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231.发明申请公开(公告)号：US20250109383A1
公开(公告)日：2025-04-03
申请号：US18834936
申请日：2023-01-04
Applicant: POSTECH Research and Business Development Foundation , PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
Inventor： Dong-Woo CHO , Byoung Soo KIM , Won-Woo CHO , Min Jun AHN
Abstract: The present invention relates to a method for producing an adipose model through environmental control and an adipose model created using same, the method comprising the steps of: providing a first bioink, which is cell-unfriendly; creating a bath suspension with a predetermined volume by using the first bioink; providing a second bioink comprising preadipocytes; 3Dprinting the second bioink in the bath suspension so as to produce an adipose model; and culturing the bath suspension in which the adipose model is disposed. The method for producing an adipose model through environmental control and the adipose model created using same, according to the present disclosure, form environments for a 3D-printed adipose model, and limit the proliferation area of adipose cells and induce the differentiation thereof, and thus can maximize similarity with actual adipose tissues.
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公开(公告)号：US20250092121A1
公开(公告)日：2025-03-20
申请号：US18576832
申请日：2022-03-28
Inventor： Cheol Sang HWANG , Da Som KIM , Jeong Mok KIM , Ok Hee SEOK
Abstract: The present invention relates to a novel antigen peptide and, more specifically, the antigen peptide is for preparing an antibody capable of specifically detecting formyl-methionine. It has been identified that an antibody prepared using an antigen peptide for the preparation of a formyl-methionine-specific antibody, according to the present invention, has excellent antigen-binding ability at peptide and protein levels and has excellent antigen-binding ability even under a condition in which intracellular formylated protein expression changes. Therefore, an antigen peptide of the present invention can be effectively used in the preparation of antibodies universally recognizing peptides and proteins having formyl-methionine.
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公开(公告)号：US20250077855A1
公开(公告)日：2025-03-06
申请号：US18817862
申请日：2024-08-28
Inventor： Seyoung KIM , Seungkun KIM , Jeonghoon SON
Abstract: The present disclosure relates to a double gate neuromorphic memory device and a manufacturing method thereof. The double gate neuromorphic memory device is an electrochemical device, and includes a bottom gate provided on an upper portion of a semiconductor substrate, a channel area surrounding the upper portion and side surfaces of the bottom gate, a source electrode and a drain electrode provided in contact with both sides of the channel area, and a top gate provided on an upper portion of a channel area between the source electrode and the drain electrode.
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公开(公告)号：US20250074944A1
公开(公告)日：2025-03-06
申请号：US18796506
申请日：2024-08-07
Inventor： Joongoo LEE , Kanghun LEE
Abstract: Non-canonical substrates-acylated tRNA, introduction of non-canonical substrates into a peptide using ribosome catalysis, and method of preparing pharmacologically active motifs are disclosed. The present invention relates to acylated tRNA and introduction of pharmacologically active motif in peptide using ribosome-mediated catalysis and method that enables the production of a peptide having a cyclic motif without a complicated chemical process on an in vitro protein translation system.
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公开(公告)号：US20250064427A1
公开(公告)日：2025-02-27
申请号：US18723846
申请日：2022-12-02
Inventor： Hyung Ham KIM , Yeonggeun KIM
Abstract: The present invention relates to a position tracking-type ultrasonic blood flow monitoring apparatus that can continuously track the position of a blood vessel by adjusting the rotation angle of an ultrasonic probe module according to the position change of the blood vessel. The present invention may provide a blood flow monitoring apparatus comprising a housing having an opening formed at a bottom surface thereof; a first rotation member rotating around a first axis in the housing; a second rotation member mounted to the first rotation member and rotating around a second shaft; and a probe module mounted to the second rotation member, wherein the probe module rotates together with the first rotation member and the second rotation member according to the rotation of the first rotation member and the second rotation member, and can transmit and receive an ultrasonic signal.
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Patent Agency Ranking
236.发明申请公开(公告)号：US20250058017A1
公开(公告)日：2025-02-20
申请号：US18721363
申请日：2022-03-14
Inventor： Jin Ah JANG , Hyeon Ji KIM , Seung Hyeon HWANG
Abstract: One embodiment of the present disclosure provides an extracellular matrix-based hybrid ink for 3D printing, the hybrid ink including an extracellular matrix having an amine group and a modified hyaluronic acid introduced with an ethylenically unsaturated bond functional group, in which the extracellular matrix and the modified hyaluronic acid are in a crosslinked state by a chemical bond formed between at least some of amine groups present in the extracellular matrix and the ethylenically unsaturated bond functional group present in the modified hyaluronic acid. According to an embodiment of the present disclosure, the hybrid ink has mechanical properties suitable for 3D printing through chemical crosslinking between the extracellular matrix and modified hyaluronic acid as constituents, and can control the drug release rate by adjusting the chemical crosslinking density.
