Nanocomposites and Process for their Production
    23.
    发明申请
    Nanocomposites and Process for their Production 审中-公开
    纳米复合材料及其生产工艺

    公开(公告)号:US20080139729A1

    公开(公告)日:2008-06-12

    申请号:US11632004

    申请日:2004-07-14

    CPC classification number: C01B33/44

    Abstract: The present invention relates to a process of forming a nanocomposite. The process comprises the steps of treating pristine clay with water in order to swell the clay, exchanging the water with an organic solvent while still maintaining the clay in a swollen state, treating the swollen clay with a modifier and then mixing the treated clay with a substance selected from the group consisting of monomers, oligomers and polymers and combinations thereof. Where necessary, the substance is polymerised and the solvent is being removed either prior to, during or after the polymerization.

    Abstract translation: 本发明涉及形成纳米复合材料的方法。 该方法包括以下步骤:用水处理原始粘土以膨胀粘土,用有机溶剂交换水,同时仍然保持粘土处于膨胀状态,用改性剂处理溶胀的粘土,然后将处理过的粘土与 选自单体,低聚物和聚合物的组合物及其组合。 必要时,物质被聚合,溶剂在聚合之前,期间或之后被除去。

    Polymers for the delivery of bioactive agents and methods of their preparation
    24.
    发明授权
    Polymers for the delivery of bioactive agents and methods of their preparation 有权
    用于递送生物活性剂的聚合物及其制备方法

    公开(公告)号:US07309757B2

    公开(公告)日:2007-12-18

    申请号:US10601262

    申请日:2003-06-20

    Abstract: Provided is a poly(amino ester) having a polymer backbone comprising at least one secondary amine linkage and at least one tertiary amine linkage in the polymer backbone. Poly(amino ester)s are prepared via the Michael addition of a bis(acrylate ester)monomer to a diamine monomer, wherein the diamine monomer has one primary amino group and one secondary amino group, and can be end-capped by reaction with a suitable reagent. The inventive poly(amino ester)s may be used as vectors for delivery of a bioactive agent, such as DNA, to a cell.

    Abstract translation: 提供了具有聚合物主链的聚(氨基酯),其在聚合物主链中包含至少一个仲胺键和至少一个叔胺键。 聚(氨基酯)是通过双(丙烯酸酯)单体向二胺单体的迈克尔加成制备的,其中二胺单体具有一个伯氨基和一个仲氨基,并且可以通过与 合适的试剂。 本发明的聚(氨基酯)可以用作向细胞递送生物活性剂如DNA的载体。

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