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公开(公告)号：US11826324B2
公开(公告)日：2023-11-28
申请号：US17126478
申请日：2020-12-18
Applicant: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY , IMMUNOMET THERAPEUTICS INC.
Inventor： Jungsik Song , Beom Seok Kim , Sang Jun Ha , Ji Min Son
IPC: A61K31/155 , A61K31/436 , A61K31/40
CPC classification number: A61K31/155 , A61K31/40 , A61K31/436
Abstract: Provided are a pharmaceutical composition for preventing or treating inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof, the pharmaceutical composition including a compound represented by Formula 1, or a stereoisomer, derivative, solvate, or pharmaceutically acceptable salt thereof, and a method using the pharmaceutical composition. The pharmaceutical composition and the method can be used to effectively prevent or treat inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof.
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公开(公告)号：US20230379134A1
公开(公告)日：2023-11-23
申请号：US17968368
申请日：2022-10-18
Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY
Inventor： Joon-Woo LEE , Jong-Seon NO , Yong-Woo LEE , Seung-Jae CHAE , Young-Sik KIM
CPC classification number: H04L9/008 , H04L9/0631
Abstract: A method of performing a homomorphic permutation by a server includes: generating, via a ciphertext generation portion, a first ciphertext by adding noise to the basic ciphertext; transmitting, via a transmission portion, the first ciphertext to a client; performing, via an operation portion, a predetermined operation on the noise; receiving, via a reception portion, a second ciphertext from the client; and extracting, via an extraction portion, the basic ciphertext on which the predetermined operation is performed, by removing, from the second ciphertext, the noise on which the predetermined operation is performed, wherein the second ciphertext is a ciphertext that is re-encrypted by the client after decrypting the first ciphertext and performing the predetermined operation on the decrypted first ciphertext.
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253.发明授权公开(公告)号：US11824081B2
公开(公告)日：2023-11-21
申请号：US17209762
申请日：2021-03-23
Inventor： Changsoo Lee , Sangwoon Lee , Chan Kwak , Hyungjun Kim , Euncheol Do
IPC: H01L49/02 , H01L27/108 , C04B35/057 , C04B35/01 , C04B35/64 , C04B35/495 , H10B12/00
CPC classification number: H01L28/55 , C04B35/01 , C04B35/057 , C04B35/495 , C04B35/64 , H10B12/038 , H10B12/37
Abstract: Provided are a dielectric thin film, an integrated device including the same, and a method of manufacturing the dielectric thin film. The dielectric thin film includes an oxide having a perovskite-type crystal structure represented by Formula 1 below and wherein the dielectric thin film comprises 0.3 at % or less of halogen ions or sulfur ions.
A2-xB3-yO10-z
In Formula 1, A, B, x, y, and z are disclosed in the specification.-
公开(公告)号：US20230370569A1
公开(公告)日：2023-11-16
申请号：US18139683
申请日：2023-04-26
Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION , AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor： Joongheon KIM , Soyi JUNG , Jae-Hyun KIM , Won Joon YUN , SooHyun PARK
IPC: H04N7/18 , H04N23/661 , B64U10/00
CPC classification number: H04N7/181 , H04N23/662 , B64U10/00 , B64U2101/20
Abstract: Provided is a surveillance system employing a plurality of unmanned aerial vehicles (UAVs), the surveillance system showing improved surveillance performance while optimizing common energy consumption for computing of all the UAVs and also providing a stable visual monitoring service using autonomous mobility of the plurality of UAVs regardless of movement of an object to be monitored and action uncertainty of an adjacent UAV.
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255.发明公开公开(公告)号：US20230357415A1
公开(公告)日：2023-11-09
申请号：US18024143
申请日：2021-09-10
Inventor： Yong Sung KIM , Hae-Sim PARK , Jung Eun KIM , Keunok JUNG , Dong-Hyun LEE
IPC: C07K16/28
CPC classification number: C07K16/2866 , C07K2317/31 , C07K2317/30 , C07K2317/622 , C07K2317/92 , C07K2317/24 , C07K2317/732 , C07K2317/35 , C07K2317/522 , C07K2317/526
Abstract: An IL-4Rα×IL-5Rα bispecific antibody that simultaneously binds to interleukin (IL)-4 receptor a (IL-4Rα, CD124) and IL-5 receptor a (IL-5Rα, CD125) is provided. A multispecific antibody including the bispecific antibody, a nucleic acid encoding the bispecific antibody or multispecific antibody, a vector including the nucleic acid, and cells transformed by the vector are disclosed. Additionally, a method for producing the bispecific antibody and therapeutic uses of the multispecific antibody in preventing or treating allergic diseases, inflammatory diseases, and eosinophilic diseases associated with IL-4, IL-13 and/or IL-5 are disclosed.