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公开(公告)号：US12216776B2
公开(公告)日：2025-02-04
申请号：US18700030
申请日：2022-11-10
Applicant: UNIVERSITY OF MARYLAND, COLLEGE PARK , POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
Inventor： Giuliano Scarcelli , Yoon-Ho Kim , Jin-Hun Kim
Abstract: A system for noise-resistant quantum communication using hyperentanglement includes a quantum system that includes a plurality of qubits, a processor, and a memory. The memory includes instructions stored thereon, which, when executed by the processor, cause the quantum system to access a signal of a quantum system that includes a plurality of qubits and obtain hyperentanglement of the plurality of qubits via an entanglement source. The hyperentanglement of the plurality of qubits is in at least two dimensions, including a first dimension and a second dimension. The instructions, when executed, further cause the quantum system to transmit the hyperentangled plurality of qubits via a communication channel; perform a communication of the signal with the first dimension of the at least two dimensions; and filter results of the communicated signal based on the second dimension of the at least two dimensions.
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公开(公告)号：US20250028038A1
公开(公告)日：2025-01-23
申请号：US18583057
申请日：2024-02-21
Inventor： Kyungtae KIM , Dongkook KANG
Abstract: A target detection method according to the present disclosure includes generating a range-velocity map from a radar signal of an MPSK-MIMO FMCW radar, detecting a plurality of target signals including a real target signal and a ghost target signal for a target with respect to a velocity axis, estimating an angle of arrival of the target by applying a Capon beamforming algorithm to a target detection result, configuring a phase sequence by extracting phase values for the plurality of target signals from the range-velocity map and arranging the phase values in descending order of velocity value, and arranging differently a plurality of prediction phase values derived using the angle of arrival according to a preset rule to obtain a plurality of candidate phase sequences, and calculating a correlation coefficient between the phase sequence and the plurality of candidate phase sequences and identifying a real target signal in the range-velocity map.
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公开(公告)号：US20250025521A1
公开(公告)日：2025-01-23
申请号：US18577252
申请日：2022-07-07
Inventor： Sin-Hyeog IM , Garima SHARMA , Amit Kumar SHARMA , Sunhee PARK
IPC: A61K35/747 , A61K31/715 , A61K35/00 , A61K39/395 , A61K45/06 , A61P35/00
Abstract: The present invention relates to a combination use of a novel Lactobacillus plantarum IMB19 strain and/or polysaccharides derived from the strain with an anticancer drug for preventing or treating tumors. The novel Lactobacillus plantarum IMB19 strain and polysaccharides derived from the strain of the present invention exhibit an excellent ability to stimulate CD8+T cell activity and exhibit excellent Treg cell inhibitory activity, and stimulate and improve antitumor immune response through various mechanisms such as increased macrophage infiltration in CPS tumors and differentiation and reprogramming of macrophages into an inflammatory phenotype (M1). Furthermore, the strain and the polysaccharides may significantly increase antitumor immune response when administered in combination with an anticancer drug, particularly an immuno-anticancer drug such as a PD-1 or PD-L1 inhibitor (e.g., a PD-1 antibody, a PD-L1 antibody, or the like), and exhibit a remarkable tumor growth suppression effect compared to the case of using the anticancer drug alone. Therefore, the present invention can be effectively used to prevent, relieve, or treat tumors through administration in combination with various anticancer drugs.
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公开(公告)号：US12201559B2
公开(公告)日：2025-01-21
申请号：US17477658
申请日：2021-09-17
Applicant: POSTECH Research and Business Development Foundation , Kyungpook National University Industry-Academic Cooperation Foundation
Inventor： Wan Kyun Chung , Ikjong Park , Hong Kyun Kim , Hyung Gon Shin
IPC: A61F9/007
Abstract: A vacuum tweezer according to the present disclosure includes: a first plate and a second plate of which first and second needle holes facing each other are drilled at lower ends of each, and are positioned to face each other; and a first side plate and a second side plate connecting and fixing the first plate and second plate to form a tube and including a recess portion that is concave downward at a higher position than the first and second needle holes, respectively.
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