plurality of waveguides configured to guide the optical signal to a target, a plurality of electrodes configured to record an electrical signal generated by the target, and a modulator configured to transmit the optical signal of the light source to at least one target waveguide from among the plurality of waveguides.

公开(公告)号：US20220026443A1

公开(公告)日：2022-01-27

申请号：US17293946

申请日：2019-11-05

Applicant: EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION

Inventor： Goo Taeg Oh ,  Sejin Jeon ,  Tae Kyeong Kim ,  Yangsoo Jang ,  Sung-Jin Hong ,  Hye-Young Yun

IPC: G01N33/68 ,  A61K38/17 ,  A61P9/10

Abstract: The present invention pertains to: a marker composition for diagnosing atherosclerosis severity; a composition for diagnosing atherosclerosis severity; an atherosclerosis severity diagnosis kit including the composition; a method for screening substances for preventing or treating atherosclerosis; and a method for providing information about a diagnosis of atherosclerosis severity, wherein LGI3 expression or activity levels are used. According to the present invention, the severity of atherosclerosis can be diagnosed or predicted, and personalized medicine and predictive medicine can be practiced using such information. Moreover, the present invention can treat atherosclerosis without affecting other metabolic phenotypes by administering an LGI3 antagonist.

公开(公告)号：US20210409695A1

公开(公告)日：2021-12-30

申请号：US17473365

申请日：2021-09-13

Applicant: Hyundai Motor Company ,  Kia Motors Corporation ,  Ewha University - Industry Collaboration Foundation

Inventor： Je Won Kang ,  Sang Hyo Park ,  Seung Wook Park ,  Wha Pyeong Lim

IPC: H04N19/107 ,  H04N19/176 ,  H04N19/184 ,  H04N19/513 ,  H04N19/70

Abstract: Image decoding of decoding a sequence of coded pictures on a block-by-block basis is provided. The image decoding incudes decoding a first high-level syntax element from a bitstream to determine, at a sequence level, whether affine motion prediction is allowed. A second high-level syntax element is extracted for each of at least one coding tool from the bitstream depending on the first high-level syntax element. At a picture level, the method determines whether each of the at least one coding tool is allowed. The coding tool includes sample-by-sample adjustment of affine motion prediction samples.

公开(公告)号：US11190761B2

公开(公告)日：2021-11-30

申请号：US17267182

申请日：2020-06-15

Applicant: Hyundai Motor Company ,  Kia Motors Corporation ,  Ewha University—Industry Collaboration Foundation

Inventor： Je Won Kang ,  Sang Hyo Park ,  Seung Wook Park ,  Wha Pyeong Lim

IPC: H04N19/107 ,  H04N19/184 ,  H04N19/70 ,  H04N19/176 ,  H04N19/513

Abstract: Image decoding of decoding a sequence of coded pictures on a block-by-block basis is provided. The image decoding incudes decoding a first high-level syntax element from a bitstream to determine, at a sequence level, whether affine motion prediction is allowed. A second high-level syntax element is extracted for each of at least one coding tool from the bitstream depending on the first high-level syntax element. At a picture level, the method determines whether each of the at least one coding tool is allowed. The coding tool includes sample-by-sample adjustment of affine motion prediction samples.

公开(公告)号：US20210306658A1

公开(公告)日：2021-09-30

申请号：US17263597

申请日：2020-07-08

Applicant: Hyundai Motor Company ,  Kia Motors Coporation ,  Ewha University-Industry Collaboration Foundation

Inventor： Je Won Kang ,  Seung Wook Park ,  Wha Pyeong Lim

IPC: H04N19/52 ,  H04N19/176 ,  H04N19/132 ,  H04N19/70

Abstract: A video decoding apparatus is provided for decoding pictures using inter-prediction. The video decoding apparatus includes a predictor that generates affine prediction samples for respective subblocks in a target block in a current picture to be decoded by performing affine motion prediction on a subblock-by-subblock basis using control point motion vectors which respectively correspond to corners of the target block. The predictor also modifies sample values of the affine prediction samples by executing a first coding tool, the first coding tool compensating for motion according to sample positions in each of the subblocks using the control point motion vectors.