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Patent Agency Ranking
256.发明公开公开(公告)号：US20230355710A1
公开(公告)日：2023-11-09
申请号：US17777464
申请日：2020-11-19
Inventor： Seon Yong JEONG , Eunkuk PARK
IPC: A61K38/17 , A61P25/28 , C12Q1/6883 , G01N33/68
CPC classification number: A61K38/1709 , A61P25/28 , C12Q1/6883 , G01N33/6896 , C12Q2600/158 , G01N2800/2814
Abstract: The present invention relates to a composition for diagnosing, preventing, or treating cognitive dysfunction comprising, as an active ingredient, COTL1 protein or a gene encoding same. The COTL1 protein or the gene encoding same of the present invention plays a vital role in mitochondrial morphology regulation. In addition, when the expression thereof is inhibited, learning ability and memory are deteriorated, and when the inhibited expression thereof is recovered, cognitive ability is improved, and thus the COTL1 protein or the gene encoding same can be effectively used in the diagnosis and treatment of cognitive dysfunction.
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公开(公告)号：US11806364B2
公开(公告)日：2023-11-07
申请号：US16652349
申请日：2018-09-28
Applicant: Industry-Academic Cooperation Foundation, Yonsei University , Research & Business Foundation Sungkyunkwan University
Inventor： Sung Jae Shin , Woo Sik Kim , Hong Min Kim , Kee Woong Kwon , Joo Heon Yoon , Won Jung Koh
CPC classification number: A61K35/15 , C12N5/0669 , C12N2501/22 , C12N2501/2306 , C12N2501/24
Abstract: The present invention relates to a method for inducing differentiation of bone marrow cells into myeloid-derived suppressor cells (MDSCs) by treating the bone marrow cells with a toll-like receptor agonist (TLR agonist) or type I interferon, or for inducing dendritic cells from the MDSCs.
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258.发明公开公开(公告)号：US20230353387A1
公开(公告)日：2023-11-02
申请号：US18308341
申请日：2023-04-27
Inventor： Chang Seop PARK , Samuel WOO
CPC classification number: H04L9/3247 , H04L9/0643 , H04L9/30
Abstract: The present disclosure relates to a method and apparatus for electronic signature and, more particularly, to a method and apparatus for performing safe, post-quantum electronic signature using infinite continuity of a hash function and one-time key pairs. A method for electronic signature using a computing device according to one embodiment of the present disclosure comprises obtaining a message to be electronically signed; obtaining a plurality of public keys generated by a key generation algorithm, and based on the plurality of public keys, generating a signature verification value for the message, wherein the signature verification value includes at least one verification factor generated based on the different public keys or a value obtained by merging the different public keys.
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259.发明公开公开(公告)号：US20230352120A1
公开(公告)日：2023-11-02
申请号：US18309208
申请日：2023-04-28
Inventor： Hyongbum Henry KIM , Nahye KIM
Abstract: According to a system for predicting the efficiency and an outcome of a base editor by using deep learning, it is possible to select a base editor from among 63 base editors with various protospacer adjacent motif (PAM) compatibilities and sgRNA for efficient base editing, without extensive experiments. Therefore, the system may be usefully used in all fields where gene editing is applied, such as disease treatment by gene editing.
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公开(公告)号：US20230349927A1
公开(公告)日：2023-11-02
申请号：US18307891
申请日：2023-04-27
Inventor： Seong Chan JUN , Chae Kwang IM , Ji Sang HA , Se Won PARK , Jae Kyeong LEE , Tae Wook LEE
IPC: G01N33/68 , G01N33/543
CPC classification number: G01N33/6896 , G01N33/5438 , G01N2800/2821 , G01N2333/4709
Abstract: Disclosed herein are an RF biosensing system, a method of manufacturing an RF biosensor used in the same, and a method of controlling the same. The RF biosensing system allows dementia screening without any painful or uncomfortable procedure through rapid detection of biomarkers for Alzheimer's disease present in a patient's bodily fluids. In addition, the RF biosensing system is very helpful for preventing Alzheimer's disease due to the ability to detect triggers for dementia long before onset of symptoms and easily monitor the progression of Alzheimer's disease using simple and inexpensive equipment.
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