公开(公告)号：US08257777B2

公开(公告)日：2012-09-04

申请号：US12100602

申请日：2008-04-10

Applicant: Peter Edelman

Inventor： Peter Edelman

IPC: B05D3/06 ,  B05D5/00 ,  A61F2/06

CPC classification number: B05D1/32 ,  A61F2250/0067 ,  A61F2310/0097 ,  B05D3/06 ,  B05D3/065 ,  Y10T428/31

Abstract: Methods and devices for coating a medical device, such as a stent, including the steps of coating the medical device with a photoresist polymeric coating, irradiating a portion of the medical device, optionally applying a post-exposure bake step, and removing all or a portion of the coating from the irradiated portion of the medical device, if a positive photoresist coating material is used, or from a portion of the medical device not exposed to the radiation, if a negative photoresist coating material is used. The photoresist polymeric coating may optionally include a drug.

Abstract translation: 用于涂覆诸如支架的医疗装置的方法和装置，包括以下步骤：用光致抗蚀剂聚合物涂层涂覆医疗装置，照射医疗装置的一部分，可选地应用曝光后烘烤步骤，以及去除所有或一个 如果使用正性光致抗蚀剂涂层材料，或者如果使用负性光致抗蚀剂涂层材料，则来自医疗装置的照射部分的涂层的部分或未暴露于辐射的部分医疗装置。 光致抗蚀剂聚合物涂层可以任选地包括药物。

公开(公告)号：US20080254297A1

公开(公告)日：2008-10-16

申请号：US12100602

申请日：2008-04-10

Applicant: Peter Edelman

Inventor： Peter Edelman

IPC: B32B33/00 ,  B05D7/00

CPC classification number: B05D1/32 ,  A61F2250/0067 ,  A61F2310/0097 ,  B05D3/06 ,  B05D3/065 ,  Y10T428/31

Abstract: Methods and devices for coating a medical device, such as a stent, including the steps of coating the medical device with a photoresist polymeric coating, irradiating a portion of the medical device, optionally applying a post-exposure bake step, and removing all or a portion of the coating from the irradiated portion of the medical device, if a positive photoresist coating material is used, or from a portion of the medical device not exposed to the radiation, if a negative photoresist coating material is used. The photoresist polymeric coating may optionally include a drug.

Abstract translation: 用于涂覆诸如支架的医疗装置的方法和装置，包括以下步骤：用光致抗蚀剂聚合物涂层涂覆医疗装置，照射医疗装置的一部分，可选地应用曝光后烘烤步骤，以及去除所有或一个 如果使用正性光致抗蚀剂涂层材料，或者如果使用负性光致抗蚀剂涂层材料，则来自医疗装置的照射部分的涂层的部分或未暴露于辐射的部分医疗装置。 光致抗蚀剂聚合物涂层可以任选地包括药物。

公开(公告)号：US5707502A

公开(公告)日：1998-01-13

申请号：US680050

申请日：1996-07-12

Applicant: Robert McCaffrey ,  Katarina Tkacik ,  Brian Holman ,  James Flaherty ,  Josef Brown ,  Peter Edelman

Inventor： Robert McCaffrey ,  Katarina Tkacik ,  Brian Holman ,  James Flaherty ,  Josef Brown ,  Peter Edelman

IPC: C12Q1/00 ,  G01N27/26

CPC classification number: C12Q1/001 ,  C12Q1/002 ,  Y10S435/817

Abstract: A sensor for measuring a concentration of an analyte in a solution. The sensor comprises a substrate layer, an electrode layer and an immobilized enzyme layer. The sensor further includes an enzyme/polymer layer and/or a hydrophobic layer. The enzyme/polymer layer includes an enzyme disposed within a polymer matrix. The hydrophobic layer is formed from a material that is more hydrophobic than the immobilized enzyme layer material. In certain embodiments, the sensor includes the enzyme/polymer layer and the hydrophobic layer disposed between the enzyme/polymer layer and the immobilized enzyme layer such that the enzyme/polymer layer is disposed along the hydrophobic layer within an area above the immobilized enzyme layer.

Abstract translation: 用于测量溶液中分析物浓度的传感器。 传感器包括基底层，电极层和固定化酶层。 传感器还包括酶/聚合物层和/或疏水层。 酶/聚合物层包括设置在聚合物基质内的酶。 疏水层由比固定化酶层材料更疏水的材料形成。 在某些实施方案中，传感器包括酶/聚合物层和设置在酶/聚合物层和固定化酶层之间的疏水层，使得酶/聚合物层沿着疏水层设置在固定化酶层上方的区域内。