公开(公告)号：US20210095247A1

公开(公告)日：2021-04-01

申请号：US17041050

申请日：2019-03-26

Applicant: EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION

Inventor： Saeyoung PARK ,  Sung Chul JUNG ,  Seo-ha MYUNG ,  Soo Yeon JUNG ,  Jiyeon KIM ,  Namhee JUNG ,  Yeonzi CHOI

IPC: C12N5/0793 ,  A61K35/30

Abstract: The present disclosure relates to a method for differentiating motor neurons from tonsil-derived mesenchymal stem cells, and a cell therapy agent using the same. The differentiation method of the present disclosure exhibits high differentiation potency into motor neurons, and thus enables a large quantity of motor neurons to be secured. Since the cells which are differentiated according to the present disclosure are obtained using discarded tonsillar tissues, there are fewer ethical issues. In addition, the cells are highly applicable as a cell therapy agent because they can be obtained easily in large quantities.

公开(公告)号：US10904567B2

公开(公告)日：2021-01-26

申请号：US16475002

申请日：2016-12-28

Applicant: LG Electronics Inc. ,  EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION

Inventor： Je-Won Kang ,  Soo Kyung Ryu ,  Jaehyun Lim ,  Sunmi Yoo ,  Jaeho Lee ,  Min-Joo Kang

IPC: H04N19/593 ,  H04N19/132 ,  H04N19/174 ,  H04N19/18 ,  H04N19/182

Abstract: Disclosed is a method for encoding/decoding a still image or moving image based on an intra-prediction mode and an apparatus supporting the same. Particularly, a method for processing an image based on an intra prediction mode may include determining an intra prediction mode set used for an intra prediction in a current prediction processing unit among multiple intra prediction mode sets having different resolutions with each other, wherein the resolution represents a degree of distribution of the intra prediction mode in the intra prediction mode set; deriving an intra prediction mode applied to the current prediction processing unit in the determined intra prediction mode set using index information received from an encoder; and generating a prediction sample of the current prediction processing unit based on the derived intra prediction mode, and each of the intra prediction mode sets includes one or more intra prediction modes.

公开(公告)号：US20200300747A1

公开(公告)日：2020-09-24

申请号：US16655391

申请日：2019-10-17

Applicant: Ewha University - Industry Collaboration Foundation

Inventor： Minsuk KIM ,  Hyue Yun KIM

IPC: G01N15/14 ,  G01N21/88 ,  G06T7/20 ,  G16H30/00

Abstract: The present invention relates to a method for cancer cell separation, and more specifically, relates to a method for cancer cell separation using micro-vibration.

公开(公告)号：US20200255513A1

公开(公告)日：2020-08-13

申请号：US16862981

申请日：2020-04-30

Applicant: EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION

Inventor： Kyunglim Lee

IPC: C07K16/24 ,  A61K38/16 ,  A61K39/395 ,  C07K14/47 ,  A61K38/19 ,  A61P27/14 ,  C07K14/52 ,  A61K9/14 ,  A61K9/20 ,  A61K9/48

Abstract: The present invention relates to a receptor-binding domain of an IgE-dependent histamine releasing factor (HRF), and a use thereof, and more specifically, ascertains, as an HRF structural region, and a FL domain and an H2 domain which bind to a receptor of HRF existing in a cell membrane, ascertains the C-terminus domain of the HRF, and ascertains that a material binding thereto inhibits IL-8 secretion, thereby determining that the FL and H2 domains and the C-terminus domain can be utilized in: the development of a therapeutic agent for treatment and prevention of HRF-related disease including allergic diseases such as asthma, rhinitis, atopic dermatitis, and anaphylaxis; inflammatory diseases such as rheumatoid arthritis; and malaria, and a method for screening for the HRF-related diseases.

公开(公告)号：US10731208B2

公开(公告)日：2020-08-04

申请号：US15522812

申请日：2015-10-30

Applicant: EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyukjin Lee ,  Haeshin Lee ,  Ho Yeon Lee ,  Il Young Jung

IPC: C12Q1/6853 ,  B01L7/00 ,  C12M1/38 ,  C12Q1/68 ,  B01L3/00

Abstract: The present invention provides facile and accurate molecular diagnosis of disease-specific genes capable of the naked eye detection through amplifying the target genes to selectively block the fluid path in a microfluidic device. Specifically, the present invention includes an isothermal amplification of target genes through a rolling circle amplification, a microfluidic device for detecting pathogen genes, and a detection method using the same. Therefore, the present invention can conveniently detect a single target gene, such as a single pathogen, or at the same time, several target genes, such as several pathogens, without complicated mechanical equipment.